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Rabies Clinical and Laboratory Diagnosis Advisory

Division of Public Health Surveillance and Response National Institute for Communicable Diseases (NICD) (2022) CC
Rabies is a fatal viral disease, but is preventable in humans. The rabies virus is transmitted to humans through virus-laden saliva from a rabid animal, mostly dogs. The virus is shed in the saliva of an infected animal and can be introduced into another body through bites, scratches and any other ... more
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Desk-guide for diagnosis and management of TB in children - Africa Edition

Graham, S.M.et al. International Union Against Tuberculosis and Lung Disease (2016) C1
3rd edition
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Comprehensive COVID-19 Slideset: Diagnosis and Transmission

Kim, A.; S.R. Lewin and R. Sherer Clinical Care Options (2021) CC
29 Dec 2021. Comprehensive slideset updated regularly to include the latest data and guidance on best practices for COVID-19 diagnosis and prevention of COVID-19 transmission.
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Guidelines for the Diagnosis and Treatment of Malaria in Somalia

Federal Government of Somalia, Puntland & Somaliland, Zonal NMCPsMoH (2016) C1
The main objective of the malaria prevention and control programme in Somalia is to prevent mortality and reduce morbidity due to malaria. The groups most vulnerable to the disease, children aged under 5 years and pregnant women, are especially targeted. Effective case management - early diagnosis a... more
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Neonatal outcomes of pre-diagnosed COVID-19 positive mothers in Nigeria

B. Ezenwa; Fajolu, I.; Makwe, C.; et al. (2021) CC
COVID-19 infection affects all age groups including newborns, however, literature is scarce on the fetal and neonatal outcomes of babies exposed in-utero, especially in Africa. The objectiveof this study was to document the perinatal outcomes of COVID-19 pregnancies and del... more
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Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV
recommended

World Health Organization (WHO) (2022) C_WHO
Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa. These guidelines update the recommendations that were first released i... more
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Global distribution of cases diagnosed and published with Trypanosoma cruzi and HIV coinfection, 2006-2010

World Health Organization WHO (2013) C_WHO
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its fro... more
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Guidelines for the Clinical Diagnosis and Treatment of Dengue, Chikungunya, and Zika

Pan American Health Organisation PAHO (2022) C_WHO
Evidence-based guidelines are one of the most useful tools for improving public health and clinical practice. Their purpose is to formulate interventions based on strong evidence of efficacy, avoid unnecessary risks, use resources efficiently, reduce clinical variability and, in essence, improve hea... more
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Human African trypanosomiasis cases diagnosed in non-endemic countries (2011– 2020)

Franco. J.R.; G. Cecchi, G. Priotto, et al. (2022) CC
PLoS Negl Trop Dis 16(11): e0010885. https://doi.org/10.1371/journal.pntd.0010885 HAT diagnosis in non-endemic countries is rare and can be challenging, but alertness and surveillance must be maintained to contribute to WHO’s elimination goals. Early detection is particularly important as it co... more
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Diphtheria: NICD Recommendations for Diagnosis, Managementand Public Health Response

The National Institute For Communicable Diseases, South Africa (2018) C1
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India: National Guidelines on diagnosis and treatment of Pediatric Tuberculosis

Government of India, Central Tuberculosis Division (2012) C1
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Clinical and Laboratory Diagnosis of Buruli Ulcer Disease: A Systematic Review

Sakyi; S.A.; Aboagye, S. Y.; Otchere, I. D. ; et al The Canadian Journal of Infectious Diseases & Medical Microbiology (2016) C1
Volume 2016 | Article ID 5310718 | https://doi.org/10.1155/2016/5310718. Buruli ulcer (BU) is a necrotizing cutaneous infection caused by Mycobacterium ulcerans. Early diagnosis is crucial to prevent morbid effects and misuse of drugs. We review developments in laboratory diagnosis of BU, discuss li... more
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Schistosomiases Clinical guidelines - Diagnosis and treatment manual

Dubois, G.; Vasseur-Binachon, B.; Yoshimoto, C. et al. Médecins Sans Frontières (MSF) (2022) CC
Schistosomiases are acute or chronic visceral parasitic diseases due to 5 species of trematodes (schistosomes). The three main species infecting humans are Schistosoma haematobium, Schistosoma mansoni and Schistosoma japonicum. Schistosoma mekongi and Schistosoma intercalatum have a more limited dis... more
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Clinical Testing and Diagnosis for Schistosomiasis

Centers for disease control and prevention CDC (2025) C_CDC
Website accessed Feb 6, 2025
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Chronic obstructive pulmonary disease in over 16s: diagnosis and management

National Institute for Health and Care Excellence - NICE (2018) CC2
This guideline covers diagnosing and managing chronic obstructive pulmonary disease or COPD (which includes emphysema and chronic bronchitis) in people aged 16 and older. It aims to help people with COPD to receive a diagnosis earlier so that they can benefit from treatments to reduce symptoms, impr... more
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Hepatitis B (chronic): Diagnosis and management of chronic hepatitis B in children, young people and adults

Aftab Ala, Elizabeth Boxall, Steven Bradley et al. National Clinical Guideline Centre (2013)
Clinical guideline, Methods, Evidence and Recommendations In this guideline the following is covered: information needs of people with chronic hep titis B and their carers; where children, young people and adults with chronic hepatitis B a- should be assessed; assessment of liver disease, includi... more
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Severe and Difficult Asthma: Diagnosis and Management—Challenges for a Low‐Resource Environment

Bush, A. Springer Link (2021) CC2
Severe and difficult asthma in a low- and middle-income country (LMIC) can relate to lack of availability of basic medications; potentially reversible factors such as poor adherence or comorbidities such as obesity inhibiting a good response to treatment; and (rarely) true severe, therapy-resistant ... more
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Bench Aids Diagnosis Malaria Infections

World Health Organization (2000) C_WHO
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Guidance on Diagnosis and Management of People with Post-Acute COVID-19 Syndrome
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2021) C_CDC
This guidance covers diagnosis and care of patients with long-term effects of COVID-19. It makes recommendations for the care of adults and children who have new or ongoing symptoms 4 weeks or more after the start of acute COVID-19. It is meant for health and care practitioners. This interim documen... more
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Algorithm for laboratory diagnosis and treatment-monitoring of pulmonary tuberculosis and drug-resistant tuberculosis using state-of-the-art rapid molecular diagnostic technologies

World Health Organization (2017) C_WHO
Expert opinion of the European Tuberculosis Laboratory Initiative core group members for the WHO European Region.