Long-term exposure of humans to air pollution enhances the risk of cardiovascular and respiratory diseases. A novel Global Exposure Mortality Model (GEMM) has been derived from many cohort studies, providing much-improved coverage of the exposure to fine particulate matter (PM2.5). We applied the GE...MM to assess excess mortality attributable to ambient air pollution on a global scale and compare to other risk factors.
Methods and results
We used a data-informed atmospheric model to calculate worldwide exposure to PM2.5 and ozone pollution, which was combined with the GEMM to estimate disease-specific excess mortality and loss of life expectancy (LLE) in 2015. Using this model, we investigated the effects of different pollution sources, distinguishing between natural (wildfires, aeolian dust) and anthropogenic emissions, including fossil fuel use. Global excess mortality from all ambient air pollution is estimated at 8.8 (7.11–10.41) million/year, with an LLE of 2.9 (2.3–3.5) years, being a factor of two higher than earlier estimates, and exceeding that of tobacco smoking. The global mean mortality rate of about 120 per 100 000 people/year is much exceeded in East Asia (196 per 100 000/year) and Europe (133 per 100 000/year). Without fossil fuel emissions, the global mean life expectancy would increase by 1.1 (0.9–1.2) years and 1.7 (1.4–2.0) years by removing all potentially controllable anthropogenic emissions. Because aeolian dust and wildfire emission control is impracticable, significant LLE is unavoidable.
Conclusion
Ambient air pollution is one of the main global health risks, causing significant excess mortality and LLE, especially through cardiovascular diseases. It causes an LLE that rivals that of tobacco smoking. The global mean LLE from air pollution strongly exceeds that by violence (all forms together), i.e. by an order of magnitude (LLE being 2.9 and 0.3 years, respectively).
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Le paludisme reste un enjeu majeur de santé publique dans de nombreux pays à faible et moyen revenu. En 2018, l’OMS estimait à environ 228 millions le nombre de cas de paludisme, responsable de 405 000 décès principalement en Afrique subsaharienne. L’utilisation intensive des outils antipal...udiques disponibles a permis de réduire significativement la transmission dans de nombreuses régions endémiques au cours de la dernière décennie. Cependant, l’éradication du paludisme dans les zones à forte transmission reste une perspective lointaine.
Ce MOOC offre aux participants un aperçu complet des diverses disciplines et questions clés de la recherche sur le paludisme. Il aborde notamment la biologie cellulaire et moléculaire des parasites, la recherche clinique sur le terrain et en milieu hospitalier, les technologies génomiques avancées, la recherche translationnelle sur les nouveaux outils de lutte contre les parasites et vecteurs (médicaments, vaccins), l’épidémiologie du paludisme et la recherche clinique en santé publique. Le cours est accessible à toute personne intéressée par le paludisme, à condition de posséder une formation initiale en sciences de la vie.
Ce MOOC fait partie des MOOCs du Diplôme des Maladies Infectieuses de l’Institut Pasteur (DNM2IP).
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Guidance module.
The QualityRights training and orientation modules have been developed to enhance the knowledge, skills and understanding of key stakeholders on how to promote the rights of people with psychosocial, intellectual or cognitive disabilities, improve the quality of services and suppo...rt provided in the field of mental health and related areas, in line with international human rights standards, in particular the UN Convention on the Rights of Persons with Disabilities and the recovery approach.
mental health and related fields, in accordance with international human rights standards, in particular the UN Convention on the Rights of Persons with Disabilities and the recovery approach.
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utilisant le programme d'action de l'OMS «Combler les lacunes en santé mentale -Guide d'intervention humanitaire (mhGAP-GIH
Accès au site Octobre 2019
Guide de l'Apprenant
DRUGS REGULATORY UNIT | NOVEMBER 2009 | SECOND EDITION
Accessed: 21.03.2019
mhGAP Training Manual for the mhGAP Intervention Guide for mental, neurological and substance use disorders in non-specialized health settings – version 2.0 (for field testing)
LESOTHO COPDAM BASELINE STUDY 2013
Here you will find poster for vaccination sites, patient care areas, at the entrances, hand hygiene, PPE, Cleaning
ERJ Open Res 2017; 3: 00002-2017
Here you will find poster for vaccination sites, patient care areas, at the entrances, hand hygiene, PPE, Cleaning
The new, all oral, 20-month MDR-TB regimens range from US $1,600* (using bedaquiline and linezolid for 6 months and levofloxacin as the fluoroquinolone) to US $2,100* (using linezolid for 12 months and moxifloxacin as the fluoroquinolone.