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Clinical Pharmacology: Advances and Applications, 2025:17 29–47
Preferred product characteristics and clinical development considerations
Malaria vaccines: the 60‑year journey of hope and final success—lessons learned and future prospects
Tropical Medicine and Health (2023) 51:29
The aim of this protocol is to support the conduct of entomological comparative efficacy assessments for vector control products and the associated non-inferiority analysis. This evidence is used to inform discussions within the guidelines development context as to whether a new vector control prod
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uct should be considered as covered by one or more existing WHO recommendations or not. Alternatively, the evidence may inform the extension of an existing WHO recommendation or the development of a new one, provided that non-inferiority is demonstrated
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La lutte antivectorielle est un élément essentiel des stratégies de prévention, de contrôle et d'élimination du paludisme, car elle peut s'avérer très efficace pour assurer la protection des personnes et/ou réduire la transmission de la maladie.
Vector control, alongside case management, remains the most effective approach to controlling and eliminating malaria. Key interventions, such as indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs), have significantly reduced malaria transmission in many African countries. This
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has enabled some countries to transition from the control phase to the elimination phase.
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The purpose of the guideline is to provide information to stakeholders on the necessary requirements for a complete prequalification dossier for insecticide-treated nets (ITNs). Its aim is to establish the baseline for dossier requirements which are necessary to assess ITN products for the purposes
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of prequalification, describe the data requirements for fulfilling each dossier module, and to provide standardized information for applicants and testing facilities generating data for ITN prequalification dossiers. The document is supported by implementation guidance documents which provide specific information and considerations for how applicants may approach the generation of supporting information and compilation of a complete product dossier.
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Malaria Journal (2021) 20:190
Ce chapitre fait partie du Rapport 2024 sur les résultats.
Depuis 2010, la lutte contre le paludisme a permis de réaliser des progrès majeurs grâce à la distribution de moustiquaires, au diagnostic rapide, aux traitements à base d'artémisinine (ACT) et aux interventions préventives ciblées.
Directives nationales pour la prise en charge du paludisme en République Démocratique du Congo
Programme National de Lutte contre le Paludisme (PNLP)
Ministère de la Santé Publique, Hygiène et Prévention, République Démocratique du Congo
(2023)
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Le document « Directives nationales pour la prise en charge du paludisme en RDC », publié en 2023 par le PNLP et le Ministère de la Santé, définit les protocoles officiels pour diagnostiquer et traiter le paludisme sur l’ensemble du territoire. Il recommande l’usage systématique du te
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st de diagnostic rapide avant tout traitement, et l’administration des CTA pour le paludisme simple et de l’artésunate injectable pour les cas graves. Le texte insiste sur la gratuité des soins pour les enfants de moins de 5 ans et les femmes enceintes, la gestion rationnelle des médicaments et la formation continue du personnel de santé. Ces directives visent à réduire la mortalité et à atteindre l’élimination du paludisme d’ici 2030.
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According to the WHO, there were an estimated 251 million malaria cases (95% of global cases) and 579,414 malaria deaths (97% of global deaths) in African Union Member States in 2023. 76% of these deaths were children under the age of five.
SuperBetter Children is a health and wellbeing curriculum designed to be integrated into school programmes or offered as an extracurricular activity.
The '100 Health Messages for Children to Learn & Share' is an educational resource developed by Children for Health. It is aimed at children aged 8–14, particularly young adolescents (aged 10–14), who often care for younger siblings. The set contains 100 simple, accurate and adaptable health mes
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sages, with 10 messages on each of the following topics: Malaria, diarrhoea, nutrition, coughs and colds, intestinal worms, water and sanitation, immunisation, HIV and AIDS, accidents and injuries, and early childhood development. The messages have been reviewed by medical and education experts and are designed for use by parents, teachers and health workers in schools, homes, clinics and clubs. The resource encourages active learning through memorisation, discussion, and creative activities, empowering children to become health educators in their communities.
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Manual para aplicar rociado residual intradomiciliario en zonas urbanas para el control de Aedes aegypti no solo está dirigido al personal operativo y los mandos medios y directivos de los programas de prevención y control de las enfermedades transmitidas por Aedes, sino también a la comunidad ac
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adémica relacionada con la investigación operativa sobre RRI-Aedes, a los controladores de plagas privados y al público en general.
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Ce manuel est destiné aux prestataires de soins chargés de la prise en charge des cas de paludisme simple et grave au niveau des structures de santé. C’est un document de référence facile d’utilisation, fournissant des connaissances et des compétences utiles aux agents de santé prenant e
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n charge les cas de paludisme.
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Evidence-based Malaria BCC Module 4 e-learning series.
Accessed July 2025
This training module on malaria case management has been developed to support the staff involved in malaria control and elimination programmes in the effective organization of malaria diagnosis and case management services
