Arsenical monotherapies were previously very successful for treating human African trypanosomiasis (HAT).
Melarsoprol resistance emerged as early as the 1970s and was widespread by the late 1990s.
Melarsoprol resistance represents the only example of widespread drug resistance in HAT patients wher...e the genetic mechanism has been established.
The current goal of elimination of HAT as a public health problem by 2020 may be undermined by the emergence and spread of resistance to current or new drugs.
Insights into potential resistance mechanisms for current and new drugs will facilitate predictions of the likelihood of resistance and will also facilitate rational approaches to minimizing, monitoring, and tackling the future emergence of resistance.
more
Consultancy to take forward the International Health Partnership
dos Santos et al. BMC Public Health 2014, 14:80 http://www.biomedcentral.com/1471-2458/14/80
A statement by the Catholic Bishops' Conference of England and Wales
1996
Published:February 02, 2021DOI:https://doi.org/10.1016/S0140-6736(21)00234-8
The 6th edition of the essential medicine list has been developed based on the 5th edition list of essential medicines, the National Standard Treatment Guidelines and Protocols 2013, list of laboratory commodities and List of Consumables used in public health facilities.
Irresponsible pharmaceutical companies fuel the proliferation of superbugs through supply chain pollution, the European Public Health Alliance (EPHA) reports. The advocacy group uncovered lapses such as dirty production and inadequate waste disposal in the production of antimicrobials in China and I...ndia, which supplies most of the antimicrobials consumed in Europe. In a briefing detailing the pollution, the EPHA urges major purchasers of antibiotics to blacklist irresponsible pharmaceutical companies, demand that the industry clean up its supply chain, introduce greater transparency on the origin of antibiotics, and review and revise procurement policies from an ethics perspective.
more
What are the local beliefs and practices around illnesses and death, the transmission of disease and spirituality, which affect decision-making (around health-seeking behaviour, caring for relatives and nature of burials) and can inform effective behaviour change interventions for preventing Ebola i...n Sierra Leone?
more
Hindawi Publishing Corporation
Tuberculosis Research and Treatment
Volume 2015, Article ID 752709, 7 pages
Research Paper, Accessed April 10,2019
L’enquête ENPS 2016 avait pour objectif de mesurer la situation des indicateurs d’accessibilité et d’utilisation des moyens préventifs et curatifs définis dans le cadre des directives du PNLP au Sénégal. Elle entre dans le cadre de l’évaluation périodique du niveau de réalisation de...s objectifs et des résultats attendus à partir de données du terrain afin d’adapter continuellement les décisions aux réalités du terrain. En particulier, cette étude s’est intéressée à documenter la situation des indicateurs de couverture et d’utilisation des différentes interventions de lutte contre le paludisme. En particulier, la couverture et l’utilisation ou exposition des moyens préventifs (MI, TPI chez la femme enceinte, AID et CPS dans les zones ciblées) ont été documentés ainsi que les types et modalités de la prise en charge des cas de fièvre chez l’enfant et la femme enceinte. Par ailleurs, ces indicateurs ont été renseignés en tenant compte des variations régionales, de districts et du milieu de résidence (urbain et rural). L’analyse a aussi tenu compte des variations liées aux faciès épidémiologiques et des zones d’intervention couvertes par les différentes stratégies.
more
This publication seeks to describe the best treatments and practices based on the scientific evidence available at the time of writing as evaluated by the authors and may change as a result of new research. Readers need to apply this knowledge to patients in accordance with the guidelines and laws o...f their country of practice. Some medications may not be available in some countries and readers should consult the specific drug information since not all the unwanted effects of medications are mentioned.
more