This position paper on polio vaccines replaces the 2016 WHO position paper, and summarizes recent developments in the field.
Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa.
These guidelines update the recommendations that were first released i...n 2018 on diagnosing, preventing, and managing cryptococcal disease. In response to important new evidence that became available in 2021, these new guidelines strongly recommend a single high dose of liposomal amphotericin B as part of the preferred induction regimen for the treatment of cryptococcal meningitis in people living with HIV. This simplified regimen - a single high dose of liposomal amphotericin B paired with other standard medicines (flucytosine and fluconazole) - is as effective as the previous WHO standard of care, with the benefits of lower toxicity and fewer monitoring demands.
The objective of these guidelines is to provide updated, evidence-informed recommendations for treating adults, adolescents and children living with HIV who have cryptococcal disease. These guidelines are aimed at HIV programme managers, policymakers, national treatment advisory boards, implementing partners and health-care professionals providing care for people living with HIV in resource-limited settings with a high burden of cryptococcal disease.
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Près de deux ans après la signature de l’Accord Politique pour la Paix et la Réconciliation (APPR), la population centrafricaine est toujours l’otage d’un environnement sécuritaire instable et imprévisible. La poursuite des conflits dans plusieurs zones du pays, les faiblesses structurell...es conjuguées aux effets socio-économiques de la pandémie de COVID-19 et aux effets dévastateurs des catastrophes naturelles ont plongé 2,8 millions de personnes dans une grande vulnérabilité. Sur ce total, 1,9 million connaissent des besoins humanitaires sévères, un chiffre inégalé depuis 5 ans qui traduit une détérioration du bien-être physique et mental et des conditions de vie des populations dans l’ensemble du pays.
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First published in 2020, this toolkit is intended for clinicians working in acute care, managing adult and paediatric patients with acute respiratory infection, including severe pneumonia, acute respiratory distress syndrome, sepsis and septic shock. The main objective is to provide key tools for us...e in the care of critically ill patients – from hospital entry to hospital discharge.
The 2022 updated version includes new tools and adapted algorithms, checklists, memory aids for COVID-19 and influenza, and the latest clinical evidence regarding clinical management of SARI. It is intended to help clinicians care for SARI patients: from epidemiology of severe acute respiratory infections, screening and triage, infection prevention and control, monitoring of patients, laboratory diagnosis, principles of oxygen therapy and different types of ventilation (invasive and non-invasive), as well as antimicrobial and immunomodulator therapies, to ethical and quality of care assessments.
The first edition is availbel in Ukrainian and Russian
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This guideline covers identifying, assessing and managing the long-term effects of COVID-19, often described as ‘long COVID’. It makes recommendations about care in all healthcare settings for adults, children and young people who have new or ongoing symptoms 4 weeks or more after the start of a...cute COVID-19. It also includes advice on organising services for long COVID.
Updated 11 November 2021
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N Engl J Med 2022; 386:911-922, DOI: 10.1056/NEJMoa2104535
Four months of antituberculosis treatment was noninferior to 6 months of treatment in children with drug-susceptible, nonsevere, smear-negative tuberculosis (SHINE Study)
The Updated guidelines on Management of tuberculosis in children and adolescents include new recommendations that cover diagnostic approaches for TB, shorter treatment for children with non-severe drug-susceptible TB, a new option for the treatment of TB meningitis, the use of bedaquiline and delama...nid in young children with multidrug- and rifampicin-resistant TB and decentralized and family-centred, integrated models of care for TB case detection and prevention in children and adolescents.
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Wearing a face mask can help reduce the spread of COVID-19 in the community by reducing the release of respiratory droplets from asymptomatic / pre-symptomatic individuals or those with mild non-specific symptoms. The use of face masks for this purpose may be adopted to reduce the societal impact as...sociated with absence from work or healthcare pressures due to infection, or to protect vulnerable individuals in particular settings.
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Biosafety involves the implementation of containment principles, technologies and practices to prevent unintentional exposure to biological agents. Biosecurity involves the protection, control and accountability of biological materials and information related to these materials and dualuse research,... to prevent their unauthorized access, loss, theft, misuse, diversion or intentional release.
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Interim rapid response guidance, 10 June 2022.
It includes considerations for certain populations such as patients with mild disease with considerations for community care, patients with moderate to severe disease, sexually active persons, pregnant or breastfeeding women, children and young persons.... The guidance also addresses considerations for clinical management such as the use of therapeutics, nutritional support, mental health services, and post-infection follow-up.
The document provides guidance for clinicians, health facility managers, health workers and infection prevention and control practitioners including but not limited to those working in primary care clinics, sexual health clinics, emergency departments, infectious diseases clinics, genitourinary clinics, dermatology clinics, maternity services, paediatrics, obstetrics and gynaecology and acute care facilities that provide care for patients with suspected or confirmed monkeypox
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Accessed on 20.08.2022#
Actualización en Profilaxis Post Exposición (PPE) en Niños, Niñas y Adolescentes
WHO recommends prompt recognition of progressive acute hypoxaemic respiratory failure when a patient with respiratory distress is failing to respond to standard oxygen therapy and adequate preparation to provide advanced oxygen/ventilatory support.
Hypoxaemic respiratory failure in ARDS commonly re...sults from intrapulmonary ventilation-perfusion mismatch or shunt and usually requires mechanical ventilation.
At any time, if there are urgent or emergent indications for intubation, do not delay.
WHO suggests that hospitalized patients with severe or critical COVID-19 with acute hypoxaemic respiratory failure that do not require emergent intubation be treated with HFNO, or CPAP or NIV (BiPAP) rather than standard oxygen therapy.
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Le présent guide opérationnel sert de feuille de route pour la surveillance et les interventions en matière de mortalité maternelle et périnatale dans les milieux cliniques et politiques, comme décrit dans les deux guides de référence de l’Organisation mondiale de la santé (OMS) intitulé...s : Surveillance des décès maternels et riposte – Directives techniques – Prévention des décès maternels – Informations au service de l’action («Guide SDMR», 2013) et Pour que chaque enfant compte : audit et examens des mortinaissances et des décès néonatals» (2016).
Ces deux guides proposent des approches fondées sur l’utilisation de données de qualité sur les soins de santé pour mettre un terme aux décès maternels, aux mortinaissances et aux décès néonatals évitables.
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The escalation of the war in Ukraine began on 24 February 2022, causing thousands of civilian
casualties; destroying civilian infrastructure, including hospitals, and triggering the fastest-
growing displacement crisis in Europe since World War II. The demographic profile of Ukraine,
combined wit...h the implementation of martial law and conscription policies, led to an awareness
of gender- and age-related factors within the regional humanitarian response that recognised
the pre-crisis situation of persons of all genders and diversities and how the war and subsequent
regional crisis were compounding the risks that they face.
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Mettre fin au choléra- Feuille de route mondiale pour 2030 rend opérationnelle la nouvelle stratégie mondiale de lutte contre le choléra au niveau des pays et fournit une voie concrète vers un monde où le choléra ne représente plus une menace pour la santé publique. En mettant en œuvre la ...stratégie d’ici à 2030, les partenaires du Groupe spécial mondial de lutte contre le choléra (GTFCC) aideront les pays à réduire de 90 % les décès dus au choléra. Avec l’engagement des pays touchés par le choléra, des partenaires techniques et des donateurs, pas moins de 20 pays pourraient éliminer la transmission de la maladie d’ici 2030.
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Le présent document vise à fournir des indications aux pays pour identifier les zones
d’intervention prioritaires dans le cadre de l’analyse de la situation prévue dans leur plan
national de contrôle et d’élimination du choléra (PNC).