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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc ... e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

Essential WASH Actions: A Training & Reference Pack to Supplement Essential Nutrition Actions

Rosenbaum, Julia and Bery, Renuka (2017) C1

The Essential WASH Actions toolkit expands the connection between WASH and nutrition. This resource offers a comprehensive set of essential WASH actions, references training materials for health workers, nutrition managers and community workers to b ... more

Practical guide to inclusive and rights-based responses to Covid-19 in the Americas

OAS (2020) CC

WHY THIS GUIDE? Because, in the face of crises and emergencies, it is vital to include a human rights perspective in responses. Vulnerable groups face major obstacles to accessing and benefiting from prevention, mitigation, and health care policies ... more

World Heart Federation Roadmap for Hypertension – A 2021 Update

Jemoon, P.; Séverin, T.; Amodeo, C. et al. Global Heart (2021) CC

The World Heart Federation (WHF) Roadmap series covers a large range of cardiovascular conditions. These Roadmaps identify potential roadblocks and their solutions to improve the prevention, detection and management of cardiovascular diseases and provide a generic global framework available for loca ... more

Air pollution exposure—the (in)visible risk factor for respiratory diseases

Bălă, G.P.; Râjnoveanu, R.M.; Tudorache, E. et al. Environmental Science and Pollution Research (2021) CC

There is increasing interest in understanding the role of air pollution as one of the greatest threats to human health worldwide. Nine of 10 individuals breathe air with polluted compounds that have a great impact on lung tissue. The nature of the r ... more

International technical guidance on sexuality education. An evidence-informed approach.

UNESCO (2018) CC

This revised and fully updated edition of the International technical guidance on sexuality education benefits from a new review of the current evidence, and reaffirms the position of sexuality education within a framework of human rights and gender equality. It promotes structured learning about ... more

Patient- and provider-related factors in the success of multidrug-resistant tuberculosis treatment in Colombia

Puerto Castro GM, Montes Zuluaga FN, Alcalde-Rabanal JE, Pérez F, et al. PAHO (2021) C_WHO

Rev Panam Salud Publica. 2021;45:e74. Some characteristics of patients and healthcare providers influence treatment success in MDR-TB cases. Physicians’ and nurses’ knowledge about MDR-TB must be improved, and follow-up of MDR-TB patients who are living with HIV and of those affiliated with the ... more

Defeating Cholera

Centers for Disease Control and Prevention CDC (2010) C_CDC

Clinical Presentation and Management for Haiti Cholera Outbreak, 2010 The document provides detailed guidelines for diagnosing and managing cholera cases, with a focus on rehydration therapy and preventing dehydration-related fatalities. It outlines the use of oral rehydration salts (ORS), intrav ... more

Disease Surveillance, Emergency Preparedness and Response in Eastern and Southern Africa

World Bank, et al. (2021) CC

A Situational Assessment and Five-YearAction Plan for the Africa CDC Strengthening Regional Public Health Institutions and Capacity for Surveillance and Response Program

Reconhecimiento de doenças tropicais negligenciadas pelas alterações cutâneas

Organização Mundial da Saúde (OMS) (2018) C_WHO

Guia de treinamento para profissionais de saúde da linha de frente Versão oficial em português da obra original em Inglês Recognizing neglected tropical diseases through changes on the skin: a training guide for front-line health workers

From Research to Action: Advancing Prevention and Response to Violence against Children: Report on the Global Violence against Children Meeting

UNICF (2014)

Growing evidence indicates that large proportions of children around the world experience physical, sexual and emotional violence every year, with enormous implications for human rights, public health and economic and social development.1 Over the l ... more

Guidelines for Use of the APCA African Palliative Outcome Scale

African Palliative Care Association APCA (2011) C2

The Guidelines for the Use of the APCA African Palliative Outcome Scale (POS) has been developed by the APCA, in collaboration with stakeholders, to help appropriately trained health practitioners and researchers across the region to utilise t ... more

Maternal, Infant and Young Child Nutrition MIYCN Guidelines

Republic of South Sudan (2017) C1

Maternal, Infant and Young Child Nutrition Strategic Actions:
1 Endorse and disseminate key policies and regulations
2 Improve maternal nutrition
3 Protect, promote, and support optimal infant and young child feeding practices
4 Support optimal infant and young child feeding in ... more

Solidarity in response to the COVID-19 pandemic

Rahman-Shepherd, A.; C. Clift; E. Ross; et al. The Chatham House (2021) CC

Has the world worked together to tackle the coronavirus? July 2021. This research paper assesses how the global community has responded to calls for greater solidarity in tackling the COVID-19 pandemic, and presents the insights of key stakeholders and experts in global ... more

Social Appropriation of Knowledge and its contributions to the prevention of cutaneous leishmaniasis in rural contexts

Paipilla, K., Castro-Arroyave, D., Grajales,L. BMJ Innovations :234–239. doi:10.1136bmj (2022) CC

Cutaneous leishmaniasis (CL) is a neglected infectious endemic disease that is transmitted through the bite of a vector insect (sandfly) of the Lutzomyia genus,typical of rural geographical territories, and causes disfiguring skin ulcers and disabilities. It is estimated that CL affects between 600 ... more

The sociodemographic impacts of the COVID-19 pandemic in Latin America and the Caribbean

United Nations ECLAC (2022) C1

Latin America and the Caribbean is characterized by a matrix of social inequality whose axes —such as socioeconomic stratum, gender, stage in the life cycle, ethnicity and race, territory, disability, and immigration status— create multiple, often concurrent, situations of exclusion and discri ... more

AFRICA CDC Framework for Antimicrobial Resistance, 2018-2023

Africa CDC (2018) C_CDC

Antimicrobial resistant (AMR) organisms are increasing globally, threatening to render existing treatments ineffective against many infectious diseases. In Africa, AMR has already been documented to be a problem for HIV and the pathogens that cause malaria, tuberculosis, typhoid, cholera, meningitis ... more

Earthquake Haiti: Guidelines and Resources
recommended

Mauder, S. MEDBOX (2021) CC

25 August 2021. The earthquake on August 14, 2021 was almost as strong as the severe quake in 2010, which killed about 300,000 people. The current number of victims is more than 2,200 people, and more than 12,000 people have been injured. More than 52,000 houses were destroyed and more than 77,000 ... more