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Diphtheria is caused by Corynebacterium species, mostly by toxin-producing Corynebacterium diphtheriae and rarely by toxin-producing strains of C. ulcerans and C. pseudotuberculosis. The most common type of diphtheria is classic respiratory diphtheria, whereby the exotoxin produced characteristicall ... more
Two malaria vaccines are currently WHO prequalified and recommended1 for use to prevent P. falciparum malaria in young children, the RTS,S/AS01 vaccine, currently manufactured by GlaxoSmithKline (GSK), and the R21/Matrix-M ... more
Presentation OPT-SMC malaria vaccine workshop - Jan 2023
2016 revision
Available in English, French, Portuguese and Arabic Successful immunization of a critical mass of the African population with one or several safe and efficacious COVID-19 vaccines.Key objectives1. Accelerate African involvement in the clinical development of a ... more
Interim Guidance October 2022. This addendum addresses some of the methodological aspects of VE evaluations that have been learned during the past year, as well as those that have become relevant in the current epidemiological setting of the COVID-19 pandemic. For some of the COVID-19 ... more
Many critical questions remain about the effectiveness of COVID-19 vaccines in real-world settings. These questions can only be answered in post-introduction vaccine effectiveness studies.This guidance document outlines an approach to leverage exist ... more
Despite high regional demand for vaccines valued at over US$ 1 billion annually, Africa’s vaccine industry provides only 0.1% of global supply. Vaccine inequity and hoarding at the start of the pa ... more
Each year WHO and UNICEF jointly review reports submitted by Member States regarding national immunization coverage, finalized survey reports as well as data from the published and grey literature. Based on these data, with due consideration to pote ... more
2016 revision
Data received as of July 3, 2017 | WHO and UNICEF estimates of national immunization coverage - next revision available July 15, 2018
WHO Secretariat Information paper July 2016
Lancet Glob Health 2016; 4: e856–63. Open Access The article "Effectiveness of one dose of oral cholera vaccine in response to an outbreak: a case-cohort study" investigates whether a single dose of the Shanchol oral cholera ... more
Protection from a Single Dose of HPV Vaccine A major public health impact from IARC studies of vaccine efficacy.
Updated 28 December 2020