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Publication Years
1345
3715
563
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3
Category
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2
Toolboxes
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GETTING TO KNOW CEREBRAL PALSY: Module 1 - Introduction
Hambisela - Towards Excellence in Therapy for Cerebral Palsy
Cerebral Palsy Association (Eastern Cape)
(2008)
C2
A learning resource for facilitators, parents, caregivers, and persons with cerebral palsy | Version 1 - Released March 2008
GETTING TO KNOW CEREBRAL PALSY: Module 2 - Evaluating Your Child
Hambisela - Towards Excellence in Therapy for Cerebral Palsy
Cerebral Palsy Association (Eastern Cape)
(2008)
C2
A learning resource for facilitators, parents, caregivers, and persons with cerebral palsy | Version 1 - Released March 2008
GETTING TO KNOW CEREBRAL PALSY: Module 3 - Positioning Your Child
Hambisela - Towards Excellence in Therapy for Cerebral Palsy
Cerebral Palsy Association (Eastern Cape)
(2008)
C2
A learning resource for facilitators, parents, caregivers, and persons with cerebral palsy | Version 1 - Released March 2008
A learning resource for facilitators, parents, caregivers, and persons with cerebral palsy | Version 1 - Released March 2008
GETTING TO KNOW CEREBRAL PALSY: Module 5 - Everyday Activities
Hambisela - Towards Excellence in Therapy for Cerebral Palsy
Cerebral Palsy Association (Eastern Cape)
(2008)
C2
A learning resource for facilitators, parents, caregivers, and persons with cerebral palsy | Version 1 - Released March 2008
GETTING TO KNOW CEREBRAL PALSY: Module 6 - Feeding Your Child
Hambisela - Towards Excellence in Therapy for Cerebral Palsy
Cerebral Palsy Association (Eastern Cape)
(2008)
C2
A learning resource for facilitators, parents, caregivers, and persons with cerebral palsy | Version 2 - Released November 2009
GETTING TO KNOW CEREBRAL PALSY: Module 7 - Play
Hambisela - Towards Excellence in Therapy for Cerebral Palsy
Cerebral Palsy Association (Eastern Cape)
(2008)
C2
A learning resource for facilitators, parents, caregivers, and persons with cerebral palsy | Version 1 - Released March 2008
Heart failure (HF) is a global public health concern with disproportionate socioeconomic, morbidity and mortality burden on low- and middle-income countries (LMICs). This review summarises contemporary data on the demographic and clinical characteristics, aetiologies, treatment, economic burden and
...
outcomes of HF in LMICs. Patients with HF in LMICs are younger than those from high-income countries (HICs) and present at advanced stages of the disease. Hypertension, ischaemic heart disease (IHD), cardiomyopathy (CMO), and rheumatic heart disease (RHD) are the leading causes of HF in LMICs. The contribution of infectious diseases to HF remains prominent in many LMICs. Most health facilities in LMICs lack adequate diagnostic tools for HF, and the use of evidence-based medical and device therapies is suboptimal. Further, HF in LMICs is associated with prolonged hospital stay and high in-hospital and one-year mortality. Finally, HF has profound economic impact on individual patients who, mostly, have no health insurance, and on societies where patients are young, comprising those who have the greatest potential to contribute to economic productivity.
more
Many low- and middle-income countries (LMICs) are undergoing an epidemiological transition. With an improvement in socioeconomic conditions and an aging population, cardiovascular diseases (CVDs), like cardiac arrhythmias, are expected to increase in these countries. However, there are limited studi
...
es on the epidemiology and management of cardiac arrhythmias in LMICs. This review will highlight the unique challenges and opportunities that these countries face when managing cardiac arrhythmias.
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Examining the infrastructure of the Russian and USA healthcare systems with respect to the management of HIV patients
COVID-19 / SARS-CoV-2 (2019-nCoV)
SARS-CoV-2: a respiratory coronavirus that emerged in late 2019 from live animal markets in Wuhan, China. Bats are the reservoir species.
Therapy for MDR-TB is extremely long, complex and burdensome to both patients and health care systems. A single diagnosis can require two years of treatment, or longer. When treating children, there are significant additional barriers treating child
...
ren with MDR-TB. There is limited data on the pharmacokinetics of second-line TB drugs in children, and almost none are in child-friendly formulations. Nonetheless, there is continued work on second-line drugs to fight MDR-TB. The Sentinel Project has created a complex set of dosing recommendations for administering second-line drugs to children
more
WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention approaches.
HIV drug resistance has been rarely reported among PrEP users who tested HIV positive i
...
n randomized controlled trials or open-label studies. However, PrEP-selected HIV drug resistance could potentially negatively impact the effectiveness of treatment options among PrEP users who acquire HIV, since there is a potential for overlapping resistance profiles between antiretroviral drugs used for both PrEP and first-line antiretroviral therapy.
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4 April 2020
This interim guidance on oxygen sources and distribution strategies for COVID-19 treatment has been adapted from WHO and UNICEF’s technical specifications and guidance for oxygen therapy devices, which is part of the WHO medical devi
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ce technical series. This guidance is intended for health facility administrators, clinical decision-makers, procurement officers, planning officers, biomedical engineers, infrastructure engineers and policy-makers. It describes how to quantify oxygen demand, identify oxygen sources that are available, and select appropriate surge sources to best respond to COVID-19 patients’ needs, especially in low-and-middle income countries.
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These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antiretroviral
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therapy (ART) among people living with HIV who are being treated for tuberculosis.
New recommendations launched today outline key new actions that countries can take to improve the delivery of HIV testing, treatment and care services by providing greater options for differentiated approaches such as, supporting HIV treatment start in the community, ensuring that children are diagnosed and treated early, and that viral load treatment monitoring is more accessible, focused and triggers clinical action
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Drugs & Therapy Perspectives vol.36 (2020) 6
Despite progress in improving antiretroviral therapy (ART) for people with HIV in Malawi, the burden of HIV infections and HIV treatment outcomes among key populations is suboptimal. Client-centered differentiated service delivery approaches may fac
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ilitate addressing HIV prevention and treatment needs of key populations in Malawi.
Methods
De-identified program data routinely collected as part of the LINKAGES project–Malawi were assembled from October 2017 to September 2019. HIV case finding was compared across different testing modalities for each population. Poisson regression was used to estimate the association between testing modalities and ART initiation.
Results
Of the 18 397 people included in analyses, 10 627 (58%) were female sex workers (FSWs), 2219 (12%) were men who have sex with men (MSM), and 4970 (27%) were clients of FSWs. HIV case finding varied by modality and population, with index testing and enhanced peer outreach demonstrating high yield despite reaching relatively few individuals. FSWs who tested positive through risk network referral testing were more likely to initiate ART within 30 days compared with those who tested positive through clinic-based testing (adjusted risk ratio [aRR], 1.50; 95% CI, 1.23–1.82). For MSM, index testing (aRR, 1.45; 95% CI, 1.06–2.00) and testing through a drop-in center (aRR, 1.82; 95% CI, 1.19–2.78) were associated with 30-day ART initiation.
Conclusions
These data suggest that differentiated HIV testing and outreach approaches tailored to the needs of different key populations may facilitate improved ART initiation in Malawi. Achieving 0 new infections by 2030 suggests the need to adapt treatment strategies given individual and structural barriers to treatment for key populations with HIV in high-prevalence settings.
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Combination therapy is a cornerstone of modern malaria treatment, particularly in the context of widespread multidrug resistance. Using two or more antimalarial drugs with different mechanisms simultaneously enhances efficacy, shortens treatment dur
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ation, improves compliance and delays the development of resistance. Artemisinin-based combination therapies (ACTs), such as artemether–lumefantrine, artesunate–amodiaquine and artesunate–sulfadoxine/pyrimethamine, are highly effective in rapidly clearing parasites and reducing gametocyte carriage. They are also generally well tolerated. Non-artemisinin combinations, quinine-based regimens and novel combinations (e.g. piperaquine–dihydroartemisinin) offer alternative therapeutic options, although clinical experience with these remains limited. Although ACTs are the preferred first-line treatment, factors such as cost, local drug resistance patterns, safety during pregnancy and paediatric use must inform implementation and policy decisions.
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