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History, epidemiology and diagnostics of dengue in the American and Brazilian contexts: a review

Souza Salles, T.; T. da Encarnação Sá-Guimarães, E. Seam Lima de Alvarenga et al. (2018) CC

Parasites & Vectors volume 11, Article number: 264 (2018) Dengue creates a staggering epidemiological and economic burden for endemic countries. Without a specific therapy and with a commercial vaccine that presents some problems relative to its full effectiveness, initiatives to improve vector... more

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Discrete typing units of Trypanosoma cruzi: Geographical and biological distribution in the Americas

Veláquez-Ortiz, N.; Herrera, G.; Hernández, C. et al. Scientific Data (2022) CC

Chagas disease caused by Trypanosoma cruzi is a public health issue in Latin America. This highly diverse parasite is divided into at least seven discrete typing units (DTUs) TcI-TcVI and Tcbat. Some DTUs have been associated with geographical distribution in epidemiological scenarios and clinical m... more

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Prevalence of Schistosoma Haematobium Measured by a Mobile Health System in an Unexplored Endemic Region in the Subprefecture of Torrock, Chad

Layaye, D.; E de Bruijn, M.; de Jong, T.; et al. JMIR Publication Advancing Digital Health and Open Science (2019) CC

Schistosoma haematobium is a parasitic digenetic trematode responsible for schistosomiasis (also known as bilharzia). The disease is caused by penetration of the skin by the parasite, spread by intermediate host molluscs in stagnant waters, and can be treated by administration of praziquantel. Schis... more

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Male Genital Schistosomiasis Along the Shoreline of Lake Malawi: Baseline Prevalence and Associated Knowledge, Attitudes and Practices Among Local Fishermen in Mangochi District

Kayuni, S.; Alharbi, M.; Makaula, P. et al frontiers in Public Health (2021) CC

Schistosomiasis is a prevalent parasitic, neglected tropical disease (NTD) affecting over 220 million people globally, especially in sub-Saharan Africa (SSA). The pathology of this disease in terms of intestinal, liver and urinary presentations is well-known, yet its chronic effect on host genitalia... more

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Fact sheet Schistosomiasis

World Health Organization WHO (2014) C_WHO

Schistosomiasis is an acute and chronic parasitic disease caused by blood flukes (trematode worms) of the genus Schistosoma. At least 249 million people required preventive treatment in 2012. Preventive treatment, which should be repeated over a number of years, will reduce and prevent morbidity.

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Asian Schistosomiasis: Current Status and Prospects for Control Leading to Elimination

Gordon, C.; Kurscheid, J.; Williams, G. et al. Multidisciplinary Digital Publishing Institute MDPI (2019) CC

Schistosomiasis is an infectious disease caused by helminth parasites of the genus Schistosoma. Worldwide, an estimated 250 million people are infected with these parasites with the majority of cases occurring in sub-Saharan Africa. Within Asia, three species of Schistosoma cause disease. Schistosom... more

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New hope for leishmaniasis

Drugs for Neglected Diseases initiative DNDi (2022) CC

Leishmaniasis is a climate-sensitive disease. Changes in temperature, rainfall, and humidity can have strong impacts on the sandfly vector, altering their distribution and influencing their survival and population sizes. Increased temperatures shorten vector development time, reduce Leishmania p... more

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Dracunculiasis

Rawla, P.; Jan, A. National Library of Medicine (2022) CC

Dracunculiasis, also known as Guinea-worm disease is a parasitic disease caused by the nematode Dracunculus medinensis. The infection is transmitted to humans by drinking water contaminated with the small crustacean copepods (Cyclops) which contain the larvae of D. medinensis. Humans are the princip... more

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Progress Toward Global Eradication of Dracunculiasis

Hopkins, D.; Weiss, A.; Roy, S. et al. Morbidity and Mortality Weekly Report MMWR; National Libary of Medicine (2020) CC

Dracunculiasis (Guinea worm disease), caused by the parasite Dracunculus medinensis, is traditionally acquired by drinking water containing copepods (water fleas) infected with D. medinensis larvae, but in recent years also appears increasingly to be transmitted by eating fish or other aquatic anima... more

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Echinococcosis Key facts

World Health Organization WHO (2021) C_WHO

Human echinococcosis is a zoonotic disease (a disease that is transmitted to humans from animals) that is caused by parasites, namely tapeworms of the genus Echinococcus.

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Cutaneous Leishmaniasis: Urgent need to develop more effective and user-friendly point-of-care diagnostic tools

DNDi redeLEISH (2022) CC

Leishmaniasis is a complex vector-borne disease involving in its transmission several species of protozoan parasites called Leishmania, a wide variety of animal reservoirs and phlebotomine sandflies vectors. Cutaneous Leishmaniasis (CL) is the most common form of the disease, and its clinical manife... more

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Scabies Key facts

World Health Organization WHO (2020) C_WHO

Human scabies is a parasitic infestation caused by Sarcoptes scabiei var hominis. The microscopic mite burrows into the skin and lays eggs, eventually triggering a host immune response that leads to intense itching and rash. Scabies infestation may be complicated by bacterial infection, leading to t... more

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Epidemiology of human African trypanosomiasis

Franco J, Simarro P, Diarra A, Jannin J (2014) CC

The epidemiology of the disease is mediated by the interaction of the parasite (trypanosome) with the vectors (tsetse flies), as well as with the human and animal hosts within a particular environment. Related to these interactions, the disease is confined in spatially limited areas called “foci�... more

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Leishmania

National Organization for Rare Disorders NORD (2019) CC

Leishmaniasis is an infectious disease caused by protozoan parasites of the genus, Leishmania. Protozoa are microscopic, single-celled organisms. The parasites that cause the disease are transmitted to people through the bites of certain species of infected sand flies.

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Global distribution maps of the leishmaniases

Pigott, D.; Bhatt, S.; Golding, N.; et al. eLife Sciences Publications Ltd. (2014) CC

Each year 1–2 million people are diagnosed with a tropical disease called leishmaniasis, which is caused by single-celled parasites. People are infected when they are bitten by sandflies carrying the parasite, and often develop skin lesions around the bite site. Though mild cases may recover on th... more

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What is Leishmaniasis? An introduction and overview

Appuhamy, R.; Clark, J. (2015) CC

Leishmaniasis is a disease caused by a group of protozoan parasites called Leishmania. It is classified as a Neglected Tropical Disease and affects some of the poorest countries in the world causing 20-30,000 deaths each year. The disease is transmitted through the bite of an infected sandfly and ca... more

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Echinococcosis - English version

World Health Organization WHO (2023) C_WHO

Website last accessed on 09.04.2023 Human echinococcosis is a parasitic disease caused by tapeworms of the genus Echinococcus. More than one million people are affected by echinococcosis.

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Echinococcosis - Arabic version

World Health Organization WHO (2023) C_WHO

Website last accessed on 09.04.2023 Human echinococcosis is a parasitic disease caused by tapeworms of the genus Echinococcus. More than one million people are affected by echinococcosis.

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Salwa S. et al - Leishmaniasis

Salwa, S.; Amaar, A.; Baraa, A. et al (2020) C2

Leishmaniasis is a vector-borne tropical/subtropical disease caused by an intracellular parasite transmitted to humans by sand fly bite. It is endemic in Asia, Africa, the Americas, and the Mediterranean region. Worldwide reports include 1.5–2 million new cases each year, more than 300 million at ... more

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Medical treatment of cystic echinococcosis: systematic review and meta-analysis

Velasco-Tirado, V.; Alonso-Sardón, M.; Lopez-Bernus, A. et al BMC Infectious Diseases (2018) C2

Cystic echinococcosis (CE) is a well-known neglected parasitic disease. However, evidence supporting the four current treatment modalities is inadequate, and treatment options remain controversial. The aim of this work is to analyse the available data to answer clinical questions regarding medical t... more