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Pan American Health Organisation PAHO (2024) C_WHO
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2021 Antibacterial agents in clinical and preclinical development: an overview and analysis

World Health Organization WHO (2022) C_WHO
This report presents an analysis of antibacterial agents in preclinical (third annual review) and clinical (fifth annual review) development. The analysis covers traditional (direct-acting small molecules) and non-traditional antibacterial agents in development worldwide. It evaluates to what extent... more
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Directorate General of Drug Administration,, Ministry of Health and Family Welfare, People's Republic of Bangladesh (2015) C1
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2019 Antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline
recommended

World Health Organization WHO (2019) C_WHO
Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions. Gr... more
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Controlled clinical trails in Tuberculosis

A. Jindani, A. Nunn, D. A. Enarson International Union Against Tuberculosis and Lung Disease (2004)
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Africa CDC Consortium for COVID-19 Vaccine Clinical Trials (CONCVACT)

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
August 2020, The Africa Joint Continental Strategy for COVID-19 is underpinned by the need to limit transmission, prevent deaths and reduce associated harms. Participation by African nations in clinical trials is an essential step to ensure that sufficient data is generated on the safety and efficac... more
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Collabovid

Federal Ministry of Education and Research, Germany (2020) CC
A lot of research articles concerning SARS-CoV-2/COVID-19 are published every day. Many of them, so-called pre-prints, are not reviewed in a professional reviewing process at the time of publication. Others are already reviewed and published in well-known journals. Collabovid helps researchers to id... more
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Experimental Ebola drugs face tough test in war zone

Maxman, A. (2018) C2
Researchers are devising a clinical-trial protocol to test three medicines in Africa's latest outbreak Nature doi: 10.1038/d41586-018-06132-7
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BCG vaccination induces HIV target cell activation in HIV-exposed infants in a randomized trial

M. A. Gasper, A. C. Hesseling, I. Mohar, et al. JCI insight (2017) C2
Clinical Medicine JCI Insight. 2017;2(7):e91963.
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Antibacterial agents in preclinical development: an open access database

World Health Organization WHO (2019) C_WHO
The pre-clinical pipeline shows more innovation and diversity, with 252 agents being developed to treat WHO priority pathogens. However, these products are in the very early stages of development and still need to be proven effective and safe. The optimistic scenario, the report indicates, is for... more
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medRxiv- The preprint server for health sciences
recommended

Cold Spring Harbor Laboratory; BMJ; Yale (2020) C1
Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information. COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv
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WHO guidelines on the use of chest imaging in COVID-19
recommended

World Health Organization WHO (2022) C_WHO
Updated 2022. This guide addresses the care pathway from presentation of the patient to a health facility to patient discharge. It considers different levels of disease severity, from asymptomatic individuals to critically ill patients. Accounting for variations in the benefits and harms of chest im... more
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Use of chest imaging in COVID-19 (Arab Version)
recommended

World Health Organization WHO (2020) C_WHO
This rapid advice guide examines the evidence and makes recommendations for the use of chest imaging in acute care of adult patients with suspected, probable or confirmed COVID-19. Imaging modalities considered are radiography, computed tomography and ultrasound. This guide addresses the care pathwa... more
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COVID-19 vaccine tracker and landscape
recommended

World Health Organization WHO (2022) C_WHO
The COVID-19 vaccine tracker and landscape compiles detailed information of each COVID-19 vaccine candidate in development by closely monitoring their progress through the pipeline. The COVID-19 vaccine tracker: Provides summary tables of COVID-19 vaccine candidates in both clinical and pre-... more
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COVID-19 Vaccine Development and Access Strategy

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
Available in English, French, Portuguese and Arabic Successful immunization of a critical mass of the African population with one or several safe and efficacious COVID-19 vaccines.Key objectives1. Accelerate African involvement in the clinical development of a vaccine. 2. Ensur... more
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Statement on the use of Dexamethasone for severely ill COVID-19 Patients

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
Africa Centers for Disease Control and Prevention (Africa CDC) is aware of the media releases of the preliminary results of a large randomized clinical trial conducted in the United Kingdom, which included dexamethasone, a corticosteroid, as one of the drugs used for the treatment of COVID-19 patien... more
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How are vaccines developed?

World Health Organization WHO (2021) C_WHO
This article is part two in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. This article focuses on the ingredients in a vaccine and the three clinical trial phases. Part three outlines the nex... more
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Tackling Antimicrobial Resistance

EuroHealth Observer European Observatory on Health Systems and Policies Eurostation (2020) C2
The focus of the current quarterly edition of Eurohealth (from the European Observatory on Health Systems and Policies) is Antimicrobial Resistance (AMR) and contains the following articles: • Strengthening implementation of AMR national action plans • Fostering clinical developmen... more
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e-Learning Courses - Global Health Training Centre

The Global Health Network (2019) C1
Our e-learning courses are designed to cover every step, process, and issue that needs to be understood in order to conduct high quality research. Every course is written to be globally applicable, so for all diseases and all regions. They are also highly pragmatic and adaptable. Each course is car... more