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Cardiovascular diseases in Africa in the twenty-first century: Gaps and priorities going forward

Minja, N.W.; Nakagaayi, D.; Aliku, T. et al. Frontiers in Cardiovascular Medicine (2022) CC

In 2015, the United Nations set important targets to reduce premature cardiovascular disease (CVD) deaths by 33% by 2030. Africa disproportionately bears the brunt of CVD burden and has one of the highest risks of dying from non-communicable diseases (NCDs) worldwide. There is currently an epide...miological transition on the continent, where NCDs is projected to outpace communicable diseases within the current decade. Unchecked increases in CVD risk factors have contributed to the growing burden of three major CVDs—hypertension, cardiomyopathies, and atherosclerotic diseasesleading to devastating rates of stroke and heart failure. The highest age standardized disability-adjusted life years (DALYs) due to hypertensive heart disease (HHD) were recorded in Africa. The contributory causes of heart failure are changing—whilst HHD and cardiomyopathies still dominate, ischemic heart disease is rapidly becoming a significant contributor, whilst rheumatic heart disease (RHD) has shown a gradual decline. In a continent where health systems are traditionally geared toward addressing communicable diseases, several gaps exist to adequately meet the growing demand imposed by CVDs. Among these, high-quality research to inform interventions, underfunded health systems with high out-of-pocket costs, limited accessibility and affordability of essential medicines, CVD preventive services, and skill shortages. Overall, the African continent progress toward a third reduction in premature mortality come 2030 is lagging behind. More can be done in the arena of effective policy implementation for risk factor reduction and CVD prevention, increasing health financing and focusing on strengthening primary health care services for prevention and treatment of CVDs, whilst ensuring availability and affordability of quality medicines. Further, investing in systematic country data collection and research outputs will improve the accuracy of the burden of disease data and inform policy adoption on interventions. This review summarizes the current CVD burden, important gaps in cardiovascular medicine in Africa, and further highlights priority areas where efforts could be intensified in the next decade with potential to improve the current rate of progress toward achieving a 33% reduction in CVD mortality. more

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Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever Caused by a Newly Identified Virus Strain, Bundibugyo, Uganda, 2007–2008

Paul Roddy, Natasha Howard, Maria D. Van Kerkhove, et al. (2012) CC

PLoS ONE 7(12): e52986. doi:10.1371/journal.pone.0052986. Opern Access please download from the website

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Changing state of the climate system

Gulev S. K., Thorne P. W. et al. (2021) C2

Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change

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Krisenmanagement - Lehrbuch für den öffentlichen Gesundheitsdienst

Böhm H., D. Cwojdzinski, U. Grote et al. Teichert U., P. Tinnemann (2020) C2

Das Management von Krisen hat in den letzten Jahren erheblich an Bedeutung gewonnen, insbesondere auch im Öffentlichen Gesundheitsdienst (ÖGD). Grundsätzlich liegt die Entscheidungshoheit im Rahmen des Krisenmanagements infektiologischer Gefahrenlagen bei den kommunalen Gesundheitsämtern. Aufgru... more

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Special edition: HIV in MSM

I. Steffens; K. Hagmaier; K. Wilson; et al. Eurosurveillance (Europe’s journal on infectious disease epidemiology, prevention and control); European Centre for Disease Prevention and Control (2015) C2

Eurosurveillance Impact Factor 5.7 June 2015 www.eurosurveillance.org Featuring a series of articles on HIV and STI epidemiology, prevention and control among MSM in Europe

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Antimicrobial movement from agricultural areas to the environment: The missing link

Jackson, J., Kheng Heng, L., Eklund, G. et al. Food and Agriculture Organization (FAO) (2019) C2

A role for nuclear techniques Antimicrobials play a critical role in the treatment of human and animal (aquatic and terrestrial) diseases, which has led to their widespread application and use. Antimicrobial resistance (AMR) is the ability of microorganisms to stop an antibiotic, such as an antimic... more

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Health systems resilience during COVID-19: lessons for building back better

Sagan, A.; E. Webb, M. Mckee et al. World Health Organization WHO (2021) C_WHO

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Burnout Syndrome amongst Medical Students in Cameroon: A Cross-Sectional Analysis of the Determinants in Preclinical and Clinical Students

Njim T., H. Makebe, L. Toukam, et. al. Hindawi Psychiatry Journal (2019) C1

Volume 2019, Article ID 4157574, 7 pages https://doi.org/10.1155/2019/4157574

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Ebola Virus Disease in Children, Sierra Leone, 2014–2015

Fitzgerald, F.; A. Naveed, K. Wing, et al (2016) C_CDC

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Buruli ulcer: wound care and rehabilitation

Frimpong, M.; F. S.Sarfo, M. Sarpong Duah, et al. Dove Medical Press Limited (2016) C1

Buruli ulcer caused by Mycobacterium ulcerans is a neglected tropical disease characterized by extensive ulceration involving predominantly the upper and lower limbs of patients. The disease is common in rural tropical communities in West and Central Africa, where access to proper health care is lim... more

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Das kultursensible Krankenhaus

Maria Droste, Dr. Ali Kemal Gün, Hedwig Kiefer, et al. Beauftragte der Bundesregierung für Migration, Flüchtlinge und Integration Bundeskanzleramt (2021) CC

Ansaätze zur interkulturellen Öffnung. Die von der Bundesbeauftragten für Migration, Flüchtlinge und Integration herausgegebene Publikation „Das kultursensible Krankenhaus“ liegt nun in einer vollständig aktualisierten und überarbeiteten Fassung vor und kann kostenfrei heruntergeladen und ... more

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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC

This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more

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Panduan Penanganan Kanker Kandung Kemih Tipe Urotelial

Umbas, R., S. Hardjowijoto, C.A. Mochtar, et al., Indonesian Urological Association (2014) C1

Guidelines for Therapy and Management of Urothelial Urinary Bladder Cancer

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Panduan Penatalaksanaan Kanker Prostat

Umbas, R., S. Hardjowijoto, C.A. Mochtar, et al., Indonesian Urological Association (2011) C1

Guidelines for Therapy and Management of Prostate Cancer in Indonesia

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Guidelines for control of Tuberculosis in prisons

M. Dara, M. Grzemska, M. E. Kimerling, et al. USAID; ICRC; TBCTA (2009) C1

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Rabies epidemiology, prevention and control in Nigeria: Scoping progress towards elimination

Mshelbwala, P.; Weese, J.; Sanni-Adeniyi, O. et al. PLoS Neglected Tropical diseases (2021) CC

Human rabies remains a significant public health problem in Africa with outbreaks reported in most countries. In Nigeria–the most populous country in Africa–rabies causes a significant public health burden partly due to perennial obstacles to implementing a national prevention and control progra... more

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The Senegal urban reproductive health initiative: a longitudinal program impact evaluation

A. Benson; L. Calhoun; M. Corroon; et al. Elsevier (2018) CC

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New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine
recommended

Lindner A. K.; V. Lejon, M.P. Barrett, et al. (2025) CC

The Lancet Infectious Disease Volume 25, Issue 2e77-e85February 2025

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Isoniazid Prophylactic Therapy for the Prevention of Tuberculosis in HIV Infected Adults: A Systematic Review and Meta- Analysis of Randomized Trials

H. T. Ayele, M. S. M. van Mourik, T. P. A. Debray, et al. PLOS One (2015) CC

PLOS ONE | DOI:10.1371/journal.pone.0142290 November 9, 2015; 1 / 16

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Germanys expanding role in global health

Ilona Kickbusch, Christian Franz, Anna Holzscheiter, Iris Hunger, Albrecht Jahn, Carsten Kö; hler, Oliver Razum, Jean-Olivier Schmidt Lancet 2017; 390: 898– 912 (2017) CC

Germany has become a visible actor in global health in the past 10 years. In this Series paper, we describe how this development complements a broad change in perspective in German foreign policy.

New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine recommended

New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine
recommended