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Issue Brief: Update on TB 2025

The MEDBOX Team (2025) CC
Tuberculosis (TB) remains a significant global health challenge, with an estimated annual death rate of approximately one per 100,000 people in countries with low TB prevalence. Rapid reductions in TB cases and deaths worldwide depend on research breakthroughs, including the development of new vac ... more
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WHO guideline on balanced national controlled medicines policies to ensure medical access and safety

World Health Organization WHO (2025) C_WHO
Access to medicines is essential for attainment of universal health coverage, which is central to achievement of the health-related Sustainable Development Goals. Controlled medicines include those such as opioids, benzodiazepines, barbiturates, amphetamines and others with identified or emergent cl ... more
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Catalyzing solutions for equitable global access and sustainable financing for novel tuberculosis vaccines for adults and adolescents

World Health Organization WHO (2025) C_WHO
This report was developed by the WHO TB Vaccine Accelerator Finance and Access working group, co-led by WHO, Gavi and the Government of South Africa. It sets out the working group’s shared vision for equitable access to novel TB vaccines and will advance a shared understanding of the current lands ... more
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Global tuberculosis report 2025
recommended

World Health Organization WHO (2025) C_WHO
The WHO Global tuberculosis report 2025 provides a comprehensive and up-to-date assessment of the TB epidemic and of progress in prevention, diagnosis and treatment of the disease, at global, regional and country levels. This is done in the context of global TB commitments, strategies and targets. ... more
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Use of pre-exposure prophylaxis for HIV among gay and other men who have sex with men

Monteiro, P.V.A.; et al. (2024) CC
Esc Anna Nery 2024;28:e20240093
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National consolidated guidelines for comprehensive HIV prevention, care and treatment

Federal Ministry of Health FMOH, EThiopia (2018)
Continuum of HIV services refers to a comprehensive package of HIV prevention, diagnostic, treatment, care and support services provided for people at risk of infection or living with HIV and their families. This revised edition of the guidelines for use of ARV and opportunistic infection (OI) dru ... more
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Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
recommended
New

Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV ClinicalInfo.gov (2025) C_CDC
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV document is published in an electronic format and updated as relevant changes in prevention and treatment recommendations occur.
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Guidelines for the Prevention and Treatment of Opportunistic Infections in Children With and Exposed to HIV
recommended

ClinicalInfo. gov (2025) C_CDC
Full Guidelines
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Guidelines for the Prevention and Treatment of Opportunistic Infections in Children With and Exposed to HIV. Dosing Charts
recommended
New

ClinicalInfo. gov (2025) C_CDC
Dosing Recommendations for Prevention and Treatment
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National Training Package on Paediatric HIV and AIDS Care and Treatment. Participants Handbook. Module 8: Prevention of HIV in Children

Ministry of Health and Social Welfare, National AIDS Control Programme, Tanzania (2015) C1
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Serious adverse events following treatment of visceral leishmaniasis: A systematic review and meta-analysis

Singh-Phulgenda, S., Dahal, P., Ngu, R. PLOS Neglected Tropical Diseases (2021) C1
Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review of all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported ... more
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WHO recommendations on adolescent health: guidelines approved by the WHO Guidelines Review Committee

World Health Organization (WHO) (2017) C_WHO
This document is meant to respond to the questions:
■ What health interventions should the adolescent receive and when should s/he receive it?
■ What health behaviours should the adolescent practise (or not practise)?
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Appropriation d’un nouveau protocole antipaludéen au Sénégal

Faye S. L., J. L. Ndiaye, S. Ba et. al. SociologieS (2020) C2
Accessed on 03.03.2020 Cet article documente le processus de mise en œuvre du Traitement préventif intermittent TPI), une stratégie de prévention du paludisme dont l’administration est couplée au Programme élargi de vaccination (PEV) dans les services de santé, les réactions des prestat ... more
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Guidelines for Addressing HIV in Humanitarian Settings (IASC)
recommended

Inter-Agency Standing Committee UNAIDS (2010)
These guidelines were developed through an interagency process with participation by United Nations (UN) organiza- tions, nongovernmental organizations, the International Red Cross and Red Crescent Movement and the International Organization for Migration.
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Diagnosis disclosure to adolescents living with HIV in rural Kenya improves antiretroviral therapy adherence and immunologic outcomes: A retrospective cohort study

G. J. Montalto; Fredrick K. Sawe; A. Miruka; et al. Plos One (2017) CC
PLOS ONE | https://doi.org/10.1371/journal.pone.0183180 October 9, 2017
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Guidelines: updated recommendations on HIV prevention, infant diagnosis, antiretroviral initiation and monitoring
recommended

World Health Organization WHO (2021) C_WHO
These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antiretroviral therapy (ART) among people living w ... more
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National clinical guidelines for managment of Diabetes mellitus

Republic of Kenya Ministry of Public Health and Sanitation (2010) CC
The prevalence of chronic non-communicable diseases such as diabetes, cardiovascular diseases and cancers has been on the increase in Kenya in the recent past. This has been occasioned by changes in social and demographic situation in the country. The life expectancy ... more
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Guidelines for Prevention and Management of Common Opportunistic Infections/Malignancies among HIV-Infected Adult and Adolescent

National AIDS Control Organisation, Ministry of Health & Family Welfare , Government of India, (2007) C1