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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Urban Ecosystem-based Adaptation: Regreening Cities to Takle Climate Change

UN Enivronemnt Programme UNEP (2022) CC

Briefing Note 8. Ecosystem-based adaptation (EbA) is a strategy for adapting to the adverse impacts of climate change by harnessing nature and the services it can provide. This strategy is crucial for cities and peri-urban areas, threatened by a multitude of climate hazards and home to more than ha... more

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Setting Up a Cancer Centre: A WHO–IAEA Framework

World Health Organization WHO; International Atomic Energy Agency IAEA (1989) C1

Cancer centres are a major resource in ensuring a comprehensive approach to cancer treatment and its planning. As part of a new roadmap developed by WHO and IAEA to help countries design national cancer control programmes, this publication proposes a framework to develop a cancer centre and/or to st... more

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Best Practices in Water and Sanitation

Dennis Warner, and Christopher Seremet USAID, CRS (2008)

External Link

Ethiopia - Multi-Sectorial Cholera Elimination Plan 2022 - 2028

Government of Ethiopia (2023) C2

The Ethiopia Multi-Sectorial Cholera Elimination Plan (2022-2028) outlines a national strategy to eliminate cholera in Ethiopia by 2028. The plan follows the Global Roadmap to End Cholera by 2030 and is based on six key pillars: Leadership & Coordination, Water, Sanitation & Hygiene (WASH), Surveill... more

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National Family Health Survey (NFHS-5), India, 2019-21: Sikkim

International Institute for Population Sciences (IIPS) and ICF Ministry of Health and Family Welfare (2021) CC

March 2021 This report presents the key findings of the NFHS-5 survey in Sikkim, followed by detailed tables and an appendix on sampling errors. The 2019-21 National Family Health Survey (NFHS-5), the fifth in the NFHS series, provides information on population, health, and nutrition for India and ... more

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Zambia Steps for Non Communicable Risk Factors

Ministry of Health, Zambia Bloomberg Philanthropic; WHO, Path, et al. (2017) CC

Zambia Report for 2017

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India: Targeted Interventions for Truckers, Operational Guidelines

National AIDS Control Organisation (NACO) (2007) C1

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Nutrition of Children and Women in Ghana: A new look at data from the 2008 Ghana Demographic and Health Survey

ICF Macro Measure; DHS (2009) C1

Results from the 2008 Ghana Demographic and Health Survey

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Disability in humanitarian context Views from affected people and field organisations

Handicap International (2015) C2

STUDY - 2015 | Advocacy

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SUMMARY OF FREE ASSESSMENT MEASURES

Center for School Mental Health (CSMH) (2014) C2

The CSMH compiled a list of assessment measures that are in the public domain (free of charge) and available online for clinicians. Below are the recommended measures can be used in school mental health programs to help assess symptoms of clinical disorders (e.g. depression, anxiety, ADHD) an in som... more

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2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke

Powers, W.J.; et al. (2018) C2

A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Guideline DOI: 10.1161/STR.0000000000000158

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Comprehensive Hospital Preparedness Checklist for Coronavirus Disease 2019 (COVID-19)

Centers for Disease Control and Prevention CDC (2020) C_CDC

The following checklist can help hospitals assess and improve their preparedness for responding to a community-wide outbreak of COVID-19. Each hospital will need to adapt this checklist to meet its unique needs and circumstances. This checklist should be used as one of several tools for evaluating c... more

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Abuses and Denial of Aid Endangering Ethnic Minorities in Northern Myanmar

Refugees International (2018) C1

In northern Myanmar, nearly 100,000 people continue to live in displacement camps in Kachin and northern Shan States. Most were first displaced by fighting between the Myanmar military and the Kachin Independence Army in 2011, and many have been displaced multiple times, including in recent months. ... more

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Croatia: Population Movement Emergency Appeal n° MDRHR002 Final Report

International Federation of Red Cross and Red Crescent Societies (2017) C1

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Critical issue module 3 - Children with disabilities

ARC (2009) C1

ARC resource pack - Study material

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WHO recommendations for care of the preterm or low-birth-weight infant
recommended

World Health Organization WHO (2022) C_WHO

The recommendations in this guideline are intended to inform development of national and subnational health policies, clinical protocols and programmatic guides. The target audience includes national and subnational public health policy-makers, implementers and managers of maternal, newborn and chil... more

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Psychosocial Issues for Children and Adolescents in Disasters

Speier, A.H. DHHS Publication (2005) CC

This manual provides information and guidance for individuals concerned with the mental health needs of children who experience major disasters. This background, training, and experience will vary and may include health and mental health professionals, professional and paraprofessional social servic... more

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Impact on Essential Health Services

The Independent Panel (2021) CC

Background paper 8 The Independent Panel for Pandemic Preparedness and Response May 2021

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Bungoma County, Kenya. Multiple Indicator Cluster Survey 2013/14. Final Report

Kenya National Bureau of Statistics, Population Studies and Research Institute and UNICEF (2016)

WHO recommendations for care of the preterm or low-birth-weight infant recommended

WHO recommendations for care of the preterm or low-birth-weight infant
recommended