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Publication Years
3281
3424
382
28
2
1
1
Category
2929
464
273
272
212
99
77
3
Toolboxes
1935
750
328
274
246
189
174
155
145
138
136
130
125
79
71
65
65
63
58
57
47
29
20
18
5
1
Ces recommandations temporaires sont émises à l’intention des États Parties qui font face à une transmission du virus de la mpox (MPXV), y compris, sans que cette liste soit exhaustive, ceux touchés par une transmission communautaire persista
...
nte et ceux où l’on observe des groupes de cas ou des cas sporadiques d’infection par le clade Ib du MPXV liés à des voyages.
more
Lessons learned from recent public health events such as the COVID-19 pandemic, Ebola virus disease, Zika virus disease outbreaks, and other public health threats, including earthquakes and floods,
...
have highlighted the need for countries to continuously develop, strengthen, and maintain capacities required under the International Health Regulations (2005) (IHR (2005)).
Developing capacities for health security in a country requires the engagement of public and private entities across a broad range of sectors, including human and animal health, agriculture, environment, finance, security, emergency management, education, and transportation. The World Health Organization (WHO) is mandated through various resolutions, decisions, and reports of the World Health Assembly, and through the IHR (2005), to provide technical guidance and support to its Member States in developing, strengthening, and maintaining their health systems, including capacities required under the IHR (2005).
For countries to better prevent, prepare for, detect, notify, respond to, and recover from public health emergencies, they must build and maintain IHR core capacities and support the strengthening of health emergency prevention, preparedness, response, and resilience (HEPR) capacities. National Action Plans for Health Security (NAPHS), as capacity development plans, provide the tasks and resources needed to ensure adequate capacities are in place to prevent, detect, respond to, and recover from public health events in a sustainable manner. Investing in the resilience of these capacities within national health systems at national and local levels not only improves national health security but also helps safeguard economic, social, and political developments.
more
La gravité de la récente situation épidémiologique en Amérique latine, marquee par la co-circulation des virus de la dengue, du chikungunya et du Zika, l’émergence d’épizootie de fièvre jaune et l’apparition de cas de microcéphalie et
...
d’autres maladies associées (p. ex. le syndrome de Guillain-Barré) et l’émergence d’épizooties de fièvre jaune ont amené l’Organisation mondiale de la Santé à déclarer une situation d’urgence dans les Amériques en 2016.1 En l’absence d’un traitement spécifique et de vaccins contre la dengue, le chikungunya et le virus Zika, et compte tenu des limitations des stratégies de lutte antivectorielle, l’OMS a préconisé une meilleure utilisation des alternatives disponibles pour améliorer la lutte contre le moustique vecteur Aedes aegypti, ainsi que des activités complémentaires.
more
Measles is one of the most contagious diseases for humans. It is caused by a paramyxovirus virus, manifesting as a febrile rash illness. The incubation period for measles usually is 10–14 days (range 7–23 days) from exposure to symptom onset. In
...
itial symptoms (prodrome) generally consist of fever, malaise, cough, conjunctivitis, and coryza. The characteristic maculopapular rash appears two to four days after onset of the prodrome. Patients are usually contagious from about four days before rash onset until four days after its appearance.
more
Dengue is a mosquito-borne viral disease that has rapidly spread to all regions of WHO in recent years. Dengue virus is transmitted by female mosquitoes mainly of the species Aedes aegypti and, to a lesser extent, Ae. albopictus. These mosquitoes ar
...
e also vectors of chikungunya, yellow fever and Zika viruses. Dengue is widespread throughout the tropics, with local variations in risk influenced by climate parameters as well as social and environmental factors.
more
Responding to a polio outbreak. Guidelines
recommended
The occurrence of a case of wild polio in a previously polio free area as presently in Syria, whether through importation, laboratory accident, or mutation of vaccine virus (VDPV), should be considered a public health emergency, that requires a rapi
...
d and high quality response as utmost priority
more
With a focus on Pakistan and Nigeria’s most vulnerable communities, this report provides insight about the role that community push-back is playing in the transmission of the polio virus and how the Global Polio Eradication Initiative (GPEI) can m
...
itigate these social risks to reach every missed child.
more
The content of these guidelines acknowledges that wasting and undernutrition in HIV-infected children reflect a series of failures within the health system, the home and community and not just a biological process related to virus and host interacti
...
ons.
The guidelines do not cover the feeding of infants 0 to 6 months old, because the specialised care in this age group is already addressed in other WHO guidelines and documents.
more
Travelers planning to conduct humanitarian work in areas where outbreaks of Ebola hemorrhagic fever and Marburg hemorrhagic fever are known to occur need to be familiar with how Ebola virus and Marburg vir
...
us are transmitted
more
Ethical considerations for use of unregistered interventions for Ebola viral disease
World Health Organization
(2014)
West Africa is experiencing the largest, most severe, most complex outbreak of Ebola virus disease in history. On 11 August 2014, WHO convened a consultation where the participants concluded that in the particular context of the current Ebola outbre
...
ak in West Africa, it is ethically acceptable to offer unproven interventions that have shown promising results in the laboratory and in animal models but have not yet been evaluat-
ed for safety and efficacy in humans as potential treatment or prevention
more
Infection prevention and control (IPC) guidance summary
recommended
World Health Organization
(2014)
The summary of the infection prevention and control (IPC) measures is for anyone providing direct and non-direct care to patients with suspected or confirmed Ebola virus disease (EVD) in health-care facilities (HCFs). Essential IPC measures are also
...
included in the Table which can be used as a stand-alone tool.
more
Médecins Sans Frontières (MSF) Guidance App
recommended
For those with smartphones, you can install the free ‘MSF Guidance’ app by the Open Medicine Project from the app store. It includes the MSF guidelines on Ebola and Marburg virus disease. MSF guidance is an easily searchable app with all the la
...
test MSF clinical protocols and essential drug information for medical field workers. All content can be downloaded before mission and accessed at any time.
MSF Guidance for Android devices:
https://play.google.com/store/apps/details?id=org.msf.medical.guidelines&hl=en_US&gl=US
MSF Guidance for Apple devices:
https://apps.apple.com/si/app/msf-medical-guidelines/id1282995934
more
The Directorate General of Epidemiology announces the virtual self-instruction course:
"Vigilance, Prevential and Control of Ebola Virus Disease"
Interim Assessement Report
The EMA review was started by the Agency’s Committee for Medicinal Products for Human Use (CHMP) to support decision-making by health authorities. This first interim report includes information on seven experimental medicines intended for the treatment of people infecte
...
d with the Ebola virus:
BCX4430 (Biocryst);
Brincidofovir (Chimerix);
Favipiravir (Fujifilm Corporation/Toyama);
TKM-100802 (Tekmira);
AVI-7537 (Sarepta);
ZMapp (Leafbio Inc.);
Anti-Ebola F(ab’)2 (Fab’entech).
The amount of information available for the seven treatments is highly variable. For some compounds there is no data from use in human subjects available. A small number of treatments have been administered to patients in the current Ebola outbreak as compassionate use. Finally, there are also medicines included in this review that have already been studied in humans, albeit for the treatment of other viral diseases.
more
Key considerations for the implementation of Community Care Centres
World Health Organization
(2014)
Community Care Centres (CCCs) are small facilities (10 beds maximum), located within the community and run by community health workers. CCCs provide isolation facilities for Ebola patients in order to prevent further transmission of the virus within
...
their households and communities. People with Ebola virus can also receive basic curative and palliative care in these centres in an environment supported by their family and communities. This document describes key principles and main considerations for implementation of a community approach.
more
mBio, Vol. 6 Issue 2, March/April 2015
Available evidence demonstrates that direct patient contact and contact with infectious body fluids are the primary modes for Ebola virus transmission, but this is based on a limited number of studies. In this
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review, the authors address what we know and what we do not know about Ebola virus transmission. They also hypothesize that Ebola viruses have the potential to be respiratory pathogens with primary respiratory spread.
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The only way to prevent future Ebola epidemics of this magnitude is to address the fundamental social and political vulnerabilities that have allowed the virus to flourish, such as weak health systems and local services, poor governance, chronic pov
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erty, and a legacy of conflict and social divisions
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Recovering from the Ebola Crisis
Magdy Martínez-Solimán; Abdoulaye Mar Dieye; Izumi Nakamitsu et al.
United Nations, The World Bank, European Union and African Development Bank
(2015)
Full Report.
In response to a call by the United Nations Secretary-General and the Governments of Guinea, Liberia and Sierra Leone, an international team conducted an Ebola Recovery Assessment. The aim was to contribute towards laying the foundation for short-, medium- and long-term recovery while
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the medical emergency response continues to tackle the epidemic. This report is a contribution to ongoing efforts by the Governments of Guinea, Liberia and Sierra Leone to design their national Ebola virus disease recovery strategies
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The audit was undertaken in order to ascertain whether allocations and donations received directly by the Government of Sierra Leone, in the fight against the Ebola Virus Disease were utilised with due regard to economy and efficiency and that inter
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nal controls were observed accordingly. The audit found that more than US$ 10 million in spending was inadequately documented and US$ 6 million may have been diverted to non-existent or “ghost” workers. The Quote: “It makes one wonder how a serious humanitarian crisis was used as money-making machine,” said Ibrahim Tommy, coordinator for Sierra Leone’s Centre for Accountability and Rule of Law
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When Ebola hit Liberia in 2014, an atmosphere of fear and confusion contributed to the spread of the virus by making people unwilling to come forward for testing and treatment. Oxfam trained and equipped community health volunteers to go door-to-doo
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r, giving information and advice, encouraging anyone showing symptoms to go for tests, and keeping their family members informed about the progress of their treatment. The approach won the trust of communities and helped to slow the spread of the disease. This case study gives an overview of the programme, including aims, results and a personal story.
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