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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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Understanding how temperature shifts could impact infectious disease

RohrI, J.R.; and J. M. Cohen PLOS Biology (2020) CC

Published: November 24, 2020 https://doi.org/10.1371/journal.pbio.3000938 Climate change is expected to have complex effects on infectious diseases, causing some to increase, others to decrease, and many to shift their distributions. There have been several important advances in understanding the ... more

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Technical note: Girls’ Education, Empowerment, and the Elimination of Female Genital Mutilation - arabic version

UN Children's Fund UNICEF (2021) C_UNICEF

The coronavirus disease 2019 (COVID-19) pandemic has created a global and gendered crisis that is compounding existing inequalities and disproportionately affecting girls and women. Emerging evidence from the COVID-19 crisis in 2020 shows school closures, disruptions in essential services and rising... more

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Rooted in Trust: Mali Rumor Bulletins

Internews (2021) CC

Internews’ Rooted In Trust (RiT) Project tracks COVID-19-related rumors circulating among social media users and vulnerable communities in Mali, as well as other countries around the globe. The rumors are used to inform risk communication efforts by humanitarians and public health actors, and to s... more

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Disability considerations for COVID-19 vaccination

World Health Organization WHO; UNICEF (2021) C_WHO

Available in Chinese, English, French, Russian and Spanish; WHO and UNICEF policy brief, 19 April 2021 Persons with disabilities are disproportionately impacted by COVID-19, both directly because of infection, and indirectly because of restrictions to reduce the spread of the virus. Persons with di... more

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On Life Support - A battered health system leaves DRC children at the mercy of killer diseases

UNICEF (2020) C1

ON LIFE SUPPORT3The Democratic Republic of Congo’s Ebola outbreak has been contained, but confl ict and under-development leave over three million children at risk from measles and other killer diseases. The country’s medical services – ill-equipped and under-resourced – are on life support ... more

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Managing stress in the field

International Federation of Red Cross and Red Crescent Societies International Federation of Red Cross and Red Crescent Societies (2009) C1

The nature of humanitarian work has also drastically changed over the last decade. Humanitarian workers have paid dearly in the face of violence and terrorism. Burn out and after-effects of traumatic experiences constitute a major risk for humanitarian workers. After ten years of experience with ... more

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Vaccines and immunization for monkeypox: Interim guidance, 16 November 2022

World Health Organization WHO (2022) C_WHO

The goal of the global outbreak response for monkeypox is to stop human-to-human transmission of monkeypox, with a priority focus on communities at high risk of exposure which may differ according to context, and to effectively use strong public health measures to prevent onward spread of the diseas... more

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Providing palliative care during the COVID-19 pandemic Experiences from Spain

World Health Organization WHO (2020) C_WHO

During theC OVID-19 crisis, the hospital observed a reduction of about 50% in inpatient visits for palliative care. Some patients postponed appointments given the risk of potential infection. Instead of in-person visits, weekly phone calls and remote follow-up were given priority.Palliative care is ... more

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Zika virus disease epidemic: Preparedness planning guide for diseases transmitted by Aedes aegypti and Aedes albopictus

European Centre for Disease Prevention and Control (2016) C1

The threat posed by Zika virus infection highlights the need to reinforce preparedness arrangements for mosquito-borne diseases in EU/EEA countries, especially for pathogens transmitted by Aedes aegypti and Aedes albopictus. The aim of this document is to highlight measures that can effectively red... more

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Socioeconomic inequality in vulnerability to all-cause and cause-specific hospitalisation associated with temperature variability: a time-series study in 1814 Brazilian cities

Rongbin Xu, Qi Zhao, M.S.Z.S. Coelho et al. (2020) CC

The Lancet Planetary Health Volume 4, ISSUE 12, e566-e576, December 01, 2020. Exposure to temperature variability has been associated with increased risk of mortality and morbidity. We aimed to evaluate whether the association between short-term temperature variability and hospitalisation was affect... more

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The political determinants of the cholera outbreak in Yemen

Jonathan Kennedy, Andrew Harmer, David McCoy (2017) CC

The Lancet Global Health, published online 18 August 2017; http://dx.doi.org/10.1016/S2214-109X(17)30332-7 The article "The Political Determinants of the Cholera Outbreak in Yemen" examines how the ongoing civil war has contributed to Yemen’s severe cholera outbreak. The 2017 epidemic was des... more

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Cyclone Shelter Assessment

UN-Habitat (2012) C1

The purpose of this study was to document a technical assessment of a sample of these existing shelters on their functionality, accessibility, operation and management, community perspectives in Myanmar; identify gaps, needs and further the linkages with community-based disaster risk reduction (CDBR... more

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Chronic Obstructive Pulmonary Disease (COPD) - Patient Education; Information

Lareau S.C., Fahy B. et al American Thoracic Society (2019) CC2

The document by the American Thoracic Society provides an overview of Chronic Obstructive Pulmonary Disease (COPD), explaining its causes, such as smoking and environmental factors, symptoms like breathlessness and chronic cough, and diagnostic methods including spirometry. It discusses treatment st... more

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Housing at the forefront of the response to COVID-19: Discussion paper on policy options for Myanmar

UN-HABITAT (2020) C1

Urban poor communities including the homeless, residents of informal settlements, residents at risk of being evicted, Internally Displaced Persons (IDPs), undocumented persons, low-income renters, as well as homeowners are perhaps at greatest risk from both COVID-19 and the response interventions to... more

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Guidance on pooled testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1

The purpose of this document is to provide guidance on the use of pooled sample testing strategy in coronavirus disease (COVID-19) testing laboratories of the African Union Member States for scaling up SARS-CoV-2 nucleic acid testing capacity with the available resources. The current document descr... more

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Shelter Safety Handbook
recommended

The International Federation of Red Cross and Red Crescent Societies IFRC (2011) CC

This handbook presents some basic information on safe construction practices. Its purpose is to provide guidance on choices regarding settlement planning in risky environments, as well as on the building techniques to improve individual shelters. The contents may be used to develop trainings on part... more

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Recommended package of interventions for HIV, viral hepatis and STI prevention, diagnosis, treatment and care for people who inject drugs: policy brief

World Health Organisation (WHO) (2023) C_WHO

HIV, viral hepatitis and STI epidemics, particularly among people who inject drugs and other key populations, continue to be fuelled by laws and policies criminalizing sex work; drug use or possession; diverse forms of gender expression and sexuality; stigma and discrimination; gender discrimination... more

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Frequently asked questions about prevention and control of COVID-19 in prisons and other places of detention

World Health Organization (Europe) (2020) C_WHO

People in prisons and other places of detention live in a closed environment and in close proximity with one another – conditions that facilitate transmission of diseases. They also have a greater underlying burden of disease and worse health conditions than the general population, and frequently ... more

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Haiti: Cholera figures (18 November 2016)

UN Office for the Coordination of Humanitarian Affairs (2016) C1

This document summarizes Haiti's cholera situation as of November 16, 2016. Between January and October 2016, Haiti reported 35,203 new suspected cholera cases (32% increase from 2015) and 369 deaths (56% increase). After Hurricane Matthew, cases rose dramatically, with 52% of new cases concentrated... more

Guidance on pooled testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recommended

Shelter Safety Handbook recommended

Guidance on pooled testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
recommended

Shelter Safety Handbook
recommended