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Protection Response Under the Restrictions of COVID-19

INTERSOS (2020) C1

COVID-19 pandemic has taken the entire world by surprise, creating the greatest global catastrophe since WWII, impacting all spheres of our societies, including health, economy, social protection, as well as security, and human rights. The virus affects people and communities indiscriminately in all... more

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Antimicrobial Resistance (AMR)

Deininger, K. The MEDBOX Team (2023) CC

Issue Brief 31: Antimicrobial resistance (AMR) can occur when viruses, bacteria, parasites and fungi change over time. There is no longer a response to medicines, and the infection treatment gets really difficult which increases the risk of a disesase spread, which can lead to severe health problems... more

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Americas: Population Movement Emergency Appeal n° MDR42004 - Operations Update no. 1, 1 February 2019

International Federation of Red Cross And Red Crescent Societies IFRC (2019)

By December of 2019, an estimated 5.3 million Venezuelans would have left the country, migrating in search of opportunities, health services and an overall search to improve the socio-economic conditions of themselves and their families. This is the largest migration in the history of the Americas. ... more

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Framework for Equitable Allocation of COVID-19 Vaccine

National Academies of Sciences, Engineering, and Medicine (2020) C1

In response to the coronavirus disease 2019 (COVID-19) pandemic and the societal disruption it has brought, national governments and the international community have invested billions of dollars and immense amounts of human resources to develop a safe and effective vaccine in an unprecedented time f... more

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Acute Chagas Disease: New Global Challenges for an Old Neglected Disease

Andrade, D.; Gollob, K.; Dutra, W. PLoS Neglected Tropical diseases (2015) CC

Abstract: Chagas disease is caused by infection with the protozoan Trypanosoma cruzi, and although over 100 years have passed since the discovery of Chagas disease, it still presents an increasing problem for global public health. A plethora of information concerning the chronic phase of human Chaga... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Situation Analysis of Children with Disabilities in Myanmar

UNICEF Myanmar (2016)

The study analyses the current situation of children with disabilities in relation to realizing their rights and accessing basic services, as well as their life experiences in their communities. It also focuses on identifying the barriers created by society that prevent children with disabilities fr... more

Oxfam Water Distribution Manual

Oxfam (2006) CC

Oxfam Water Supply Scheme for Emergencies. This manual is part of a series of guides devised by the Oxfam Public Health Engineering Team to help provide a reliable water supply for populations affected by conflict or natural disaster. Wherever possible, water supplies in emergency conditions should ... more

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The Building Blocks of a Circular Economy: USAID’S Local Systems Approach to Reducing Ocean Plastic Pollution

USAID (2022) CC

Ocean plastic pollution has reached crisis level: every minute, more than an entire garbage truck of plastic makes its way into the world’s oceans—roughly 11 million metric tons annually. While plastic waste presents an immediate threat to marine wildlife and ecosystems, this global challenge al... more

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Guidelines for the use of antibiotics in production animals: Cattle, pigs, sheep and goats

The Swedish Veterinary Association SVS (2017) C2

In 1998 the Swedish Veterinary Association decided to adopt a general policy for the use of antibiotics in animals. Since then specifi c policies for the use of antibiotics in dogs and cats have been adopted and in 2011 Guidelines for the use of Antibiotics in Production animals – Cattle and Pigs,... more

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Is climate change the biggest threat of the 21st century? Film

Medical Peace Work (2019) CC

The world’s climate is changing. There is scientific consensus that since 1980 global temperatures have increased by almost 1°C. Most people experience climate change through extreme weather events, new and re-emerging infectious disease, and the long term effects of sea level rise, impoverishmen... more

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Rapid Evaluation of the Medicines Registration System in Benin

Diadié Maïga, Bedel Evi, Angélique Gbaguidi USAID, SIAPS (2016) C_WHO

The primary role of Benin’s Department of Pharmacy and Medicines (DPMED) is to develop and apply the national pharmaceutical policy. The main objective of this policy is to ensure the availability and accessibility of quality medicines for the population. To fulfill its mandate, DPMED aims to stre... more

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The Impact of Explosive Weapons in Ukraine – Focus on hard-to-reach areas

Handicap International (2024) CC

When explosive weapons are used in populated areas, they have direct and indirect impacts on the provision of services, community cohesion, humanitarian access, regular support for basic needs, physical safety, mental health and psychological well-being, as well as other social and economic impac... more

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Safe consultations with survivors of violence against women and girls

UN Women (2022) C_WHO

One of the principles underpinning the delivery of all essential services and coordination of those services is the “survivor-centered approach”, which places the human rights, needs, and wishes of women and girl survivors at the centre of service delivery. A key challenge faced by many entit... more

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The impact of the COVID-19 pandemic on Syrians: An Analysis by Syrian civil society

Half of Syria (2020) C2

A comprehensive briefing by Half of Syria April 2020 A comprehensive briefing on the critical challenges of the COVID-19 pandemic to Syrians, as reported by Syrian civil society organisations. These challenges have been collated following extensive interviews with the teams of member and partner... more

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A Second Revolution: Thirty years of child rights, and the unfinished agenda. Summary

Terre des hommes, Save the Children, Plan International, SOS Children's Villages International, World Vision, ChildFund Alliance (2019) C2

The report showed commitments made three decades ago to protect the rights of children remain unfulfilled for millions. Violence still affects countless children. Discrimination based on age, gender, disability, sexual orientation and religion harms children worldwide. The UN Convention on the Ri... more

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Cochrane COVID-19 Study Register

Cochrane Library (2020) CC

The aim of the register is to support rapid evidence synthesis by all systematic review producers, including Cochrane's work on Rapid Reviews in response to COVID-19. The register helps systematic reviewers prioritize topics, identify available evidence, and produce urgently needed reviews for front... more

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Malaria Vaccines: Progress to Date

Stanisic, D. I.; and M.F. Good (2023) CC2

BioDrugs. 2023 Sep 20;37(6):737–756. doi: 10.1007/s40259-023-00623-4 There are many malaria vaccine candidates in development, with more than a dozen of these in clinical development. RTS,S/AS01 (also known as Mosquirix) is the most advanced malaria vaccine and was shown to have modest efficacy ... more

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Environmental Determinants of Cardiovascular Disease

Bhatnagar, A. Circulation Research (2018) CC

Many features of the environment have been found to exert an important influence on cardiovascular disease (CVD) risk, progression, and severity. Changes in the environment due to migration to different geographic locations, modifications in lifestyle choices, and shifts in social policies and cultu... more

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Leishmaniasis in Eurasia and Africa: geographical distribution of vector species and pathogens

Cunze, S.; Kochmann, J.; Koch, L. et al. Royal Society open Science (2019) CC

Leishmaniasis is a vector-borne disease with a broad global distribution and an increasing number of recorded cases worldwide. However, it is still one of the world's most neglected diseases. Over the last decades, the disease has been found to expand geographically with a global increase of cases o... more