This diagnostic and treatment manual is designed for use by medical professionals involved in curative care at the dispensary and hospital levels. We have tried to respond in the simplest and most practical way possible to the questions and problems faced by field medical staff, using the accumulate...d field experience of Médecins Sans Frontières, the recommendations of reference organizations such as the World Health Organization (WHO) and specialized works in each field.
Available in English, French, Spanish and Arabic
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9th edition; 4th English edition 2020
Este guia de treinamento explica como identificar os sinais e sintomas das doenças tropicais negligenciadas da pele por meio de suas características visíveis. Contém ainda informações sobre métodos de diagnóstico e manejo de problemas cutâneos comuns que os profissionais de saúde da linha ...de frente podem encontrar.
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En la presente guía de capacitación se explica cómo reconocer los signos y los síntomas de las enfermedades tropicales desatendidas de la piel a partir de sus características visibles. También contiene información sobre cómo diagnosticar y tratar los problemas frecuentes de la piel que puede... encontrar el personal de salud de primera línea.
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La prueba cutánea de la tuberculina le indicará si alguna vez ha tenido los microbios de la tuberculosis (TB) en el cuerpo.
Clinical Guidelines. Diagnosis and Treatment Manual.
Buruli ulcer is caused by infection with Mycobacterium ulcerans. The disease is reported in more than 33 countries worldwide, but only about half of these countries regularly report data to WHO; most cases are reported from subregions of West and Central Africa. The mode of transmission is not known....
About half of those affected are children aged under 15 years; there is no gender difference. Diagnosis is based mainly on clinical and epidemiological characteristics. Of the four methods used for laboratory confirmation (microscopy, polymerase chain reaction (PCR), histopathology and culture), PCR is the most rapid and widely used. Other rapid methods for detection of mycolactone in lesions from suspected cases, such as fluorescent thin-layer chromatography, are under evaluation in four countries in Africa.
Research to develop point-of-care tests is in progress. Treatment of Buruli ulcer comprises 8 weeks of combined antibiotics (rifampicin and clarithromycin). Complementary therapies such as wound care, skin graft and prevention of disability are needed in some cases to ensure full recovery.
The target set by the World Health Organization (WHO) for control of Buruli ulcer is for countries to achieve a rate of case confirmation by PCR of at least 70%. All endemic countries have at least one PCR facility to support confirmation of cases. However, most countries in the WHO African Region have not been able to reach the target, and the rate of case confirmation has been declining
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Chapters
0:00 Introduction
0.27 Causes of Dengue Fever
1:09 Signs and Symptoms of Dengue Fever
2:30 Dengue Hemorrhagic Fever
3:53 Diagnosis of Dengue Fever
4:10 Treatment of Dengue Fever
Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically beg...in three to fourteen days after infection. This may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash.Recovery generally takes two to seven days. In a small proportion of cases, the disease develops into the life-threatening dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where dangerously low blood pressure occurs.
Dengue is spread by several species of mosquito of the Aedes type, principally A. aegypti.The virus has five different types;infection with one type usually gives lifelong immunity to that type, but only short-term immunity to the others. Subsequent infection with a different type increases the risk of severe complications. A number of tests are available to confirm the diagnosis including detecting antibodies to the virus or its RNA.
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Schistosomiasis, also known as Bilharzia, is an infection caused by a parasitic worm that lives in fresh water in subtropical and tropical regions. Schistosomiasis is second only to malaria as the most devastating parasitic disease. The parasites that cause schistosomiasis live in certain types of f...reshwater snails. The infectious form, known as cercariae, emerge from the snail and then contaminate the water. People become infected when their skin comes into contact with the contaminated freshwater. Most human infections are caused by Schistosoma mansoni, Schistosoma haematobium, or Schistosoma japonicum.
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Guillain-Barre Syndrome (GBS) is an acute autoimmune polyradiculoneuropathy that often follows an antecedent infection. Leishmaniasis is a zoonosis due to a flagellate protozoan of the Leishmania genus and transmitted by the sandfly. Here we report a 15 years old teenager who presented with an ascen...ding installation of the motor deficit in three weeks associated with dysphonia and swallowing disorders. The physical examination showed a flaccid proximo-distal quadriparesis, akinesthesia, apallesthesia and cutaneous lesions on the forehead, wrist and calf that appeared two months earlier. The HIV serology was negative and cerebrospinal fluid examination was normal. The electroneuromyography showed a reduction in motor and sensitive amplitudes with an increase in distal latencies and F waves in the upper limbs and segmental and focal conduction blocks. Parasitological examination of the dermal juice around the edges of the skin lesions revealed amastigote forms of leishmaniasis. The evolution was favorable with only symptomatic treatment.
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Scabies is caused by Sarcoptes scabiei, a mite which lays its eggs under the surface of your skin and reproduces. When the eggs hatch, mites crawl out onto your skin and make new burrows.
The mites can be difficult to identify and may be confused with pubic lice as both conditions cause itching in ...the genital area.
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Human scabies is caused by an infestation of the skin by the human itch mite (Sarcoptes scabiei var. hominis). The microscopic scabies mite burrows into the upper layer of the skin where it lives and lays its eggs.
Scabies is found worldwide and affects people of all races and social classes. Scabi...es can spread rapidly under crowded conditions where close body and skin contact is frequent. Institutions such as nursing homes, extended-care facilities and prisons are often sites of scabies outbreaks. Child care facilities also are a common site of scabies infestations.
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Scabies is a contagious skin condition caused by the mite Sarcoptes scabiei which burrows into the skin and causes severe itching. Scabies is transmitted by direct skin-to-skin contact or indirectly by contact with contaminated material (fomites). This condition is often challenging to diagnose as m...any patients may have only subtle symptoms. However, other patients may present with the classic history of exposure, severe pruritis that is worse at night, and reference to other individuals with similar symptoms. This activity reviews the evaluation and treatment of scabies and highlights the role of the interprofessional team in managing patients with this condition.
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Scabies is an itchy skin condition caused by a tiny burrowing mite. This eight-legged bug is so small which makes it hard to see on the skin. Approximately 300 million cases of scabies are reported worldwide each year.
Leishmaniasis is still considered to be a global health problem, which spreads in most countries in the world. Leishmania is an intracellular obligate protistan parasite that causes different clinical symptoms in infected humans and other animals. There are clinically different types of the disease ...including: visceral, cutaneous or muco-cutaneous leishmaniasis. Approximately, two million new infections occurring annually; 0.7 to 1.2 million cases are recorded with cutaneous leishmaniasis and 200,000–400,000 cases return for visceral leishmaniasis. However, Cutaneous leishmaniasis considers one of uncontrolled wobbling endemic diseases, especially in Iraq, which occurs at the skin to cause a dermal lesion. Usually, the lesion is spontaneously healed to leave a colorless depressed scar and permanent immunity.
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Skin-related neglected tropical diseases, or “skin NTDs”, are historically neglected because active case detection, individual case management, significant resources and intensive effort are required to control, eliminate and eradicate them. Integrated control and management of skin NTDs offers ...a pathway to overcome some of these past challenges.
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Buruli ulcer (BU) is a bacterial skin infection that is caused by Mycobacterium ulcerans and mainly affects people who reside in the rural areas of Africa and in suburban and beach resort communities in Australia.
Although air pollution is well known to be harmful to the lung and airways, it can also damage most other organ systems of the body. It is estimated that about 500,000 lung cancer deaths and 1.6 million COPD deaths can be attributed to air pollution, but air pollution may also account for 19% of all... cardiovascular deaths and 21% of all stroke deaths. Air pollution has been linked to other malignancies, such as bladder cancer and childhood leukemia. Lung development in childhood is stymied with exposure to air pollutants, and poor lung development in children predicts lung impairment in adults. Air pollution is associated with reduced cognitive function and increased risk of dementia. Particulate matter in the air (particulate matter with an aerodynamic diameter < 2.5 μm) is associated with delayed psychomotor development and lower child intelligence. Studies link air pollution with diabetes mellitus prevalence, morbidity, and mortality. Pollution affects the immune system and is associated with allergic rhinitis, allergic sensitization, and autoimmunity. It is also associated with osteoporosis and bone fractures, conjunctivitis, dry eye disease, blepharitis, inflammatory bowel disease, increased intravascular coagulation, and decreased glomerular filtration rate. Atopic and urticarial skin disease, acne, and skin aging are linked to air pollution. Air pollution is controllable and, therefore, many of these adverse health effects can be prevented.
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Smallpox eradication was certified in 1980. Mpox has been endemic in Central and West African countries since it was first detected in 1958 . It is a zoonosis; cases are often found close to tropical rainforests where various animals carry the orthopoxvirus that causes the disease. In endemic countr...ies, most mpox infections in humans result from a primary animal-to-human transmission. Human-to-human transmission can result from close contact with respiratory secretions, skin lesions of an infected person, or recently contaminated objects. Transmission can also occur via the placenta from mother to fetus or through close contact during and after birth.
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The World Health Organization (WHO) organized the first global meeting on skin-related neglected tropical diseases (skin NTDs) at its headquarters in Geneva, Switzerland on 27–31 March 2023. This 5-day hybrid meeting brought together more than 800 global experts, stakeholders and partners from 86 ...countries to consider a wide range of topics and enable participants to share best practices in implementing integrated skin NTD activities at country level. The theme of the meeting was “integration for greater impact”. The agenda is included as Annex 1. The participants are listed in Annex 2. The demographics of participants are shown in Annex 3. A photo gallery is presented as Annex 4. More than 54 oral presentations were made and over 200 posters on the themes related to the sessions were displayed digitally during the course of the 5-day meeting. The book of abstracts (WHO, 2023a) and the webinar recordings (WHO, 2023b) are available on the WHO NTD website
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