PLoS ONE 13(8): e0202499. https://doi.org/10.1371/journal.pone.0202499
This was a school-based cross-sectional study conducted in 2015 among 305 school children aged 7–16 years from two primary schools located in Ilemela and Magu Districts, north-western Tanzania. Single stool and urine samples w...ere collected from each participant and examined for the presence of Schistosoma mansoni eggs, parasite antigen, and parasite DNA using KK thick smears, POC-CCA tests, and real-time PCR, respectively.
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In collaboration with partners, the government of Ethiopia has successfully developed 10 years Hand Hygiene for All (HH4A) costed national roadmap- a country-wide approach to achieving sustainable and universal hand hygiene. On the occasion of the 2022 Global Hand Washing Day event ( Ethiopia is cel...ebrating the event for one month with different sessions), the national HH4A road map launched on the 4th of Nov 2022 in a high-level advocacy event in the presence of higher officials and partners. Action is set mainly on the need for a joint effort to mobilize resources for implementation, monitoring and documenting of lessons and best practices.
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Noncommunicable diseases (NCDs) – chief among them, cardiovascular diseases (heart disease and stroke), cancer, diabetes and chronic respiratory diseases – along with mental health, cause nearly three quarters of deaths in the world. Their drivers are social, environmental, commercial and geneti...c, and their presence is global. Every year 17 million people under the age of 70 die of NCDs, and 86% of them live in low- and middle-income countries (LMICs).
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Noncommunicable diseases (NCDs) – chief among them, cardiovascular diseases (heart disease and stroke), cancer, diabetes and chronic respiratory diseases – cause nearly three-quarters of deaths in the world. Their drivers are social, environmental, commercial and genetic, and their presence is g...lobal. Every year 17 million people under the age of 70 die of NCDs, and 86% of them live in low- and middle-income countries.
Users can explore the data below by country, accessing detailed information on noncommunicable diseases and their key risk factors
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Noncommunicable diseases (NCDs) – chief among them, cardiovascular diseases (heart disease and stroke), cancer, diabetes and chronic respiratory diseases – cause nearly three-quarters of deaths in the world. Their drivers are social, environmental, commercial and genetic, and their presence is g...lobal. Every year 17 million people under the age of 70 die of NCDs, and 86% of them live in low- and middle-income countries.
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Front. Immunol. 12:620657. doi: 10.3389/fimmu.2021.620657.
HIV-1 infection disproportionately affects women in sub-Saharan Africa, where areas of high HIV-1 prevalence and Schistosoma haematobium endemicity largely overlap. Female genital schistosomiasis (FGS), caused most frequently by S. haemato...bium egg deposition in the genital tract, has been associated with prevalent HIV-1 infection in cross-sectional studies. The presence of S. haematobium eggs in genital tissue is also associated with vascularization and the accumulation of CD4+ lymphocytes and macrophages, making the granuloma-associated environment a potential contributor to HIV-1 vulnerability. In addition to modulation of the local cervicovaginal environment, FGS has also been associated with a higher frequency of systemic CD4 T-cells expressing the chemokine receptor CCR5. Tissue-entrapped eggs are also associated with clinically visible FGS-associated manifestations in the cervicovaginal mucosa. FGS lesions may breach the intact cervicovaginal immune barrier and are hypothesized to provide an entry point for HIV-1 infection. However, the underlying mechanism for potential HIV-1 vulnerability in FGS has not been fully characterized and requires further investigation.
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The World Health Organization (WHO) has identified mental health as an integral component of the COVID-19 response. Its rapid assessment of service delivery for mental, neurological and substance use (MNS) disorders during the COVID-19 pandemic, on which this report is based, is the first attempt to... measure the impact of the pandemic on such services at a global level. The data were collected through a web-based survey completed by mental health focal points at ministries of health between June and August 2020. The questionnaire covered the existence and funding of mental health and psychosocial support (MHPSS) plans, the presence and composition of MHPSS coordination platforms, the degree of continuation and causes of disruption of different MNS services, the approaches used to overcome these disruptions, and surveillance mechanisms and research on MNS data.
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AMR is one of the Key priority of the global health security agenda action package, as well as it is one of the commitments of Ministry of Public Health Afghanistan to combat AMR. In Afghanistan because of war and some other political issues the borders of the country are not well secured and well c...ontrolled therefore control of smuggling of medicine is a big challenge in front of the rational use of medicine. Lack of knowledge (professionals and public), poor economic state, conflict of war, presence of remote areas and etc…. are the other main challenges for this to won the battle of combating AMR.
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Putting Human Rights at the Heart of the Response
Topic in Focus: COVID-19 and Women’s Human Rights
15 April 2020
Stay-at-home restrictions and other measures restricting the movement of people contribute to an increase in genderbased violence, a finding confirmed by media reports, official ...statements and information received from OHCHR field presences and human rights defenders in many countries.
Women and girls already in abusive situations are more exposed to increased control and restrictions by their abusers, with little or no recourse to seek support. Hotlines receive reports of women being threatened with being thrown out of their homes, exposed to the infection, or having financial resources and medical aid withheld.
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La enfermedad de Chagas (ECha), resultado de la infección por el Trypanosoma cruzi, afecta varias poblaciones de las
zonas rurales de Suramérica y América Central. En los últimos años la enfermedad ha cobrado importancia epidemiológica no sólo porque se ha incrementado la detección de caso...s, sino por la presencia, en la infección crónica, de cardiopatía, patología de considerable gravedad clínica y cuya aparición aumenta el riesgo de incapacidad y reducción de la expectativa de vida.
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En los últimos cinco años y como parte del ciclo programático humanitario, se han identificado las personas con necesidades en Colombia (anual) en un esfuerzo conjunto de los socios del Equipo Humanitario de País, en coordinación con otras contrapartes del Estado. La afectación histórica de m...illones de personas por diferentes emergencias humanitarias, como consecuencia del conflicto, la violencia y eventos de desastres naturales, ha requerido la presencia e intervención complementaria al Estado, por parte de organizaciones humanitarias tanto nacionales como internacionales. Después de cuatro años de Diálogos de Paz entre el Gobierno y las FARC-EP se dio la firma de un Acuerdo, el cual debía también representar el alivio humanitario en muchas regiones golpeadas; no obstante, el deterioro de la situación humanitaria interna en Colombia, se refleja en más de 5.1 millones de personas con necesidades, como lo podremos evidenciar en este documento.
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Nota científica
24 de abril de 2020
El desarrollo de inmunidad a un patógeno por infección natural es un proceso de varias etapas que suele producirse a lo largo de una o dos semanas. El organismo responde a una infección vírica de forma inmediata a través de una respuesta innata no específ...ica, en la que los macrófagos, los neutrófilos y las células dendríticas frenan el avance del virus y pueden incluso evitar que este provoque síntomas. A esta respuesta no específica le sigue una respuesta adaptativa en la que el organismo genera anticuerpos que se unen específicamente al virus. Estos anticuerpos son las proteínas denominadas inmunoglobulinas. El organismo también genera linfocitos T que reconocen y eliminan las células infectadas por el virus: es lo que se conoce como inmunidad celular. Esta respuesta adaptativa combinada puede eliminar el virus del organismo y, si la respuesta es suficientemente intensa, puede evitar el agravamiento de la enfermedad o la reinfección por el mismo virus. Este proceso se mide a menudo a través de la presencia de anticuerpos en la sangre.
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A atual pandemia de COVID-19 constitui um desafio excepcional e sem precedentes para que as autoridades competentes, com responsabilidades nos sistemas nacionais de controlo da segurança dos alimentosa, possam continuar a desempenhar as suas funções e atividades ...de rotina, de acordo com os regulamentos nacionais e as recomendações internacionais. Em muitos países, os funcionários das autoridades competentes estão, em grande parte, trabalhando a partir de casa, usando o teletrabalho como prática normal, visto que todas as reuniões presenciais foram canceladas ou reagendadas como teleconferências. É um desafio manter, sem interrupção, as atividades normais de rotina, tais como a inspeção das operações do negócio alimentar, a certificação das exportações, o controlo dos alimentos importados, a monitorização e vigilância da segurança da cadeia de abastecimento alimentar, a amostragem e análise dos alimentos, a gestão de incidentes alimentares, o aconselhamento sobre segurança dos alimentose regulamentos para a indústria alimentar, para além da comunicação com o público sobre questões de segurança dos alimentos.
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El objetivo de esta GPC es proporcionar recomendaciones para el tamizaje organizado
del CCR en el territorio nacional, permitiendo el acceso equitativo a medidas de
prevención y detección temprana de la enfermedad con el fin de disminuir la
incidencia y la mortalidad por el CCR en Argentina.... Esta guía está destinada a todos
aquellos trabajadores de la salud que desarrollen actividades de prevención del CCR.
La población objetivo incluye a aquellos individuos de riesgo promedio, sin
antecedentes personales ni familiares de CCR ni adenomas. Sin embargo, aquellos
individuos identificados con presencia de síntomas sospechosos de CCR, individuos
con incremento del riesgo para el desarrollo de esta enfermedad (síndrome de Lynch,
PAF, PAFA, poliposis hamartomatosas, síndrome de poliposis aserrada, EII, etc.) o con
antecedentes de resecciones de pólipos o adenomas, deberán ser priorizados en el
seguimiento o derivados a atención especializada consecuente, según las
recomendaciones vigentes.
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L’enquête a été réalisée dans la Commune de Dori, chef-lieu de la province du Seno dans la Région du Sahel. Suite à la crise sécuritaire qui prévaut au Burkina Faso depuis 2016, la commune de Dori a enregistré 66 7981 personnes déplacées à la date du 30 Avril 2022. Ce chiffre est le p...lus élevé dans la province du Séno. Les déplacées ont été contraints d’abandonner leurs moyens d’existence, font face à la précarité, bénéficient de l’assistance gouvernementale, des acteurs humanitaires et des populations hôtes.
Il s’agit d’une SMART Rapide. Les secteurs/villages ont été sélectionnés par le logiciel ENA en utilisant la probabilité proportionnelle à la taille. Quant aux ménages, ils ont été sélectionnés selon un processus de segmentation et d’échantillonnage aléatoire simple ou systématique.
Les données ont été collectées du 13 au 15 Juin 2022 par 5 équipes composées d’un chef et d’un mesureur chacune. Les équipes ont été supervisées durant toute la collecte. Les paramètres collectés étaient l’âge, le sexe, le poids, la taille, le périmètre brachial et la présence des œdèmes. Trois grappes ont été inaccessibles due aux problèmes sécuritaires et les trois grappes de réserves prévues à cet effet ont été utilisées.
Au total 25 grappes, 245 ménages, et 246 enfants ont été enquêtés. Les résultats montrent une prévalence de la malnutrition aiguë globale de 19,8 % (IC 95 % ; 14,7 - 26,1) selon le rapport poids/taille) et 5,3 % (IC 95 % : 3,0 - 9,1) selon le périmètre brachial. La malnutrition aiguë globale combinée est de 22,4 % (IC 95 % : 17,3 - 28,5).
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L’enquête SMART Rapide a été réalisée dans la commune de Fada N’Gourma, chef-lieu de la province du Gourma dans la région de l’Est. C’est la commune de la région qui accueille le plus de personnes déplacées internes (PDI) depuis le début de la crise sécuritaire (85 574 PDIs à la ...date du 30 avril 2022)1 . Ces déplacées ont pour la plupart abandonnées leurs moyens d’existence et se retrouvent dans la précarité et sous l’assistance humanitaire et des populations hôtes.
La méthodologie SMART Rapide a été utilisé pour l’évaluation. Les secteurs/villages ont été sélectionnés par le logiciel ENA en utilisant la probabilité proportionnelle à la taille.
Quant aux ménages, ils ont été sélectionnés selon un processus de segmentation, d’échantillonnage aléatoire simple ou systématique. Les données ont été collectés du 13 au 15 juin 2022 par cinq équipes composées d’un chef d’équipe et d’un mesureur chacune. Les équipes ont été supervisées durant la collecte par des superviseurs. Les paramètres collectés étaient l’âge, le sexe, le poids, la taille, le périmètre brachial et la présence des œdèmes. Quatre grappes ont été inaccessibles due aux problèmes sécuritaires.
Au total, 24 grappes (avec l’utilisation des grappes de réserve), 235 ménages et 356 enfants ont été couverts. Les résultats montrent une prévalence de la malnutrition aiguë globale de 15,2% (11,2%-20,2%) selon le rapport poids/taille et 7,8% (5,0%-11,9%) selon le périmètre brachial. La malnutrition aiguë globale combinée est de 16,9% (12,9%-22,0%).
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KEY MESSAGES
Always talk to a GBV specialist first to understand what GBV services are available in your area. Some services may take the form of hotlines, a mobile app or other remote support.
Be aware of any other available services in your area. Identify services provided by humanitarian pa...rtners such as health, psychosocial support, shelter and non-food items. Consider services provided by communities such as mosques/ churches, women’s groups and Disability Service Organizations.
Remember your role. Provide a listening ear, free of judgment. Provide accurate, up-to-date information on available services. Let the survivor make their own choices. Know what you can and cannot manage. Even without a GBV actor in your area, there may be other partners, such as a child protection or mental health specialist, who can support survivors that require additional attention and support. Ask the survivor for permission before connecting them to anyone else. Do not force the survivor if s/he says no.
Do not proactively identify or seek out GBV survivors. Be available in case someone asks for support.
Remember your mandate. All humanitarian practitioners are mandated to provide non-judgmental and non-discriminatory support to people in need regardless of: gender, sexual orientation, gender identity, marital status, disability status, age, ethnicity/tribe/race/religion, who perpetrated/committed violence, and the situation in which violence was committed. Use a survivor-centered approach by practicing:
Respect: all actions you take are guided by respect for the survivor’s choices, wishes, rights and dignity.
Safety: the safety of the survivor is the number one priority.
Confidentiality: people have the right to choose to whom they will or will not tell their story. Maintaining confidentiality means not sharing any information to anyone.
Non-discrimination: providing equal and fair treatment to anyone in need of support.
If health services exist, always provide information on what is available. Share what you know, and most importantly explain what you do not. Let the survivor decide if s/he wants to access them. Receiving quality medical care within 72 hours can prevent transmission of sexually transmitted infections (STIs), and within 120 hours can prevent unwanted pregnancy.
Provide the opportunity for people with disabilities to communicate to you without the presence of their caregiver, if wished and does not endanger or create tension in that relationship.
If a man or boy is raped it does not mean he is gay or bisexual. Gender-based violence is based on power, not someone’s sexuality.
Sexual and gender minorities are often at increased risk of harm and violence due to their sexual orientation and/or gender identity. Actively listen and seek to support all survivors.
Anyone can commit an act of gender-based violence including a spouse, intimate partner, family member, caregiver, in-law, stranger, parent or someone who is exchanging money or goods for a sexual act.
Anyone can be a survivor of gender-based violence – this includes, but isn’t limited to, people who are married, elderly individuals or people who engage in sex work.
Protect the identity and safety of a survivor. Do not write down, take pictures or verbally share any personal/identifying information about a survivor or their experience, including with your supervisor. Put phones and computers away to avoid concern that a survivor’s voice is being recorded.
Personal/identifying information includes the survivor’s name, perpetrator(s) name, date of birth, registration number, home address, work address, location where their children go to school, the exact time and place the incident took place etc.
Share general, non-identifying information
To your team or sector partners in an effort to make your program safer.
To your support network when seeking self-care and encouragement.
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Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them.
Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed.
Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species.
Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition.
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This factsheet describes the work and activities of the Center for Disease Control and Prevention (CDC) in Mozambique as well as its impact in this country.