Methodological field approaches for scientists with a basic background in entomology to prepare and implement a yellow fever entomological assessment during outbreaks
The World Health Organization (WHO) Global Status Report on Noncommunicable Diseases 2010 projects that noncommunicable diseases (NCDs) will be responsible for over 44 million deaths during the next decade, representing an increase of about 15% since 2010. Most of these deaths will occur in the WHO ...regions of Africa, South-East Asia and the Eastern Mediterranean. In the African Region alone, NCDs will cause around 3.9 million deaths by 2020.
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Snakebite is a neglected public health problem. Rural populations are frequent victims as they go about their daily food production and animal rearing activities and as they reside in the comfort of their homes. Unfortunatly, many of these snakebite cases go unreported and thus do not appear in offi...cial epidemiological statistics. Health workers often have little or no formal training in the management of snakebite, and appropriate antivenom is rarelay available.
The guidelines for the prevention and clinical management of snakebite in Africa have been developped by the World Health organization Regional Office of Africa with contributions from technical experts. They are meant to assist health workers to improve medical care for snakebite victims; they also serve as a source of information for the general public on issues related to snakes and snakebite.
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This publication describes the first WHO public-benefit Target Product Profiles (TPPs) for snakebite antivenoms. It focuses on antivenoms for treatment of snakebite envenoming in sub-Saharan Africa. Four TPPs are described in the document:
Broad spectrum Pan-African polyvalent antivenoms: products ...that are intended for widespread utility throughout sub-Saharan Africa for treatment of envenoming irrespective of the species of snake causing a bite. Monovalent antivenoms for specific use cases: for products for a single species (or genus) of snake (e.g., boomslangs or carpet viper antivenoms).
Syndromic Pan-African polyvalent antivenoms for neurotoxic envenoming: products that are intended for treatment of envenoming by species whose venoms are neurotoxic. Syndromic Pan-African polyvalent antivenoms for non-neurotoxic envenoming: products for snakebite envenoming where the effects are largely haemorrhagic, necrotic or procoagulant.
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