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The document “Strengthening the global architecture for health emergency prevention, preparedness, response and resilience” presents a report by the Director-General of the World Health Organization (WHO) to the World Health Assembly on global efforts to improve preparedness and response to heal
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th emergencies. It reviews the implementation of the Health Emergency Prevention, Preparedness, Response and Resilience (HEPR) framework and highlights lessons learned from recent crises such as COVID-19. The report describes international initiatives to strengthen global health governance, surveillance systems, laboratory networks, community protection measures, healthcare capacity and access to medical countermeasures like vaccines and diagnostics. It also discusses coordination of emergency responses, support for countries facing outbreaks or humanitarian crises, and the importance of international cooperation. In addition, the report emphasizes the need for sustainable and coordinated financing to strengthen global health security and ensure that countries can better prevent, detect and respond to future health threats.
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The document “Mpox Continental Response Plan 2.0” outlines the strategy developed by the Africa Centres for Disease Control and Prevention (Africa CDC) in collaboration with the World Health Organization (WHO) to respond to the ongoing mpox outbreak across Africa. The plan describes coordinated
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actions to strengthen surveillance, laboratory capacity, case detection and contact tracing in affected countries. It also focuses on improving access to vaccines, diagnostics and treatment, supporting healthcare systems, and enhancing risk communication and community engagement. In addition, the document highlights the importance of regional and international cooperation, resource mobilization and technical support to help African countries control the outbreak and prevent further spread. Overall, the plan serves as a continental framework to guide a coordinated public health response to mpox in Africa.
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The NIAID Pandemic Preparedness Plan describes the strategy of the National Institute of Allergy and Infectious Diseases (NIAID) to strengthen research and development for future pandemic threats. The plan focuses on identifying and studying viruses with the potential to cause epidemics or pandemics
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and developing medical countermeasures such as vaccines, therapeutics and diagnostics. A key concept is the research on “prototype pathogens,” which represent virus families that may cause future outbreaks, allowing scientists to prepare tools and knowledge in advance. The document also outlines the importance of surveillance, epidemiological research, technological innovation, clinical trials and international collaboration to enable a faster and more effective response to emerging infectious diseases. Overall, the plan aims to improve scientific preparedness so that new health threats can be detected earlier and controlled more rapidly.
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PLoS ONE 18(12): e0295920. https://doi.org/10.1371/journal.pone.0295920. PLHIV were largely unaware and sceptical of U = U as the message appeared to contradict
the mainstream HIV prevention clinical guidance.
This guideline document is a publication of the National AIDS & STI Control Program, Ministry of Health
Kenya
medRxiv preprint;https://doi.org/10.64898/2026.02.18.26346597. This model application demonstrates that the sudden cessation of USAID and CDC
commitments in the largest HIV epidemic in the world leads to increased incidence and mortality
and threatens decades of progress in KZN, South Africa. Rest
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oring funding within 12 months
and increasing efficiency of HIV interventions can reestablish KwaZulu Natal province, South
Africa’s trajectory toward EHE goals.
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WHO's Department for HIV, Tuberculosis, Hepatitis and Sexually Transmitted Infections (STIs) has consolidated all existing normative guidance on STIs into a single publication. Structured around 10 chapters that follow the STI prevention and care cascade, the handbook covers primary prevention, synd
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romic management and asymptomatic case identification, diagnostics, treatment, partner management, surveillance, service delivery, and integration within primary health care, community-based clinics, or other platforms (HIV, sexual health, antenatal clinics, etc).
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This document consolidates, for the first time, WHO recommendations on the prevention, testing, treatment and monitoring of hepatitis B and C, and includes testing strategies for hepatitis D. Drawing on a decade of evidence-based guidance issued between 2015 and 2025, it provides a single, practical
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handbook to support global progress toward eliminating viral hepatitis by 2030.
The document also highlights simplified service delivery models that promote decentralization, integration with primary care and related programmes such as HIV and tuberculosis, as well as task sharing and differentiated care to expand access and improve efficiency. It further underscores the need for robust data and monitoring systems to support effective programme implementation.
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The International Federation of Red Cross and Red Crescent Societies (IFRC) is the world’s largest volunteer-based humanitarian network. With our 190 member National Red Cross and Red Crescent Societies worldwide, we are in every community reaching 160.7 million people annually through long-term s
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ervices and development programmes, as well as 110 million people through disaster response and early recovery programmes. We act before, during and after disasters and health emergencies to meet the needs and improve the lives of vulnerable people. We do so with impartiality as to nationality, race, gender, religious beliefs, class and political opinions.
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The document provides guidance from the CDC on conducting an Operational Readiness Review (ORR) within the Public Health Emergency Preparedness (PHEP) cooperative agreement. It outlines the purpose, structure, and evaluation criteria used to assess whether public health systems are prepared to respo
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nd effectively to emergencies. The guidance describes required capabilities, review processes, and documentation expectations, helping jurisdictions demonstrate their readiness and identify areas for improvement in emergency preparedness and response.
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The document is a practical handbook developed by the European Centre for Disease Prevention and Control (ECDC) that provides guidance on how to design, plan, conduct, and evaluate simulation exercises in public health settings. Its main purpose is to help organisations improve their preparedness an
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d response to communicable disease outbreaks by using structured exercises as a training and evaluation tool. The handbook explains different types of exercises, outlines the steps involved in organising them, and highlights the importance of clear objectives, coordination, and evaluation. Overall, it aims to strengthen emergency preparedness by enabling organisations to identify weaknesses, improve collaboration, and enhance their ability to respond effectively to public health crises.
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O documento apresenta o quadro da Organização Mundial da Saúde para a gestão de riscos de emergências de saúde e desastres (Health EDRM). Explica que comunidades em todo o mundo enfrentam uma ampla variedade de perigos — como surtos de doenças infecciosas, desastres naturais e conflitos —
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e enfatiza a necessidade de uma abordagem abrangente e baseada no risco para reduzir seus impactos. O quadro descreve princípios fundamentais como prevenção, preparação, resposta e recuperação, e destaca a importância de sistemas de saúde fortes, colaboração multissetorial e envolvimento da comunidade. Também apresenta componentes centrais como desenvolvimento de políticas, coordenação, força de trabalho, comunicação e infraestrutura. De modo geral, o texto tem como objetivo ajudar os países a fortalecer a resiliência, reduzir riscos à saúde e melhorar sua capacidade de lidar com emergências de forma eficaz.
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This report presents the performance results of 21 household water treatment (HWT) products evaluated in Rounds III and IV of the WHO International Scheme to Evaluate Household Water Treatment Technologies (the Scheme). Released alongside a consolidated overview of findings from Rounds I–II, it re
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presents the third and final report in a series of laboratory-based evaluations of microbial performance. With these latest evaluations, a total of 51 HWT products have been evaluated under the Scheme. The findings equip procurers with the evidence needed to make informed selection of HWT that supports safer drinking water for all.
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Ukraine. Sitrep 2026: Fifth year of war: deepening humanitarian needs and impact on the HIV Response
As the war in Ukraine enters its fifth year, the humanitarian crisis continues to deepen, with profound consequences for access to essential services, including health care.
Modern warfare tactics, including the widespread use of drones and repeated attacks on critical infrastructure, are increasin
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g civilian harm and fundamentally reshaping how health services are delivered, especially in conflict-affected settings.
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Successful retention and re-engagement in HIV care depends largely on the ability of the provider to involve and motivate patients to attend ongoing care
The document presents a strategic framework by the World Health Organization for managing risks related to emergencies and disasters in the health sector. It highlights that such events (such as epidemics, natural disasters, or conflicts) have major impacts on health, healthcare systems, and societa
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l development. The framework proposes a comprehensive and proactive approach based on prevention, preparedness, response, and recovery, while emphasizing the importance of collaboration across different sectors and stakeholders. Its main objective is to reduce health risks, strengthen the resilience of communities and health systems, and improve health security at the global level.
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The document provides practical guidelines for conducting a national disaster risk assessment, developed by the United Nations Office for Disaster Risk Reduction. It emphasizes the importance of understanding disaster risk as a foundation for effective disaster risk management and sustainable develo
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pment. The guidelines outline a structured process that includes preparing and scoping the assessment, conducting risk analysis, and using the results to inform policy and decision-making. They promote a comprehensive, multi-hazard approach that considers vulnerabilities, exposure, and capacities, while encouraging collaboration among governments, experts, and stakeholders. Overall, the document aims to help countries build stronger systems for assessing and managing risks, thereby enhancing resilience and reducing the impacts of disasters.
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Las recomendaciones aquí presentadas fueron elaboradas a partir de una síntesis sistemática de la evidencia disponible y adoptan un enfoque pragmático, orientado a facilitar su aplicación en escenarios clínicos complejos y de alta demanda. Su desarrollo se fundamenta en los principios de la me
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todología GRADE, lo que garantiza transparencia en la evaluación de la evidencia y claridad en la formulación de las recomendaciones.
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International Journal for Parasitology: Drugs and Drug Resistance Volume 28, August 2025, 100602
This review provides innovative insights to circumvent antimalarial drug resistance and diversify malaria therapeutics.
