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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Assessment of Learning Disabilities: Cooperation between Teachers, Psychologists and Parents

Tuija Aro and Timo Ahonen Niilo Mäki Institute (2011) C2

African edition

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Kenya Comprehensive Refugee Programme 2015

UN High Commissioner for Refugees (2015)

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Ethical Decision-Making in Humanitarian Health in Situations of Extreme Violence. Report and Recommendations

Johns Hopkins Bloomberg School of Public Health , Syrian American Medical Society, et al. (2019) C1

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The Cost of Security Risk Management for NGOs

Finucane, C.; European Interagency Security Forum (EISF) (2013) C2

The Cost of Security Risk Management for NGOs explores the costs related to safety and security management for aid programmes. It aims to assist all aid practitioners to determine their risk management expenditure more accurately, and demonstrate an evidence-based approach when presenting this infor... more

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Review of the national tuberculosis programme in Romania

P. de Colombani, V. Hollo, N. Jansen, et al. World Health Organization; European Centre for disease prevention and Control (2015) C_WHO

10–21 March 2014

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Zimbabwe multi-sectoral cholera elimination plan 2018-2028

World Health Organization WHO; Regional Office for Africa; Cholera Secretariat Zimbabwe (2019) C_WHO

The Zimbabwe Multi-Sectoral Cholera Elimination Plan (2018–2028) aims to eradicate cholera by improving water, sanitation, and healthcare infrastructure, strengthening disease surveillance, and expanding oral cholera vaccination (OCV). The strategy focuses on five pillars, including public health ... more

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COVID-19 Pandemic Preparedness and response in Ethiopia. Weekly Bulletin

Ethiopian Public Health Institute (2021) CC

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Multiple first-line therapies as part of the response to antimalarial drug resistance

World Health Organization WHO (2024) C_WHO

Effective malaria case management requires quick access to diagnostics and antimalarial treatments to reduce illness and death. Artemisinin-based combination therapy (ACT) has been essential to malaria treatment since 2001, as it combines artemisinin for rapid parasite reduction with a partner drug ... more

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Bangladesh Demographic and Health Survey 2014. Three Qualitative Studies

Ministry of Health Bangladesh; The DHS Program; ICF International, et al. (2016) C1

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Crisis Standards of Care: A Toolkit for Indicators and Triggers

Dan Hanfling, John Hick, and Clare Stroud Dan Hanfling, John Hick, and Clare Stroud (2013)

(You need free registration to download the book) Disasters and public health emergencies can stress health care systems to the breaking point and disrupt delivery of vital medical services. During such crises, hospitals and long-term care facilities may be without power; trained staff, ambulances,... more

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Implementation and management of contact tracing for Ebola virus disease

World Health Organization (WHO); CDC (2015) C_WHO

The document covers: introduction on contact tracing in the Ebola response; general considerations for contact tracing; case definition; planning and preparation; personnel; implementation, and tools for contact tracing.

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Professional Standards for Protection Work (Arabic Version). بأنشطة الحماية المعايير المهنية الخاصة

International Committee of the Red Cross ICRC (2013) C1

في النزاعات المسلحة وغيرها من حالات العنفالتي تنفذها الجهات الفاعلة في مجالي العمل الإنساني وحقوق الإنسان

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COVID-19 vaccination (Western Cape Edition)

Wesern Cape Government, South Africa (2021) CC

24 May 2021; Guidance for vaccinators on how to store, prepare, draw up and administer COVID-19 vaccines Updated May 2021 · Western Cape Edition Practical Approach to Care Kit: Vaccine

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Hospital Emergency Response Checklist

World Health Organization, Regional Office for Europe (2011)

An all-hazards tool for hospital administrators and emergency managers. The World Health Organization Regional Office for Europe has developed the Hospital emergency response checklist to assist hospital administrators and emergency managers in responding effectively to the most likely disaster sce... more

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Behaviour Change Communication in Emergencies: A Toolikt

UNICEF ROSA (2006)

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Vulnerability and Capacity Assessment Guidelines

IFRC - International Federation of Red Cross Red Cresent Societies (2006)

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Three models of community mental health services In low-income countries

A. Cohen, J. Eaton, B. Radtke, et al. (2011) CC

International Journal of Mental Health Systems December 2011, 5:3 Community mental health programs in low-income countries face a number of challenges. Using a case study methodology developed for this purpose, it is possible to compare programs and begin to assess the effectiveness of diverse serv... more

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Ensuring health security in the African region - Emergency preparedness and response flagship programmes

World Health Organization WHO, Regional Office of Africa (2022) C_WHO

The World Health Organization Regional Office for Africa (WHO AFRO), in accordance with recommendations from various WHO committees, has developed three flagship programmes to support Member States in the African region to prepare for, detect and respond to public health emergencies. They are the re... more

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LESOTHO: PHC REVITALISATION ACTION PLAN 2011-2017

Ministry of Health and Social Welfare (MoHSS), Kingdom of Lesotho (2011) C2