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Combination of two or more antipsychotic medications for psychotic disorders

World Health Organization WHO (2012) C_WHO
Q2: In individuals with psychotic disorders (including schizophrenia), is the use of two or more antipsychotic medications concurrently more effective and safer than the use of one antipsychotic only?
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Physical activity. Mental Health GAP resources.

World Health Organization WHO (2012) C_WHO
Advice on physical activity should be encouraged as part of treatment for adults with depressive episode/disorder with inactive lifestyles. In moderate and severe depression, this intervention should be considered as adjunct to antidepressants or brief structured psychological treatments.
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National guidelines for the use of pediatric antiretroviral therapy in Cambodia

National Center for HIVAIDS, Dermatology and STD, Cambodia Ministry of Health (2011) CC
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NATIONAL GUIDELINES FOR COMPREHENSIVE CARE OF PEOPLE LIVING WITH HIV IN RWANDA

Ministry of Health, Rwanda (2011) C2
This guide presents new knowledge and guidelines on the provision of care to persons living with HIV/AIDS, in accordance with the last guidelines of the World Health Organization (WHO) published in 2006 and adapted to the Rwandan national context. It thus responds to the need by the Ministry of Heal... more
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IDF Diabetes Atlas 2021

International Diabetes Federation IDF (2022) C1
10th edition The IDF Diabetes Atlas 10th edition provides detailed information on the estimated and projected prevalence of diabetes, globally, by region, country and territory, for 2021, 2030 and 2045. It draws attention to the growing impact of diabetes across the world and highlights proven and ... more
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National Operational Plan for Scaling up HIV Viral Load Testing
recommended

Ministry of Health and Social Welfare, National AIDS Control Programme, Tanzania (2015) CC
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Antibiotic stewardship interventions in hospitals in low-and middle-income countries: a systematic review

Van Dijck C., Vlieghe E., Cox J.A. Bulletin of the World Health Organization (2018) C_WHO
Objective: To review the effectiveness of antibiotic stewardship interventions in hospitals in low- and middle-income countries.
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IASC Mental Health and Psychosocial Support Minimum Service Package

Inter-Agency Standing Commitee (2022) C2
The MHPSS MSP is an easy-to-follow intersectoral package, which spells out the activities and actions that all humanitarian actors should put in place in all emergencies for an effective MHPSS response. It speaks to different actors at the global, regional, national, and local levels to plan, coordi... more
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A systematic review of historical and current trends in Chagas disease

Álvarez-Hernández D., García-Rodríguez-Arana R., Ortiz-Hernández A. et al. Therapeutic advances in infectious disease (2021) CC
Chagas disease (CD) is caused by Trypanosoma cruzi. When acquired, the disease develops in stages. For diagnosis, laboratory confirmation is required, and an extensive assessment of the patient’s health should be performed. Treatment consists of the administration of trypanocidal drugs, which may... more
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Diagnostics to support the eradication of yaws—Development of two target product profiles

Fongwen, N.; Handley, B.; Martin, D. et al. PLoS Neglected Tropical diseases (2022) CC
Yaws is targeted for eradication by 2030, using a strategy based on mass drug administration (MDA) with azithromycin. New diagnostics are needed to aid eradication. Serology is currently the mainstay for yaws diagnosis; however, inaccuracies associated with current serological tests makes it difficu... more
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Interim Technical Note Treatment of cholera in pregnant women 21 November 2022

World Health Organisation (WHO) (2023) CC
The link between cholera in pregnancy and negative childbirth outcomes has been observed since the 19th century, but there is currently no clear understanding of the extent nor the mechanisms to inform treatment guidelines. The recommendations in this Interim Technical Note are based on current k... more
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Psychosocial Care for Pediatric Cancer. Module 01: Psychosocial assessment

World Health Organisation (WHO) (2023) C_WHO
Advances in the treatment of pediatric cancer have made it possible to expand initiatives beyond cure and cover aspects such as early detection, continuity of treatment and reduction in toxicity. All this has paved the way for a more comprehensive vision of patient care, which means better chances o... more
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Atención psicosocial del cáncer pediátrico. Módulo 01: Evaluación psicosocial

World Health Organisation (WHO) (2023) C_WHO
Los avances en el tratamiento del cáncer pediátrico han permitido ampliar las iniciativas más allá de la curación y abarcar aspectos como la detección precoz, la continuidad del tratamiento y la reducción de su toxicidad. Todo ello ha abierto paso a una visión más integral del cuidado de lo... more
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Strengthening countries’ capacities to adopt and adapt evidence-based guidelines: a handbook for guideline contextualization

World Health Organization WHO (2023) C_WHO
Trustworthy, evidence-based health guidelines form the basis of national policies affecting both patients and health-care workers. Emphasizing the link between robust evidence and people’s trust in their health systems, Dr Hans Henri P. Kluge, WHO Regional Director for Europe said at the launch ev... more
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2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes: Developed by the task force on the management of cardiovascular disease in patients with diabetes of the Eur

Marx, N.; Federici, M.; Schütt, K. et al. European Heart Journal (2023) CC
Patients with diabetes are at increased risk of developing cardiovascular disease (CVD) with its manifestations of coronary artery disease (CAD), heart failure (HF), atrial fibrillation (AF), and stroke, as well as aortic and peripheral artery diseases. In addition, diabetes is a major risk factor f... more
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Standard Treatment Guidelines and Essential Medicines List for South Africa; Primary Healthcare Level 2020 Edition; Department of Health: Republic of South Africa

National Department of Health, South Africa National Department of Health, South Africa (2020) CC2
The "Primary Healthcare Standard Treatment Guidelines and Essential Medicines List" by the South African National Department of Health provides evidence-based guidelines for diagnosing and managing common medical conditions at the primary healthcare level. This document includes treatment protocols ... more
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Barriers and determinants of asthma control in children and adolescents in Africa: a systematic review

Mphahlele, R.E.; Kitchin, O.; Masekela, R. BMJ Open (2021) CC
The article "Barriers and determinants of asthma control in children and adolescents in Africa: a systematic review" analyzes factors contributing to poor asthma control in African youth. Based on studies conducted between 2014 and 2019 in Nigeria, Uganda, and South Africa, the review identifies key... more
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Summary of WHO infection prevention and control guideline for Ebola and Marburg disease: a call for evidence based practice

World Health Organisation (WHO) (2024) C_WHO
This article summarises the process involved in developing the updated guideline and includes an infographic to highlight key IPC recommendations from the guideline, following the patient care pathway from the community to a healthcare facility to discharge.
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Provider-initiated HIV testing and TB screening in the era of universal coverage: Are the right people being reached? A cohort study in Blantyre, Malawi

Mair, L.; Corbett, E. L.; Feasey, H. R. A.; et al. PLOS One (2020) CC2
In a prospective cohort study in Bangwe primary care clinic, Blantyre, Malawi, all adults (18 years or older) presenting with an acute illness were screened for TB symptoms (cough, fever, night sweats, weight loss). Demographic characteristics were linked to exit interview by fingerprint bioidentifi... more
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Prevalence, Etiology, and Outcome of Sepsis among Critically Ill Patients in Malawi

Prin, M.; Onofrey, L.; Purcell, L; et al. (2020) CC2
Most of the global burden of sepsis occurs in low- and middle-income countries (LMICs), but the prevalence and etiology of sepsis in LMICs are not well understood. In particular, the lack of laboratory infrastructure in many LMICs has historically precluded an assessment of the pathogens leading to ... more