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Q4: For people with dementia with associated depression, do antidepressants when compared to placebo/comparator produce benefits/harm in the specified outcomes?
Published: March 28, 2017https://doi.org/10.1371/journal.pmed.1002271 PLoS Med 14(3): e1002271. https://doi.org/10.1371/journal.pmed.1002271
Обобщены результаты региональных исследований распространенности болезни Паркинсона (БП) и заболеваемости ею в России; выявлены основные факторы, определяющие к ... more
Q1: What are the effective maternal mental health interventions to prevent developmental problems in early infancy?

Brief psychosocial interventions

World Health Organization (2012) C_WHO
Q1: Are brief psychosocial interventions for people using cannabis or psychostimulants effective in reducing drug use, dependence and harm from drug use?

Strategies to prevent diversion of opioid substitution treatment medications

European Monitoring Centre for Drugs and Drug Addiction (2016) C2
Perspectives on Drugs
Q 6. Does the provision of sterile injection equipment to injecting drug users reduce injecting related harm? Is advice on ways to reduce drug related harm safe and effective, using an outreach model of service delivery?
информационный листок о курении табака через кальян и последствиях для здоровья
Published: February 23, 2010 https://doi.org/10.1371/journal.pmed.1000235 Volume 7 | Issue 2 | e1000235
Q 12: In children and adolescents with anxiety disorders, what is the effectiveness and safety, considering system issues in low- and middle-income countries, of using pharmacological interventions in non-specialist settings?
(2015) Scoping question: Are antidepressants (specifically, tricyclic antidepressants and selective serotonin reuptake inhibitors) effective and safe in adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective?
Q10: Are antidepressants (Tricyclic antidepressants (TCA), Selective serotonin reuptake inhibitors (SSRIs)) effective and safe in children 6-12 years of age with depressive episode/disorder?
Q9: What is/are the effective and safe interventions to treat somatoform disorders in children and adolescents in non- specialist health settings?
Q7: What is the effectiveness, safety and role of pharmacological and non-pharmacological interventions, within non- specialist health care for children with a diagnosis of Attention-deficit hyperactivity disorder (ADHD)?

Interventions for preventing child abuse

World Health Organization (2012) C_WHO
Q2: What are the effective interventions for preventing child abuse and its mental health consequences?

Behaviour change techniques for promoting mental health

World Health Organization (2012) C_WHO
Q13: What is the effectiveness of behaviour change techniques including life skills education in promoting mental health for children and adolescents?
The number of general health staff skilled in psychological treatment for depression is limited, and learning psychological treatments tends to require considerable training and supervision. Relaxation may be a relatively simple form of psychological treatment. It has been frequently studied in rese ... more
Q6: Is advice on physical activity better (more effective than/as safe as) than treatment as usual in adults with depressive episode/disorder with inactive lifestyles
Q1: In individuals with psychotic disorders (including schizophrenia), are antipsychotic drugs safe and effective?
Q3: In individuals with a first psychotic episode with full remission, how long should antipsychotic drug treatment be continued after remission in order to allow for the best outcomes?