Guidance Document and supporting Resources
PLOS Medicine | https://doi.org/10.1371/journal.pmed.1002514 March 1, 2018
PLOS ONE | https://doi.org/10.1371/journal.pone.0183180 October 9, 2017
Investigación original / Original research
Rev Panam Salud Publica 35(1), 2014
PLOS ONE | https://doi.org/10.1371/journal.pone.0196380 May 15, 2018
PLOS ONE | DOI:10.1371/journal.pone.0172392 February 16, 2017
Single TB and HIV Concept Note Albania 2016-2018 27 April 2015
PLoS Pathogens | www.plospathogens.org 1
February 2012 | Volume 8 | Issue 2 | e100246
1PEP GUIDELINES | 2019 EDITION. The prevalence of both HIV and Hepatitis B is high in South Africa therefore there is a significant risk of acquiring these infections following exposure to infected material. Studies suggest that post- exposure prophylaxis (PEP) with highly active antiretroviral trea...tment (HAART) is highly effective in preventing HIV infection if taken correctly for the full recommended duration of 28 days, and that prophylaxis with Hepatitis B immunoglobulin and vaccination may prevent Hepatitis B infection if given soon after exposure. This update of the Western Cape guidelines for management of potentially infectious exposures is based on current evidence and guidelines issued by the WHO, NDoH and the SA HIV Clinicians Society. The key aim is to promote successful completion of the recommended ART regimen in the 28 day period of therapy, as well as prevent infection with Hepatitis B
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