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Publication Years
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Operational Guidance. This operational guidance provides a structured approach to support countries in sustaining priority services for HIV, viral hepatitis and sexually transmitted infections in the context of reduced external funding. The guidance is intended for national governments, public healt ... more
Panel Recommendations
These guidelines update earlier WHO recommendations to maximize the HIV prevention impact of safe VMMC services and aim to guide the transition to the sustained provision of interventions with a focus on the health and well-being of both adolescent boys and men.
Addressing the threat of antimalarial drug resistance. This year’s report spotlights the growing threat of antimalarial drug resistance. Partial resistance to artemisinin derivatives – the backbone of malaria treatments after failures of chloroquine and sulfadoxine-pyrimethamine​ – has now b ... more
Why this document? The Waste Value Chain Analysis (WVCA) has been designed to help organizations understand local waste value chains, with the aim: To identify gaps and opportunities for improvement of local waste value chains (e.g. where shredding, baling can make recovery profitable) and much more ... more
In response to the growing necessity for accurate and timely information regarding deaths categorized by age, sex, and cause of death, underscored by the profound impact of the COVID-19 pandemic, the Africa Centres for Disease Control and Prevention (Africa CDC) developed the Continental Framework d ... more
The handbook includes evidence-based mental health interventions, drawn from the WHO mhGAP guidelines for mental, neurological, and substance use disorders (3), particularly those listed in the UHC Compendium. Evidencebased interventions to reduce population health-related stigma and discriminatio ... more
This document provides an overview of the updated World Health Organization recommendations for HIV clinical management, which focus on optimizing antiretroviral therapy, preventing vertical transmission, and enhancing tuberculosis prevention among individuals with HIV. These updates are intended to ... more
National Guidelines
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public ... more
A toolkit for health facilities. This toolkit highlights successful differentiated-care approaches implemented in a number of settings and countries in sub-Saharan Africa. The toolkit will be further updated as more experience is gained with these and similar approaches
The Guide on HIV Services for Adolescents Living with HIV (ALHIV) describes organization of adolescent-friendly services to guide heath management teams and health care workers (HCWs) on their roles. It also outlines important aspects to consider when offering comprehensive care to adolescents an ... more
HIV/AIDS Hope Initiative
This report describes efforts in nine countries, supported by the 2gether 4 SRHR programme and other partners, highlighting the results achieved and learning on improving the health and wellbeing of adolescent and young mothers and their families. Key insights include the importance of responsive se ... more
A service guide for site operations
Final Policy
The paper “Artificial Intelligence for Public Health Surveillance in Africa: Applications and Opportunities” examines how artificial intelligence (AI) can improve public health systems across Africa, particularly in low-resource settings. It explores how machine learning and other AI techniques ... more
Populations affected by emergencies are continually at risk of outbreaks of epidemic-prone diseases and other public health hazards. This operational guidance aims to guide decision-making on when and how to implement and strengthen Early Warning Alert and Response (EWAR) in preparation for and resp ... more
This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu ... more
World Health Organization (2018). A practical guide for developing and conducting simulation exercises to test and validate pandemic influenza preparedness plans.