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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Recovering from the Ebola Crisis

Magdy Martínez-Solimán; Abdoulaye Mar Dieye; Izumi Nakamitsu et al. United Nations, The World Bank, European Union and African Development Bank (2015)

Full Report. In response to a call by the United Nations Secretary-General and the Governments of Guinea, Liberia and Sierra Leone, an international team conducted an Ebola Recovery Assessment. The aim was to contribute towards laying the foundation for short-, medium- and long-term recovery while ... more

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Update on COVID-19 vaccination in Syria

World Health Organization WHO; Eastern Mediterranean Region (2021) C_WHO

22 April 2021

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International Guidelines Human Rights and drug policy

M. Stoffregen UNAIDS; World Health Organization; UNDP; et al. (2019) C2

Accessed: 07.11.2019

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Birth defects surveillance: a manual for programme managers

World Health Organization (2014)

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The compound impact of extreme weather events and COVID-19

Walton D., Arrighi J., et al. IFRC - International Federation of Red Cross (2021) C2

From the start of the COVID-19 pandemic until August 2021, extreme weather events have affected at least 139.2 million people and killed at least 17,242 people in at least 433 unique events. These figures are certainly an underestimate, as they do not include estimates of numbers of people affected ... more

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Mass Casualty Management Systems. Strategies and guidelines for building health sector capacity

Health Action in Crisis Word Health Organization (2007)

Disaster planning - organization and administration. 2.Emergency medical services - methods. 3.Emergency medical services - organization and administration. 4.Emergencies. 5.Health policy. 6.Health facilities.7.Guidelines.

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Botswana: Guidelines on Good Manufacturing Practices

Ministry of Health, Gabarone, Botswana (2009) C2

Drug Advisory Board

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National Guidelines for the Use of Antiretroviral Therapy in Adults and Adolescents

National Center for HIVAIDS, Dermatology and STD, Cambodia Ministry of Health (2012) CC

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Philippines: Typhoon Haiyan Situation Report No. 34 (as of 28 January 2014)

OCHA (2014)

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Preparing for and responding to global health emergencies

Cochrane Convenes (2022) C1

Learnings from the COVID-19 evidence response and recommendations for the future. Reflections and recommendations from the evidence synthesis community.

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A framework for mental health and psychosocial support in radiological and nuclear emergencies

World Health Organization (WHO) and InterAgency Standing Committee (IASC) (2020) C_WHO

The health impact of radiological and nuclear emergencies can last for decades. Lessons learned from past radiological and nuclear accidents have demonstrated that the mental health and psychosocial consequences can outweigh the direct physical health impacts of radiation exposure. International rad... more

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Пропаганда актуальности охраны психического здоровья

Alberto Minoletti, Michelle Funk, Natalie Drew et al. World Health Organization (2006) C_WHO

Свод методических рекомендаций по вопросам политики и оказания услуг в области психического здоровья был выпущен под руководством д-ра Michelle Funk, координатора по со... more

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Philippines: A Training Manual for Health Workers on Healthy Lifestyle - Promoting Mental Health (Module 6/6)

WHO and DOH Philippines (2009) C_WHO

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Cross-Border Female Genital Mutilation in East Africa

UNFPA ESARO UNFPA; UNICEF (2022) CC

In East Africa, the trend in cross-border FGM puts at risk the progress achieved in eliminating the practice. The only way we can reach zero FGM by 2030 is by concerted and immediate action to address all aspects of FGM. This policy brief highlights the cross-border dimension of FGM (Ethiopia, Keny... more

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African Union AMR Landmark Report: Voicing African Priorities on the Active Pandemic

Africa Center for Disease Control and Prevention (2024) CC

Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan and the African Union Framework for Antimicrobial Resistance Control 2... more

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Profil Penanggulangan Krisis Kesehatan Kabupaten / Kota Rawan Bencana : Kabupaten Mamasa

Pusat Krisis Kesehatan Ministry of Health of Republic of Indonesia (2016) C1

Profile of health crisis response in potential areas of natural disaster in Indonesia : District of Mamasa

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MSF Guide clinique et thérapeutique
recommended

Médecins sans Frontières MSF (2022) C2

Ce guide clinique et thérapeutique s’adresse aux professionnels de santé impliqués dans les soins curatifs au niveau des dispensaires et des hôpitaux. Nous avons essayé de répondre le plus simplement possible aux questions et problèmes auxquels est confronté le personnel de santé par des ... more

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The World Climate and Security Report 2021

Brock, S.; Barrett, O.L.; Birkman, L.; et al. International Military Council on Climate and Security (2021) CC

The World Climate and Security Report (WCSR) 2021 from the Expert Group of the International Military Council on Climate and Security is a global assessment of the security dimensions of a changing climate and effective means to address them. It is intended to inform timely climate and security po... more

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Working with Individuals, Families and Communities to Improve Maternal and Newborn Health. Module 5

World Health Organization WHO; PAHO Pan American Health Organization, Enfant du Monde (2017) C_WHO

A Toolkit for Implementation. Module 5: Finalizing, monitoring and evaluating the IFC action plan

MSF Guide clinique et thérapeutique recommended

MSF Guide clinique et thérapeutique
recommended