This document provides information and recommendations for action, based on the current available knowledge around monkeypox. It is a first draft which will be updated in light of evolving evidence and additional information as they become available.
Cases of human monkeypox are rarely seen outside of west and central Africa. There are few data regarding viral kinetics or the duration of viral shedding and no licensed treatments. Two oral drugs, brincidofovir and tecovirimat, have been approved for treatment of smallpox and have demonstrated eff...icacy against monkeypox in animals. Our aim was to describe the longitudinal clinical course of monkeypox in a high-income setting, coupled with viral dynamics, and any adverse events related to novel antiviral therapies.
more
Cases of monkeypox (MPX) acquired in the EU have recently been reported in nine EU Member States (Austria, Belgium, France, Germany, Italy, Portugal, Spain, Sweden, and the Netherlands).
Monkeypox (MPX) does not spread easily between people. Human-to-human transmission occurs through close contact ...with infectious material from skin lesions of an infected person, through respiratory droplets in prolonged face-to-face contact, and through fomites. The predominance, in the current outbreak, of diagnosed human MPX cases among men having sex with men (MSM), and the nature of the presenting lesions in some cases, suggest transmission occurred during sexual intercourse
more
Where are the outbreaks? What is monkeypox? Recongnizing monkeypox and more. An update on the monkeypox outbreak including protection, diagnosis, treatment.
جُدري القردة مرضٌ معدٍ مستجدٌ، يسبِّبه فيروس ينتقل إلى البشر من الحيوانات المصابة، التي تكون من القوارض في أغلب الأحيان. ويمكن أن تنتشر العدوى به إلى أشخاص آخرين، إ...ا أن انتقال العدوى من شخص إلى آخر لا يمكن أن يؤدي وحده بسهولة إلى حدوث فاشية. ولا تختلف المظاهر السريرية عن تلك التي شوهدت في الماضي مع الجدري، إلا أنها أقل وخامة. وقد تم استئصال الجدري في جميع أنحاء العالم في عام 1980، إلا أن جُدري القردة لا يزال يظهر بشكل متقطِّع في أجزاءٍ من وسط وغرب أفريقيا بالقرب من الغابات الاستوائية المطيرة. ويتراوح معدل إماتة الحالات في فاشيات جُدري القردة ما بين 1-10%، إلا أنه مع الرعاية الملائمة، يتعافى أغلب المرضى. وتوفر هذه الدورة التدريبية مقدمةً عامةً عن جُدري القردة، وهي موجهة إلى العاملين الصحيين المسؤولين عن الوقاية من مرض
more
Monkeypox is a rare viral zoonotic disease caused by a double stranded DNA virus that belongs to the Orthopoxvirus genus of the Poxviridae family.
There has been a global outbreak of mpox since 2022; this outbreak has been caused by the strain of mpox virus called Clade 2 and has affected around 116 countries worldwide. The current surge in cases is being driven by the rapid spread of a different strain – Clade 1b – which is predominantly ...affecting countries across the African region, particularly DRC, Burundi, Kenya, Uganda and Rwanda [1]. The guidance in this document applies to both Clades of mpox. WHO publishes a dashboard of updated cases globally here. Different Clades and Sub-Clades of mpox behave slightly differently to each other; WHO is monitoring for any significant differences between the Clades, including transmission routes. This guidance will be updated as more information becomes available on this issue.
more
On August 13, 2024, the Africa CDC declared the mpox outbreak a Public Health Emergency of Continental Security (PHECS). The following day, the WHO declared it a Public Health Emergency of International Concern (PHEIC). A coordinated, continent-wide response is essential, co-led by the African Union... (AU) through the Africa CDC and the World Health Organization (WHO), in close collaboration with global partners working under a unified plan, budget, and monitoring framework.
more