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Global report on psoriasis

World Health Organization WHO (2016) C_WHO

Psoriasis, which can involve the skin, nails and joints, is a chronic, painful, disfiguring and disabling noncommunicable disease (NCD) for which there is no cure. It negatively impacts on quality of life. Some of those who suffer from the disease develop chronic, inflammatory arthritis (psoriatic a... more

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Interactive Atlas of Leishmaniasis in the Americas: Clinical Aspects and Differential Diagnosis

Pan American Health Organisation PAHO (2021) C_WHO

In the Region of the Americas, the leishmaniases are a group of diseases caused by various species of Leishmania, which cause a set of clinical syndromes in infected humans that can involve the skin, mucosa, and visceral organs. The spectrum of clinical disease is varied and depends on the interacti... more

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Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions

Phillips, O.; J. Robert, K. Mohamed Abass et al. The Lancet Journal (2020) CC

The Lancet olume 395, ISSUE 10232, P1259-1267, April 18, 2020. Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans infection that damages the skin and subcutis. It is most prevalent in western and central Africa and Australia. Standard antimicrobial treatment with oral rifa... more

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Buruli Ulcer: a Review of the Current Knowledge

Yotsu,R.R.; K. Suzuki, R. E. Simmonds et al. Current Tropical Medicines Report (2018) CC

Current Tropical Medicine Reports (2018) 5:247–256 https://doi.org/10.1007/s40475-018-0166-2 .Purpose of the Review Buruli ulcer (BU) is a necrotizing and disabling cutaneous disease caused by Mycobacterium ulcerans, one of the skin-related neglected tropical diseases (skin NTDs). This article aim... more

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Health Services for Buruli Ulcer Control: Lessons from a Field Study in Ghana

Ackumey, M.M.; C. Kwakye-Maclean, E. O. Ampadu et al. PLoS Neglected Tropical Diseases (2011) CC

PLoS Negl Trop Dis 5(6): e1187. doi:10.1371/journal.pntd.0001187. Buruli ulcer (BU), caused by Mycobacterium ulcerans infection, is a debilitating disease of the skin and underlying tissue which starts as a painless nodule, oedema or plaque and could develop into painful and massive ulcers if left u... more

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Global Epidemiology of Buruli Ulcer, 2010–2017, and Analysis of 2014 WHO Programmatic Targets

Omansen, T.F.; A. Erbowor-Becksen, R. Yotsu, et al. Emerging Infectious Diseases (EID) Journal (2019) C_CDC

Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 25, No. 12, December 2019 2183 Buruli ulcer is a neglected tropical disease caused by Myocobacterium ulcerans; it manifests as a skin lesion, nodule, or ulcer that can be extensive and disabling. To assess the global burden and the progress ... more

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Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer

Scherr, N.; R. Bieri, S.S. Thomas, et al. (2018) CC

Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are... more

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Fact sheet Buruli ulcer (Mycobacterium ulcerans infection)

World Health Organization WHO (2022) C_WHO

Key facts Buruli ulcer is a chronic debilitating disease caused by an environmental Mycobacterium ulcerans. At least 33 countries with tropical, subtropical and temperate climates have reported Buruli ulcer in Africa, South America and Western Pacific regions. It often affects the skin an... more

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Lymphatic filariasis Fact sheet

World Health Organization WHO (2014) C_WHO

Lymphatic filariasis, commonly known as elephantiasis, is a neglected tropical disease. Infection occurs when filarial parasites are transmitted to humans through mosquitoes. When a mosquito with infective stage larvae bites a person, the parasites are deposited on the person’s skin from where ... more

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Impact of human schistosomiasis in sub-Saharan Africa

Adenowo, A.; Oyinloye, B.; Ogunyinka, B. et al. (2015) CC

Human schistosomiasis otherwise called bilharzia, is a fresh- water snail transmitted intravascular debilitating disease resulting from infection by the parasitic dimorphic Schistosoma trematode worms, which lives in the bloodstream of humans. The World Health Organization (WHO) regards the disease ... more

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Prevalence of Schistosoma Haematobium Measured by a Mobile Health System in an Unexplored Endemic Region in the Subprefecture of Torrock, Chad

Layaye, D.; E de Bruijn, M.; de Jong, T.; et al. JMIR Publication Advancing Digital Health and Open Science (2019) CC

Schistosoma haematobium is a parasitic digenetic trematode responsible for schistosomiasis (also known as bilharzia). The disease is caused by penetration of the skin by the parasite, spread by intermediate host molluscs in stagnant waters, and can be treated by administration of praziquantel. Schis... more

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Leishmaniasis

World Health Organization WHO (2023) C_WHO

There are 3 main forms of leishmaniases: visceral (the most serious form because it is almost always fatal without treatment), cutaneous (the most common, usually causing skin ulcers), and mucocutaneous (affecting mouth, nose and throat). Leishmaniasis is caused by protozoan parasites which are tra... more

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Pian: Entrenamiento de trabajadores de la salud a nivel nacional y comunitario sobre ETD de la piel

World Health Organization WHO (2022) C_WHO

Course information Yaws is targeted for eradication by WHO in the 2021-2030 NTD Roadmap. It is therefore crucial to know how to identify cases, design and implement activities to eradicate the disease at the community level. In the context of integration of skin NTDs it is vital to learn to recogn... more

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Conceptual and Operational Framework of Onchocerciasis Elimination with Ivermectin Treatment

World Health Organization WHO; African Programme for Onchocerciasis Control APOC (2010) C_WHO

Onchocerciasis used to be an important public health problem in Africa, with over 37 million people infected and millions suffering from debilitating skin disease, terrible itching, impaired vision and blindness. But the epidemiological situation has improved dramatically over the last two decades.... more

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Exploring the cultural effects of gender on perceptions of cutaneous leishmaniasis: a systematic literature review

Wenning, B., Price, H., Nuwangi, H. et al. Global Health Research and Policy (2022) CC

More than one million people each year become infected by parasites that cause the disease cutaneous leishmaniasis (CL). This disease manifests as one or more skin lesions or ulcers that are slow to heal with variable response rates to drug treatments. Thus far, little attention has been paid to how... more

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Scabies Key facts

World Health Organization WHO (2020) C_WHO

Human scabies is a parasitic infestation caused by Sarcoptes scabiei var hominis. The microscopic mite burrows into the skin and lays eggs, eventually triggering a host immune response that leads to intense itching and rash. Scabies infestation may be complicated by bacterial infection, leading to t... more

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A One-Health Approach to Understanding the Epidemiology of Cutaneous Leishmaniasis

Lana J. T. (2021) C2

American cutaneous leishmaniasis (CL) is a severely understudied and neglected“disease of poverty” widespread throughout Peru. Transmission dynamics of CL are complex, requiring sandfly vectors and mammalian reservoir hosts to maintain the pathogen in a local environment whereby incidental hosts... more

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Global distribution maps of the leishmaniases

Pigott, D.; Bhatt, S.; Golding, N.; et al. eLife Sciences Publications Ltd. (2014) CC

Each year 1–2 million people are diagnosed with a tropical disease called leishmaniasis, which is caused by single-celled parasites. People are infected when they are bitten by sandflies carrying the parasite, and often develop skin lesions around the bite site. Though mild cases may recover on th... more

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Fact Sheet - Lymphatic Filiariasis

World Health Organization WHO (2014) C_WHO

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ANNUAL REPORT NTDs 2023

World Health Organization WHO (2024) C_WHO

This report represents the WHO-supported NTDs program activities and key performances in 2023. It is categorized into three sections: The first section states on the disease targeted for eradication (Guinea worm disease); the second section is on the Preventive Chemotherapy (PC)-NTDs (Trachoma, ... more