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Buruli Ulcer
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Chagas disease (also known as American trypanosomiasis)

World Health Organization WHO (2022) CC
Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi. About 6­–7 million people worldwide are estimated to be infected with T. cruzi. The disease is found mainly in endemic areas of 21 continental Lati... more
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Modelling the climatic suitability of Chagas disease vectors on a global scale

Ebehard, F.; Cunze, S.; Kochmann, J., Klimpel, S. eLife Sciences Publications (2020) CC
eLife 2020;9:e52072. The Triatominae are vectors for Trypanosoma cruzi, the aetiological agent of the neglected tropical Chagas disease. Their distribution stretches across Latin America, with some species occurring outside of the Americas. In particular, the cosmopolitan vector, Triatoma rubrofasci... more
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Chagas Disease For Health Care and Public Health Professionals

Centers for disease control and prevention CDC (2022) CC
Education and information about Chagas Disease, Triatomine bugs, Kissing Bugs, fact sheets, information for special groups, prevention and control, epidemiology, diagnosis and treatment for Health Professionals.
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Trachoma Action Planning TAP

International Coalition for Trachoma Control ICTC (2022) CC
In 2011, ICTC developed a Trachoma Action Plan (TAP) planning guide to support national health officials in endemic countries. This resource was developed to complement the 2020 INSight roadmap by helping countries create specific national plans detailing how they will reach elimination targets in t... more
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The WHO Skin NTDs App shows encouraging results in Kenya study

World Health Organisation WHO (2024) CC
The World Health Organization (WHO) met with Kenya’s Ministry of Health on 25 November 2024 to discuss preliminary results from the first-ever real-world assessment of the WHO Skin NTDs App, powered by two artificial intelligence (AI)-based algorithms. You can download the App for Android and IOS
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Buruli ulcer : management of Mycobacterium ulcerans disease : a manual for health care providers
recommended

J. Buntine; Crofts, K. World Health Organization WHO (2001) CC
This manual is addressed to health care providers dealing with Mycobacterium ulcerans disease (Buruli ulcer). The manual aims to achieve a better understanding of the disease, its clinical presentation and its surgical management. The manual is aimed particularly at district health care providers. A... more
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Mapping the global distribution of Buruli ulcer: a systematic review with evidence consensus

Hope Simpson, Kebede Deribe, Earnest Njih Tabah, Adebayo Peters et al. The Lancet Journal (2019) CC
The Lancet Global Health Volume 7, ISSUE 7, e912-e922, July 01, 2019
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Principaux repères Ulcère de Buruli (infection à Mycobacterium ulcerans)

Organisation Mondiale de la Santé OMS (2022) C_WHO
Principaux faits L’ulcère de Buruli est une infection chronique débilitante causée par la bactérie Mycobacterium ulcerans. L’ulcère de Buruli a été signalé dans au moins 33 pays situés dans des régions au climat tropical, subtropical ou tempéré d’Afrique, d’Amérique ... more
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Buruli ulcer: cured by 8 weeks of oral antibiotics?

Johnson, P.D.R. The Lancet Journal (2020) C1
Phillips and colleagues have shown that rifampicin combined with clarithromycin is non-inferior to RS8, and is safer. This much anticipated trial provides us with a high degree of confidence that an 8-week course of oral rifampicin and clarithromycin should now be the cornerstone of the treatment of... more
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Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions

Phillips, O.; J. Robert, K. Mohamed Abass et al. The Lancet Journal (2020) CC
The Lancet olume 395, ISSUE 10232, P1259-1267, April 18, 2020. Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans infection that damages the skin and subcutis. It is most prevalent in western and central Africa and Australia. Standard antimicrobial treatment with oral rifa... more
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Understanding the transmission of Mycobacterium ulcerans: A step towards controlling Buruli ulcer

Muleta, A.J., R. Lappan, T. P. Stinear, et al. PLoS Neglected Tropical Diseases (2021) CC
August 26, 2021 https://doi.org/10.1371/journal.pntd.0009678
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Report of a WHO–FIND meeting on diagnostics for Buruli ulcer

WHO Tecnical Advisory Group and FIND (2018) CC
The meeting was held from 26 to 27 March 2018 to review and discuss the following topics: Advances and challenges in the use of fTLC, and new approaches to detecting mycolactone using monoclonal antibodies (mAbs). The status of development of rapid diagnostic tests (RDTs) targeting the MUL... more
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Clinical and Laboratory Diagnosis of Buruli Ulcer Disease: A Systematic Review

Sakyi; S.A.; Aboagye, S. Y.; Otchere, I. D. ; et al The Canadian Journal of Infectious Diseases & Medical Microbiology (2016) C1
Volume 2016 | Article ID 5310718 | https://doi.org/10.1155/2016/5310718. Buruli ulcer (BU) is a necrotizing cutaneous infection caused by Mycobacterium ulcerans. Early diagnosis is crucial to prevent morbid effects and misuse of drugs. We review developments in laboratory diagnosis of BU, discuss li... more
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Mandat Réseau de laboratoires et nouveau modèle de programme d’évaluation externe de la qualité des tests de diagnostic par PCR de l’ulcère de Buruli dans la Région africaine de l’OMS

Organisation Mondiale de la Santé OMS (2020) C1
Au total, 18 laboratoires de 13 pays ont participé aux quatre cycles d'AQE : 10 laboratoires de huit pays africains endémiques, dont quatre ont participé aux quatre cycles et trois à trois cycles. Les résultats globaux ont montré que la performance médiane de ces laboratoires s'est amélioré... more
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WHO Meeting on Buruli ulcer and other skin NTDs. Final report.

World Health Organization WHO (2019) C_WHO
The World Health Organization (WHO) convened a meeting of the Technical Advisory Group on Buruli ulcer at its headquarters in Geneva, Switzerland on 25 to 27 March 2019
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Buruli Ulcer: a Review of the Current Knowledge

Yotsu,R.R.; K. Suzuki, R. E. Simmonds et al. Current Tropical Medicines Report (2018) CC
Current Tropical Medicine Reports (2018) 5:247–256 https://doi.org/10.1007/s40475-018-0166-2 .Purpose of the Review Buruli ulcer (BU) is a necrotizing and disabling cutaneous disease caused by Mycobacterium ulcerans, one of the skin-related neglected tropical diseases (skin NTDs). This article aim... more
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Buruli ulcer: wound care and rehabilitation

Frimpong, M.; F. S.Sarfo, M. Sarpong Duah, et al. Dove Medical Press Limited (2016) C1
Buruli ulcer caused by Mycobacterium ulcerans is a neglected tropical disease characterized by extensive ulceration involving predominantly the upper and lower limbs of patients. The disease is common in rural tropical communities in West and Central Africa, where access to proper health care is lim... more
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New generations free of HIV, syphilis, hepatitis B and Chagas disease in the Americas 2018

M. Alonso González; M. B. Mello; L. Sereno; et al. Pan American Health Organization; World Health Organization (Americas); Unicef (2019) C_WHO
- EMTCT Plus
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First meeting of the network on Buruli ulcer PCR laboratories in the WHO African Region Centre Pasteur du Cameroon, Yaoundé, 21–24 October 2019

World Health Organization WHO (2020) CC
Research to develop point-of-care tests is in progress. Treatment of Buruli ulcer comprises 8 weeks of combined antibiotics (rifampicin and clarithromycin). Complementary therapies such as wound care, skin graft and prevention of disability are needed in some cases to ensure full recovery. The targ... more
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Première réunion du réseau de laboratoires PCR pour l’ulcère de buruli dans la région africaine de l’OMS, Centre Pasteur du Cameroun, Yaoundé, 21–24 octobre 2019

Organisation Mondiale de la Santé OMS (2020) CC
L’ulcère de Buruli, une infection causée par Mycobacterium ulcerans, touche plus de 33 pays dans le monde, mais un peu moins de la moitié seulement de ces pays communiquent régulièrement des données sur la maladie à l’OMS.