Представлены литературные данные о полиморфизме психических расстройств в периоде перименопаузы у женщин и о теориях возникновения климактерического синдрома. ...огласно современной гипотезе, мелатонин обладает антигонадотропными свойствами. Резкое снижение уровня мелатонина в организме человека в период полового созревания способствует активации гонадотропной функции гипофиза, выработке фолликул стимулирующего гормона и лютеинизирующего гормона, которые оказывают стимулирующее влияние на половые железы. Участие мелатонина в патогенезе климактерического синдрома изучено недостаточно, а исследования, посвященные использованию мелатонина в качестве лечебного средства, противоречивы. Дальнейшее изучение роли мелатонина в возникновении КС позволит понять возможности психофармакотерапии рассматриваемых расстройств.
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El Programa de acción mundial para superar las brechas en salud mental (mhGAP)1 fue
lanzado por la Organización Mundial de la Salud (OMS) en el año 2008. En 2010, se
lanzó la Guía de Intervención mhGAP (GI‐mhGAP) (1) y se comenzó a aplicar en cinco
países (Etiopía, Jordania, Nigeria, P...anamá y Sierra Leona) dentro de un proyecto
piloto, bajo la supervisión de la OMS. Panamá lo puso en funcionamiento utilizando la
versión española del mhGAP; los otros cuatro países usaron la versión inglesa1.
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as of 12:00 AM, 17 September 2018 - 6:00 AM, 17 September 2018
The purpose of these guidelines is to help health workers to participate in the process of continuous surveillance of safety and efficacy of the pharmaceutical products which are used in clinical practice, thus help to achieve the ultimate goal to make safer and more effective treatment available to... patients. This guideline addresses specifically the issues on what to report, why to report, when to report, where to report and how to report.
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South Africa has faced many challenges over the past two decades, accomplishing profound positive changes in the social structure and government of the nation. This has not yet fully translated into better health for the population, however, particularly the poorest segment. In fact, the p...opulation has lost ground since the 1990s in virtually all important health indicators, leaving South Africa with a high burden of infectious disease.
August 2011, Vol. 101, No. 8 SAMJ
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Desse modo, o Plano de Ação Nacional para Prevenção e Controle da Resistência aos Antimicrobianos do Brasil (PAN-BR) foi elaborado em convergência com os objetivos definidos pela aliança tripartite entre a Organização Mundial de Saúde (OMS), a Organização das Nações Unidas para a Alime...ntação e a Agricultura (FAO) e a Organização Mundial de Saúde Animal (OIE) e apresentados no Plano de Ação Global sobre Resistência aos Antimicrobianos. O objetivo geral dos planos de ação é garantir que se mantenha a capacidade de tratar e prevenir doenças infecciosas com medicamentos seguros e eficazes, que sejam de qualidade assegurada e que sejam utilizados de forma responsável e acessível a todos que deles necessitem.
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The goals and objectives of the Sudan National Action Plan on AMR can only be achieved through implementing strategic interventions and activities with all concerned ministries and departments joining hands with other stakeholders to collaboratively tackle these challenges.
This National Prevention Road Map addresses the above-mentioned challenges and aims to guide, focus and reinvigorate the HIV prevention response during the period 2018-2020. It also renews the commitment of political leadership,
2ª edição atualizada.
O Manual de Recomendações apresenta as diretrizes nacionais para o controle da doença, que incluem procedimentos clínicos padronizados, procedimentos laboratoriais, sistema de vigilância, ações de biossegurança e organização de serviços. Apesar de conter as reco...mendações clínicas no que diz respeito à padronização de ações de busca de casos e tratamento, o manual está destinado às ações voltadas para a saúde pública e não pretende ser um guia clínico sobre a doença. Dessa forma, não substitui livros, textos e publicações acadêmicas que identifiquem boas práticas clínicas sobre a abordagem do sintomático respiratório e do paciente com tuberculose nos seus variados aspectos e especificidades.
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In order to streamline and effectively control compounding of medicinal products in hospitals and pharmacies, these Guidelines for Production of Extemporaneous and Hospital Based Sterile Preparations has been crafted. The purpose of these guidelines therefore is to assist pharmacists in ...discharging their legal and professional obligations to patients in the area of extemporaneous dispensing. This guidance will help to assure the safe and appropriate preparation and supply of extemporaneously prepared medicinal products to patients, where
the supply of such products is necessary.
Extemporaneous and hospital based sterile preparations are critical for patients whose clinical needs cannot be met by registered medicinal products. The guidelines outline the principles and application of the concepts of Good Manufacturing Practice (GMP) requirements for premises, equipment, personnel, storage, quality management system, quality control, compounding processes as well as documentation.
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Antimicrobial resistance (AMR) has emerged as a major public health concern, around which the international leadership has come together to form strategic partnerships and action plans. The main driving force behind the emergence of AMR is selection pressure created due to consumption of antibiotics.... Consumption of antibiotics in human as well as animal sectors are driven by a complex interplay of determinants, many of which are typical to the local settings.
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