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Mental health and HIV/AIDS: the need for an integrated response

R. H. Remien; M. J. Stirratt; N. Nguyen; et al. AIDS; Wolters Kluwer (2019) CC

Editorial Review AIDS 2019, 33:1411–1420

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Antibiotic Prescribing in DR Congo: A Knowledge, Attitude and Practice Survey among Medical Doctors and Students

Thriemer K, Katuala Y, Batoko B, Alworonga J-P, Devlieger H, et al. PLoS ONE (2013) CC

Antibiotic resistance (ABR) particularly hits resource poor countries, and is fuelled by irrational antibiotic (AB) prescribing. We surveyed knowledge, attitudes and practices of AB prescribing among medical students and doctors in Kisangani, DR Congo.

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Mobile Populations

M. Smelyanskaya, J. Duncan (The Focus Group Consulting); C. Daniels, et al. Stop TB Partnership; UNOPS; END TB (2015) C1

Key populations brief.

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Early versus late BCG vaccination in HIV-1- exposed infants in Uganda: study protocol for a randomized controlled trial

V. Nankabirwa , J. K. Tumwine, O. Namugga, et al. Trials; BooMed Central (2017) CC

Trials (2017) 18:152, DOI 10.1186/s13063-017-1881-z

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HIV and young people who inject drugs

A. Armstrong; J. Baer; R. Baggaley; et al. UNAIDS; World Health Organization; UNFPA; et al. (2015) C_WHO

Technical Brief

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Take Charge! A Reproductive Health Guide for Women with Disabilities

Healy, K.; Panko Reis, J.; M. Martin Access Living; The Empowered Fe Fes (2016) CC

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Traumatic stress and psychological functioning in a South African adolescent community sample

Swain, K.D., Pillay, B.J. & Kliewer, W. South African Journal of Psychiatry (2017) CC

Background: Traumatic stress may arise from various incidents often leading to posttraumatic stress disorder (PTSD). The lifetime prevalence of PTSD is estimated at 1% – 2% in Western Europe, 6% – 9% in North America and at just over 10% in countries exposed to long-term violence. In South Afri... more

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Pathophysiology of the human immunodeficiency virus

N. R. Calles; D. Evans; D.L. Terlonge Baylor International Pediatric AIDS Initiative (BIPAI) (2019) C2

Accessed: 03.09.2019

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Anaesthesia equipment for resource-poor environments

B. A. McCormick and R. J. Eltringham (2007) CC

The design of anaesthesia equipment for use in hospitals in the developing world must take intoaccount the local conditions, particularly whether reliable supplies of compressed oxygen andelectricity are available. Designs should ensure that maintenance is feasible locally. Internationalstandards sh... more

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New Perspectives on Global Health Spending for Universal Health Coverag

Xu K., Soucat A., Kutzin J., et al. World Health Organization (2018) C_WHO

The report summarizes key global health expenditure patterns and trends, and illustrates the potential of the new database to inform thinking about financing reforms to progress towards UHC, and also raises issues for further research. It analyses the following areas:

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Methadone maintenance treatment and mortality in people with criminal convictions: A population-based retrospective cohort study from Canada

A. Russolillo; A. Moniruzzaman; J. M. Somers PLOS Medicine (2018) CC

Research Article PLOS Medicine | https://doi.org/10.1371/journal.pmed.1002625 July 31, 2018 / 1-19

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The global threat of Zika virus to pregnancy: epidemiology, clinical perspectives, mechanisms, and impact

Boeuf, P.; H.E. Drummer; J.S. Richards, et al. (2016) CC

BMC Medicine201614:112 DOI: 10.1186/s12916-016-0660-0

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HIV/AIDS prevention, care and treatment in the Region of the Americas: achievements, challenges and perspectives

F. Pérez; G. Ravasi; J. Peter Figueroa; et al. PAHO (Pan American Health Organization; World Health Organization); Iris (Institutional Repository); Rev Panam Salud Publica; Pan American Journal of Public Health (2016) C2

Overview Rev Panam Salud Publica 40(6), 2016

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Public perceptions of intellectual disability in a shantytown community in Lima, Peru

M.S. O’Shea, J. M.Girón, L. Cabrera, et al. (2012) CC

Int Health. 2012 December 1; 4(4): 253–259. doi:10.1016/j.inhe.2012.07.001

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Transmission modelling of environmentally persistent zoonotic diseases: a systematic review

Rees, E.M.; A. Minter, J. Edmunds et al. The Lancet (2021) CC

The Lancet Planetary Health Volume 5, ISSUE 7, e466-e478, July 01, 2021 Transmission of many infectious diseases depends on interactions between humans, animals, and the environment. Incorporating these complex processes in transmission dynamic models can help inform policy and disease control int... more

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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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Investigation of the Quality of the 12 Most-Used Antibiotics Available in Retail Private Pharmacies in Rwanda

Bizimana, T.; Kagisha, V.; Nyandwi, J.B: et al. MDPI Antibiotics (2022) CC

Antibiotics 2022, 11(3), 329; https://doi.org/10.3390/antibiotics11030329. The authors found that the most-represented antibiotics on the Rwandan market were amoxicillin, co-trimoxazole and cloxacillin. No counterfeit antibiotics were found in this study. However, substandard batches with moderate ... more

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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC

This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more

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Financing HIV Programming: How Much Should Low And Middle-Income Countries and their Donors Pay?

Galarraga, O.; V. J. Wirtz; Y. Santa-Ana-Tellez et al. PLOS One (2013) C1

Global HIV control funding falls short of need. To maximize health outcomes, it is critical that national governments sustain reasonable commitments, and that international donor assistance be distributed according to country needs and funding gaps. We develop a country classification framework in t... more

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Infrastructure, policy and regulatory interventions to increase physical activity to prevent cardiovascular diseases and diabetes: a systematic review

Durão, S.; Burns, J.; Schmidt, B. et al. BMC Public Health (2023) CC

Background Noncommunicable diseases are major contributors to morbidity and mortality worldwide. Modifying the risk factors for these conditions, such as physical inactivity, is thus essential. Addressing the context or circumstances in which physical activity occurs may promote physical activity a...t a population level. We assessed the effects of infrastructure, policy or regulatory interventions for increasing physical activity. Methods We searched PubMed, Embase and clinicaltrials.gov to identify randomised controlled trials (RCTs), controlled before-after (CBAs) studies, and interrupted time series (ITS) studies assessing population-level infrastructure or policy and regulatory interventions to increase physical activity. We were interested in the effects of these interventions on physical activity, body weight and related measures, blood pressure, and CVD and type 2 diabetes morbidity and mortality, and on other secondary outcomes. Screening and data extraction was done in duplicate, with risk of bias was using an adapted Cochrane risk of bias tool. Due to high levels of heterogeneity, we synthesised the evidence based on effect direction. Results We included 33 studies, mostly conducted in high-income countries. Of these, 13 assessed infrastructure changes to green or other spaces to promote physical activity and 18 infrastructure changes to promote active transport. The effects of identified interventions on physical activity, body weight and blood pressure varied across studies (very low certainty evidence); thus, we remain very uncertain about the effects of these interventions. Two studies assessed the effects of policy and regulatory interventions; one provided free access to physical activity facilities and showed that it may have beneficial effects on physical activity (low certainty evidence). The other provided free bus travel for youth, with intervention effects varying across studies (very low certainty evidence). Conclusions Evidence from 33 studies assessing infrastructure, policy and regulatory interventions for increasing physical activity showed varying results. The certainty of the evidence was mostly very low, due to study designs included and inconsistent findings between studies. Despite this drawback, the evidence indicates that providing access to physical activity facilities may be beneficial; however this finding is based on only one study. Implementation of these interventions requires full consideration of contextual factors, especially in low resource settings. more