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Diagnostics to support the eradication of yaws—Development of two target product profiles

Fongwen, N.; Handley, B.; Martin, D. et al. PLoS Neglected Tropical diseases (2022) CC
Yaws is targeted for eradication by 2030, using a strategy based on mass drug administration (MDA) with azithromycin. New diagnostics are needed to aid eradication. Serology is currently the mainstay for yaws diagnosis; however, inaccuracies associated with current serological tests makes it difficu... more
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Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in the Americas

Braae, U.; Thomas, L.; Roberson, L. et al. Parasites and Vectors (2018) CC
Taenia saginata is a zoonotic tapeworm that is of economic importance in countries where cattle are kept. The parasite is transmitted from human tapeworm carriers (taeniosis) to bovines (cysticercosis) by excretion of eggs or proglottids containing eggs into the environment via the stool. Bovines ca... more
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Laboratory techniques in rabies

Rupprecht, C.; Fooks, A,; Abela-Ridder, B. World Health Organization WHO (2018) C_WHO
Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory-based surveillance, production of biologicals ... more
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Philippine Action Plan to Combat AMR: One Health Approach

Phillipine Department of Health (2019) C_WHO
Antibiotics have been useful in fighting infectious diseases in our country for decades, but because of the overuse and misuse of these agents, an increasing number of organisms are now resistant to them. The Philippines, like other Southeast Asian countries, has already been encountering the many c... more
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USA National Action Plan for Combating Antibiotic Resistant Bacteria 2020-2025

U.S. Government (2020) C2
The National Action Plan for Combating Antibiotic-Resistant Bacteria (CARB), 2020-2025, presents coordinated, strategic actions that the United States Government will take in the next five years to improve the health and wellbeing of all Americans by changing the course of antibiotic resistance. T... more
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Antibiotic stewardship interventions in hospitals in low-and middle-income countries: a systematic review

Van Dijck C., Vlieghe E., Cox J.A. Bulletin of the World Health Organization (2018) C_WHO
Objective: To review the effectiveness of antibiotic stewardship interventions in hospitals in low- and middle-income countries.
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Worldwide Control and Management of Chagas Disease in a New Era of Globalization: a Close Look at Congenital Trypanosoma cruzi Infection.

Abras A., Ballart C., Fernández-Arévalo A., et al. Clinical Microbiology Reviews (2022) CC
Population movements have turned Chagas disease (CD) into a global public health problem. Despite the successful implementation of subregional initiatives to control vectorial and transfusional Trypanosoma cruzi transmission in Latin American settings where the disease is endemic, congenital CD (cCD... more
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Drugs to prevent COVID-19: living guideline

World Health Organisation (WHO) (2023) C_WHO
The WHO Living guideline: Drugs to prevent COVID-19 contains the Organization’s most up-to-date recommendations for the use of drugs to prevent COVID-19. The latest version of this living guideline is available in pdf format (via the ‘Download’ button) and via an online platform. Guidelines ... more
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Abordar la violencia contra las mujeres en las políticas y los protocolos de salud de la Región de las Américas. Un informe de la situación regional

World Health Organisation (WHO) (2023) C_WHO
La violencia contra las mujeres y las niñas es generalizada en la Región de las Américas, y tiene enormes consecuencias para su salud y bienestar, así como el de sus familias y sus comunidades. Se trata de un costo inaceptable que puede ser prevenido mediante acciones basadas en la evidencia, pr... more
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Addressing violence against women in health policies and protocols in the Americas: A regional status report

World Health Organisation (WHO) (2023) C_WHO
Violence against women and girls is widespread in the Region of the Americas, resulting in enormous consequences for the health and wellbeing of women and girls, their families and communities. These costs are unacceptable and they can be prevented through evidence-based action, including the health... more
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Praziquantel for the treatment of schistosomiasis during human pregnancy

Friedman, J.F. et al. (2018) CC
In 2014, an estimated 40 million women of reproductive age were infected with Schistosoma haematobium, S. japonicum and/or S. mansoni. In both 2003 and 2006, the World Health Organization (WHO) recommended that all schistosome-infected pregnant and breastfeeding women be offered treatment, with praz... more
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EU Guidelines for the prudent use of antimicrobials in human health

European Centre for Disease Prevention and Control (ECDC) (2017) C_CDC
These Guidelines on prudent use of antimicrobials in human health are based on a technical report prepared by the European Centre for Disease Prevention and Control (ECDC) with input from EU Member States experts and stakeholders, which should be referred to for details of the methodology used in cr... more
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Clinical utlity of peptide microarrys in the serodiagnosis of neglected tropical diseases in sub-Saharan Africa: protocol for a diagnostic test accuracy sytematic review

Vengesai A., Naicker T., Kasambala M., et al. BMJ Open (2021) C2
Neglected tropical diseases tend to cluster in the same poor populations, and to make progress with their control, they will have to be dealt with in an integrated manner. Peptide microarrays may be a solution to tese problems, where diagnosis for co-infection can be detected simultaneously using th... more
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Mission Rabies Annual Report 2018

Mission Rabies (2018) CC
2018 has been one of the most successful years ever for Mission Rabies. We are on the cusp of having almost vaccinated one million dogs in global rabies hotspots, we’ve educated over two million children and we’re seeing a dramatic reduction in both human and canine rabies in all our flagship... more
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WHO Guide for Rabies Pre and Post Exposure Prophylaxis in Humans

World Health Organization WHO (2014) C_WHO
WHO strongly recommends discontinuation of the nerve tissue vaccine, and replacement with modern concentrated and purified cell culture derived vaccines (CCDV) and embryonated eggbased rabies vaccines. These vaccines must comply with WHO criteria for potency and innocuity following satisfactory ass... more
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Implementation plan and monitoring and evaluation framework of the WHO European framework for action to achieve the highest attainable standard of health for persons with disabilities 2022–2030

World Health Organisation (WHO) (2022) C_WHO
This background document (‎EUR/RC72/BG/7)‎ was considered and adopted by the WHO Regional Committee for Europe at its 72nd session (‎Tel Aviv, Israel, 12–14 September 2022)‎, together with the working document (‎EUR/RC72/7)‎ and information document (‎EUR/RC72/INF./4)‎. The Regiona... more
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Clinical management of COVID-19: living guideline, 13 January 2023

World Health Organisation (WHO) (2023) C_WHO
As of 12 December 2022, over 645 million people worldwide have been diagnosed with COVID-19, with over 6.6 million deaths (4). The Omicron variant, which emerged in late November 2021, and its subvariants, are now the dominant circulating viruses, contributing to the ongoing surge in several countr... more
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Technical handbook for dengue surveillance, dengue outbreak prediction/detection and outbreak response (“model contingency plan”)

World Health Organization WHO; TDR Program (2017) C_WHO
The aim of this “model contingency plan” is to assist programme managers and planners in devel-oping a national, context-specific, dengue outbreak response plan in order to: (a) detect a dengue outbreak at an early stage through clearly defined and validated alarm signals; (b) precisely define w... more
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Mali national action plan on antimicrobial resistance: review of progress in the human health sector

World Health Organisation (WHO) (2023) C_WHO
This policy brief aims to provide a review of the current progress on implementing the Mali national action plan on AMR, identifies critical gaps, and highlights findings to accelerate further progress in the human health sector. The target audience includes all those concerned with implementing act... more
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Elimination of onchocerciasis in Africa by 2025: the need for a broad perspective

Cupp, E.; Sauerbrey, M.; Cama, V. et al. National Library of Medicine (2019) CC
In response to the recent publication “Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes” by Dadzie et al., it is important to clarify and highlight the positive and unequivocal research and operational contributio... more