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World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions

The WHO CVD Risk Chart Working Group The Lancet Global Health (2019) CC

To help adapt cardiovascular disease risk prediction approaches to low-income and middle-income countries, WHO has convened an effort to develop, evaluate, and illustrate revised risk models. Here, we report the derivation, validation, and illustration of the revised WHO cardiovascular disease risk ... more

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Policy Snapshot: Cholesterol Control and Management in Brazil

World Heart Federation (2015) CC

Worldwide, there are about 17 million deaths due to cardiovascular disease (CVD) each year and at least two or three times as many non-fatal events. Raised cholesterol greatly increases the risks of stroke and heart disease, causing a large health burden across the world. The World Health Organizat... more

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Primary and Secondary Prevention of Ischemic Stroke

Paciaroni, M.; Bogousslavsky, J. European Neurology (2010) CC

Prevention of stroke and transient ischemic attack includes both conventional approaches to vascular risk factor management (blood pressure lowering, cholesterol reduction with statins, smoking cessation and antiplatelet therapy) and more specific interventions, such as carotid revascularization or... more

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Trend analysis of cardiovascular disease mortality, incidence, and mortality-to-incidence ratio: results from global burden of disease study 2017

Amini, M.; Zayeri, F.; Salehi, M. BioMed Central (2021) CC

Background Cardiovascular diseases (CVDs) are one of the global leading causes of concern due to the rising prevalence and consequence of mortality and disability with a heavy economic burden. The objective of the current study was to analyze the trend in CVD incidence, mortality, and mortality-to-... more

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Limited access to CVD medicines in low-income and middle-income countries: poverty is at the heart of the matter

Agyemang, C.; van den Born, B. The Lancet Global Health (2018) CC

Non-communicable diseases (NCDs) pose a substantial threat to many health systems, especially in low-income and middle-income countries (LMICs) where they are already overstretched. In the past few decades, deaths from NCDs in LMICs have spiked, whereas numbers in high-income countries have stabilis... more

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Cancer Education Materials

Global Oncology (2024) C2

Website last accessed on 16.03.2024 GO developed our Cancer Education Materials (CEM) tool to improve the patient diagnosis and treatment experience in resource-limited settings, reduce stigma, help facilitate dialogue between patients and providers, and ensure that no patient stops treatment beca... more

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Cancer: Disease Control Priorities, Third Edition (Volume 3)

Gelband H., Jha P., Sankaranarayanan R. et al. International Bank for Reconstruction and Development The World Bank (2015) C2

Volume 3, Cancer, presents the complex patterns of cancer incidence and death around the world and evidence on effective and cost-effective ways to control cancers. The DCP3 evaluation of cancer will indicate where cancer treatment is ineffective and wasteful, and offer alternative cancer care packa... more

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CANSA's Position Statements & Fact Sheets

CANSA - The Cancer Association of South Africa (2024) C2

Website last accessed on 16.03.2024 : CANSA’s Fact Sheets & Position Statements are provided for general information purposes only, and to state our stance on particular matters. We do not specialise in treatment of cancer. It is therefore important to discuss any questions which may arise with th... more

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Capacity building for cancer prevention and early detection in the Ugandan primary healthcare facilities: Working toward reducing the unmet needs of cancer control services

Jatho A., Mugisha N.M., Kafeero J. et al Cancer Medicine (2020) C2

In 2018, approximately 60,000 Ugandans were estimated to be suffering from cancer. It was also reported that only 5% of cancer patients access cancer care and 77% present with late-stage cancer coupled with low level of cancer health literacy in the population despite a wide coverage of primary heal... more

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The state of diabetes treatment coverage in 55 low-income and middle-income countries: a cross-sectional study of nationally representative, individual-level data in 680 102 adults

Flood, D.; Seiglie, J.A.; Dunn, M.; et al. The Lancet healthy Longevity (2021) C2

Approximately 80% of the 463 million adults worldwide with diabetes live in low-income and middle-income countries (LMICs). A major obstacle to designing evidence-based policies to improve diabetes outcomes in LMICs is the scarce availability of nationally representative data on the current patterns... more

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Individual-level data in 680 102 adults, The state of diabetes treatment coverage in 55 low-income and middle-income countries: a cross-sectional study of nationally representative

Flood, D.; Seiglie, J.A.; Dunn, M.; et al. The Lancet healthy Longevity (2021) C2

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Management of Type 2 Diabetes in Developing Countries: Balancing Optimal Glycaemic Control and Outcomes with Affordability and Accessibility to Treatment

Mohan, V.; Khunti, K.; Chan,S.P.; et al. National Library of Medicine, National Center for Biotechnology Information (2020) CC3

With the growing prevalence of type 2 diabetes, particularly in emerging countries, its management in the context of available resources should be considered. International guidelines, while comprehensive and scientifically valid, may not be appropriate for regions such as Asia, Latin America or Afr... more

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Epidemiology of type 2 diabetes in India

Pradeepa, R.; Mohan, V. Indian Journal of Ophthalmology 69(11):p 2932-2938, November 2021. (2021) CC2

The burden of diabetes is high and increasing globally, and in developing economies like India, mainly fueled by the increasing prevalence of overweight/obesity and unhealthy lifestyles. The estimates in 2019 showed that 77 million individuals had diabetes in India, which is expected to rise to over... more

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Diabetes Mellitus: Insights from Epidemiology, Biochemistry, Risk Factors, Diagnosis, Complications and Comprehensive Management

Alam, S.; Hasan, K.; Neaz, S.; et al. Molecular Diversity Preservation International MDPI (2021) CC2

Diabetes mellitus has become a serious and chronic metabolic disorder that results from a complex interaction of genetic and environmental factors, principally characterized by hyperglycemia, polyuria, and polyphagia. Uncontrolled high blood sugar can result in a host of diabetic complications. Prol... more

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Guidelines for the prevention, diagnosis, care and treatment for people with chronic hepatitis B infection (March 2024)

World Health Organization WHO (2024) C_WHO

Hepatitis B (HBV) infection is a major public health problem and cause of chronic liver disease. The 2024 HBV guidelines provide updated evidence-informed recommendations on key priority topics. These include expanded and simplified treatment criteria for adults but now also for adolescents; expa... more

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Type 1 diabetes estimates in children and adults

International Diabetes Federation (2021) CC2

Given that only 1.52 million of the 8.75 million people living with type 1 diabetes around the world in 2022 were less than 20 years old, the lack of data available for adult populations presents a stark gap in the research. Without rapid diagnosis and appropriate treatment, type 1 diabetes leads to... more

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Pharmacological Primary Prevention of Diabetes Mellitus Type II: A Narrative Review

Naveed, A.; Farrukh, L.; Khawar Sana, M.; et al. National Library of Medicine (2020) CC2

The evolving epidemic of type 2 diabetes mellitus has challenged health-care professionals. It stands among the leading causes of mortality in the present world. It warrants new and versatile approaches to improve mortality and the associated huge quality-adjusted life years lost to it once diagnose... more

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Prioritization of treatments for lower extremity peripheral artery disease in low- and middle-income countries

Fowkes, G.F.; Forster, R.B.; Levin, C.E. et al. International Angiology (2017) CC3

INTRODUCTION: Lower extremity peripheral artery disease (PAD) is increasing in prevalence in low- and middle-income countries creating a large health care burden. Clinical management may require substantial resources but little consideration has been given to which treatments are appropriate for les... more

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Prevention, Screening and Control of Common Non-Communicable Diseases: Hypertension, Diabetes an Common Cancers (Oral, Breast, Cervix)

National Health Mission (2016) CC

Comprehensive Primary Health Care has an important role in the primary and secondary prevention of several disease conditions, including non-communicable diseases which today contribute to over 60% of the mortality in India. The provision of Comprehensive primary health care reduces morbidity, disab... more