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Publication Years
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A Clinical Guideline for the Diagnosis and Treatment of Drug-susceptible TB in Children and Adolescents in South Africa. This new guidance is aligned with the updated WHO guidelines but has been adapted specifically for the South African context. The intention of this publication is to provide g ... more
This document aims to provide Ministry of Health guidance on the implementation of PEP and PrEP to prevent HIV transmission and improve overall health outcomes. This comprehensive approach reflects the commitment of all involved in combating HIV and enhancing public health.
This technical brief describes promising models that demonstrate how FBOs could contribute to expanded access to improved HIV and other services for men. These models incorporate a range of WHO-recommended interventions and highlights operational considerations and key success factors. By capitalizi ... more
Final Policy
Advanced Clinical Care (ACC) Live Tutorial session 22 August 2024
The paper “Artificial Intelligence for Public Health Surveillance in Africa: Applications and Opportunities” examines how artificial intelligence (AI) can improve public health systems across Africa, particularly in low-resource settings. It explores how machine learning and other AI techniques ... more
This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu ... more

The Health Emergency and Disaster Risk Management

Chan E.Y.Y., Huang Z., Hung K.K.C. et al United Nations Office for Disaster Risk Reduction UNDRR (2022) CC
An emerging framework for achieving synergies among the Sendai Framework, the 2030 Agenda for Sustainable Development, the New Urban Agenda and the Paris Agreement. This paper discusses the potential of the Health Emergency and Disaster Risk Management (Health-EDRM) Framework in promoting syne ... more
Why we need Targets for 2025. 1.2020 Fast Track targets will soon elapse; 2. Current UNAIDS strategy concludes in 2021; 3. Informs possible UN General Assembly Special Session on AIDS in 2021; where a new Political Declaration on AIDS would be adopted; 4. Informs the strategies of other organisatio ... more
Female genital mutilation (FGM) is a human rights violation deeply rooted in gender inequality and discrimination. FGM violates various human rights under international human rights law including, among others, the rights to equality, life and health and the rights to be free from discrimination, to ... more
International Journal for Parasitology: Drugs and Drug Resistance Volume 28, August 2025, 100602 This review provides innovative insights to circumvent antimalarial drug resistance and diversify malaria therapeutics.
This issue brief aims to provide a comprehensive overview of key publications, guidelines, and practical materials on malaria prevention, diagnosis, and treatment. The selected documents reflect current evidence and field-based experiences, supporting healthcare professionals, researchers, and publ ... more
This guidance addresses one type of generative AI, large multi-modal models (LMMs), which can accept one or more type of data input and generate diverse outputs that are not limited to the type of data fed into the algorithm. It has been predicted that LMMs will have wide use and application in heal ... more
A process for improving community awareness and preparedness for technological hazards and environmental emergencies
These guidelines provide a recommendation on iodine thyroid blocking (ITB), via oral administration of stable iodine, as an urgent protective action in responding to a nuclear accident. This recommendation aims to support emergency planners, policy makers, public health specialists, clinicians and o ... more
Lack of satisfactory progress in mainstreaming disaster risk reduction within development is attributed to various factors. One of the important factor that is often not much appreciated is the inadequate comprehension of mainstreaming and the absence of clear, cogent and practical guidelines, tools ... more
In disaster preparedness, the participation of women, children, older people, persons with disabilities (PWDs), and other minority groups and sectors is important because they are the most vulnerable against disasters. Inclusive disaster preparedness provides technical and logical frameworks that as ... more
A Step-by-Step, Research-Informed and Faith-Based Planning Manual