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https://doi.org/10.1016/j.vaccine.2019.09.099
The article "Economic burden of cholera in Asia" examines the financial impact of cholera in 14 Asian countries. It analyzes costs related to treatment, out-of-pocket expenses,
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and lost productivity due to illness and premature deaths. The study estimates that cholera caused approximately $41 million in direct costs and $946 million in lost productivity in 2015. It highlights the significant economic burden on public health systems and households, emphasizing the need for investments in cholera prevention, including improved sanitation, clean water access, and vaccination programs.
more
The Manual for Indoor Residual Spraying in Urban Areas for Aedes aegypti Control is intended not only for operational personnel and middle and senior mana
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gement of programs responsible for the prevention and control of Aedes-borne diseases, but also for the academic community involved in Aedes research, private pest control personnel, and the general public.
more
Workplace Pandemic Preparedness. Facilitator Training Manual
Ministry of Health Ghana; NADMO Ghana
GiZ Deutsche Gesellschaft für Internationale Zusammenarbeit
(2013)
C1
The Facilitator Training Manual on Workplace Pandemic Preparedness is a guide developed by GIZ and the Ministry of Health to help organizations prepare for and respond to pandemics while ensuring bu
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siness continuity. It provides structured guidance on training, risk assessment, prevention, and response strategies for both medical and non-medical personnel.
Key topics include pandemic preparedness and response, covering diseases like Influenza, Cholera, Yellow Fever, and Meningitis, as well as personal hygiene, risk communication, and business continuity planning. The manual emphasizes participatory learning, practical training, and leadership in crisis management, aiming to enhance institutional resilience and ensure workplaces remain safe and operational during health crises.
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Heart failure with a reduced ejection fraction (HFrEF) is a condition frequently encountered by healthcare professionals and, in order to achieve the best outcomes for patients, needs to be managed optimally. This guideline document is based on the
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European Society of Cardiology Guidelines for the treatment of acute and chronic heart failure published in 2016, and summarises what is considered the best current management of patients with the condition. It provides information on the definition, diagnosis and epidemiology of HFrEF in the African context. The best evidence-based treatments for HFrEF are discussed, including established therapies (beta-blockers, ACE-i/ARBs, mineralocorticoid receptor antagonists (MRAs), diuretics) that form the cornerstone of heart failure management as well as therapies that have only recently entered clinical use (angiotensin receptor-neprilysin inhibitor (ARNI), sodium/glucose cotransporter-2 (SGLT2) inhibitors). Guidance is offered in terms of more invasive therapies (revascularisation, implantable cardioverter defibrillators (ICDs) and cardiac resynchronisation therapy (CRT) by implantation of a biventricular pacemaker with (CRT-D) or without (CRT-P) an ICD, left ventricular assist device (LVAD) use and heart transplantation) in order to ensure efficient use of these expensive treatment modalities in a resourcelimited environment. Furthermore, additional therapies (digoxin, hydralazine and nitrates, ivabradine, iron supplementation) are discussed and advice is provided on general preventive strategies (vaccinations). Sections to discuss conditions that are particularly prevalent in sub-Saharan Africa (HIV-associated cardiomyopathy (CMO), peripartum CMO, rheumatic heart disease, atrial fibrillation) have been added to further improve clinical care for these commonly encountered disease processes.
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The WHO Guide on Cholera Control in Complex Emergencies provides key steps for preparedness, prevention, and response to cholera and other diarrhea
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l diseases in crisis situations. It highlights the importance of early warning systems, rapid response, and coordination among health agencies. The guide outlines measures for case management, water sanitation, hygiene promotion, and outbreak containment, particularly in refugee camps and disaster-affected areas. It emphasizes community involvement, surveillance, and proper health infrastructure to reduce mortality and control disease spread in vulnerable populations.
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WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention
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approaches.
HIV drug resistance has been rarely reported among PrEP users who tested HIV positive in randomized controlled trials or open-label studies. However, PrEP-selected HIV drug resistance could potentially negatively impact the effectiveness of treatment options among PrEP users who acquire HIV, since there is a potential for overlapping resistance profiles between antiretroviral drugs used for both PrEP and first-line antiretroviral therapy.
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Aider les mères à survivre. Saignement Après la Naissance. GUIDE DU PRESTATAIRE
Jhpiego; UNFPA; International Confideration of Midwives; et al.
Jhpiego; UNFPA; International Confideration of Midwives
(2013)
This guide supports the low-dose, high-frequency practice of scenerios needed to maintain competency in prevention and management of postpartum hem
...
orrhage. The document is learner centered and is directly linked to service delivery standards. It is part of the Helping Mothers Survive Bleeding After Birth training package.
more
Como Ajudar as Mães a Sobreviverem. Hemorragia Pós-parto. Manual do Provedor
Jhpiego; UNFPA; International Confideration of Midwives; et al.
Jhpiego; UNFPA; International Confideration of Midwives
(2013)
This guide supports the low-dose, high-frequency practice of scenerios needed to maintain competency in prevention and management of postpartum hem
...
orrhage. The document is learner centered and is directly linked to service delivery standards. It is part of the Helping Mothers Survive Bleeding After Birth training package.
more
Kuwasaidia Wamama Wazazi kuishi. Utokwaji damu baada ya kujifungua. Mwongozo kwa watoa Huduma
Jhpiego; UNFPA; International Confideration of Midwives; et al.
Jhpiego; UNFPA; International Confideration of Midwives
(2013)
This guide supports the low-dose, high-frequency practice of scenerios needed to maintain competency in prevention and management of postpartum hem
...
orrhage. The document is learner centered and is directly linked to service delivery standards. It is part of the Helping Mothers Survive Bleeding After Birth training package.
more
Helping Mothers Survive. Bleeding after Birth. Provider's Guide (English with South Asia graphics)
Jhpiego; UNFPA; International Confideration of Midwives; et al.
Jhpiego; UNFPA; International Confideration of Midwives; et al.
(2013)
C1
This guide supports the low-dose, high-frequency practice of scenerios needed to maintain competency in prevention and management of postpartum hem
...
orrhage. The document is learner centered and is directly linked to service delivery standards. It is part of the Helping Mothers Survive Bleeding After Birth training package.
more
The study on health facility preparedness for cholera outbreak response in Cameroon evaluates the ability of healthcare facilities in four cholera-prone districts to manage cholera outbreaks. The findings highlight significant weaknesses, including limited surveillance systems, inadequate access to
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water, poor sanitation, and lack of essential medical supplies such as Oral Rehydration Solution (ORS) and cholera case management guidelines. Many health facilities also lacked trained personnel and proper waste disposal systems, increasing the risk of disease spread within healthcare centers. The study underscores the urgent need for improved hygiene infrastructure, better training, and resource allocation to enhance outbreak response and reduce cholera-related mortality.
more
Research to develop point-of-care tests is in progress. Treatment of Buruli ulcer comprises 8 weeks of combined antibiotics (rifampicin and clarithromycin). Complementary therapies such as wound car
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e, skin graft and prevention of disability are needed in some cases to ensure full recovery.
The target set by the World Health Organization (WHO) for control of Buruli ulcer is for countries to achieve a rate of case confirmation by PCR of at least 70%. All endemic countries have at least one PCR facility to support confirmation of cases. However, most countries in the WHO African Region have not been able to reach the target, and the rate of case confirmation has been declining
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An integrated approach is particularly important for low-resource settings for efficient use of limited resources. The course contents will include risk factors, clinical course, guidance and protocols for diagnosis,
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management and referral as needed for NCDs in PHC. SEARO NCD PEN-HEARTS is a series of four courses with the other three courses focusing on Hearts of NCD: an integrated approach to management of NCDs in PHC, diabetic foot care and palliative care that will enable the learner to plan and deliver NCD services.
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International Society of Paediatric Surgical Oncology (IPSO) Surgical Practice Guidelines
recommended
ecancer has just published a comprehensive set of guidelines for paediatric cancer surgery, applicable to low and high resource settings across the world. You can read the guidelines online
The guidelines have been developed by the International
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Society of Paediatric Surgical Oncology (IPSO) with authors from both High Income Countries and Lower and Middle Income Countries, and have been further validated by experts in the respective fields with the aim of providing evidence-based information for surgeons who care for children with cancer.
These guidelines include information on the care and treatment of children with malignancies, including making a diagnosis, obtaining adequate venous access, performing a surgical resection for solid tumours (with staging and reconstruction), performing procedures for cancer prevention and its late effects, and managing complications of treatment; all with the goal of improving survival and quality of life.
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In 2009, WHO’s Second International Conference on Buruli Ulcer Control and Research resolved to strengthen the capacity of national laboratories to confirm cases of the disease, but advised that “efforts are still needed to develop simple diagno
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stic tools usable in the field as well as disability prevention methods”.
In 2013, WHO and the Foundation for Innovative New Diagnostics convened a meeting of Buruli ulcer experts in Geneva, Switzerland (9) at which two priority unmet needs in diagnosis were identified:
a diagnostic test for early detection of Buruli ulcer in symptomatic patients with sufficient positive predictive value to put patients on appropriate treatment; and
a screening test at the primary health care or community level for symptomatic patients with ulcer
more
Glaucoma is a leading cause of irreversible blindness globally. In Malawi, glaucoma accounts for 15.8% of the blindness among people aged 50 years and above. Blindness from glaucoma is preventable with early detection
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and timely treatment. However, glaucoma management remains a challenge to eye care providers due to its asymptomatic progression.
These guidelines inform eye care providers about the requirements for early detection of glaucoma, and the appropriate assessment and management of glaucoma patients. The guidelines also demonstrate the need for ophthalmologists to work with secondary-level eye care providers. With
glaucoma being a permanently blinding condition, it is vital to ensure that all eye care providers are adequately equipped with skills and resources for the early detection and management of glaucoma.
more
This is a detailed manual giving a step by step approach to undertaking the pharmacovigilance of antiretrovirals. It is intended to be a source of practical advice for Pharmacovigilance Centres and health professionals involved in HIV/AIDS
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prevention and treatment programmes. A number of WHO publications are available that provide a background to pharmacovigilance and, as far as possible, that material will not be repeated here. Health officials, planners, the staff of Pharmacovigilance Centres, public health teams and all health workers should become familiar with these publications, which are: • Safety of Medicines: A guide to detecting and reporting adverse drug reactions
more
Global Action Plan on Antimicrobial Resistance
recommended
The goal of the draft global action plan is to ensure, for as long as possible, continuity of successful treatment and prevention of infectious dis
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eases with effective and safe medicines that are quality-assured, used in a responsible way, and accessible to all who need them.
more
The Mediclinic article on silicosis provides an overview of this occupational lung disease caused by inhaling silica dust. It explains that inhaled silica particles lead to lung scarring and nodule formation, progressively impairing breathing. The a
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rticle outlines symptoms such as shortness of breath, severe cough, fatigue, loss of appetite, chest pains, and fever. Diagnosis involves a medical examination, detailed occupational history, lung function tests, and imaging like chest X-rays or CT scans to detect lung scarring and nodules. While silicosis is irreversible with no specific cure, management focuses on preventing further silica exposure and treating complications. Preventive measures include maintaining high occupational health standards to control silica dust exposure.
more
The article from the European Respiratory Journal discusses the natural history of chronic obstructive pulmonary disease (COPD), emphasizing its increasing global impact on morbidity and mortality. It highlights that while cigarette smoking is a pri
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mary risk factor, other influences such as environmental exposures and genetics also play significant roles. The article notes that lung function, measured by FEV1 (forced expiratory volume in one second), is a critical indicator of both diagnosis and prognosis. It further explores the impact of exacerbations, comorbidities, and systemic inflammation on disease progression and outcomes. The need for comprehensive patient management, which considers various comorbid conditions and inflammatory factors, is emphasized to improve clinical outcomes and reduce healthcare costs.
more
