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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Update on COVID-19 vaccination in Syria

World Health Organization WHO; Eastern Mediterranean Region (2021) C_WHO

22 April 2021

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International Guidelines Human Rights and drug policy

M. Stoffregen UNAIDS; World Health Organization; UNDP; et al. (2019) C2

Accessed: 07.11.2019

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Preparing for and responding to global health emergencies

Cochrane Convenes (2022) C1

Learnings from the COVID-19 evidence response and recommendations for the future. Reflections and recommendations from the evidence synthesis community.

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Analysing the response of a Teacher Training Institution to HIV and AIDS: A case study from Zambia

Lucinda Ramos UNESCO (2007) CC

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Disability and Education. Summary of Results

Jacob R.S. Malungo, D. Nabuzoka, R. Paul, et al. UNICEF; Ministry of Community Development and Social Services Zambia, et al. (2018)

Qualitative study from Zambia on barriers to and facilitators of life-long learning

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Maintaining and prioritizing HIV prevention services in the time of COVID-19

UNAIDS; GPC (2020) CC

In the time of coronavirus disease (COVID-19), sex and drug use will continue, regardless of physical distancing orders and policies. People who previously met in community gathering venues such as bars and clubs may now meet in different sites, ones that are “hidden” or less accessible. This, i... more

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Syrian Public Health after COVID-19: Entry Points and Lessons Learned from the Pan

Center for Operational Analysis and Research COAR (2021) CC

March 2021

External Link

Pandemic influenza preparedness and response WHO guidance document

World Health Organization (2009)

This document should be used in conjunction with the WHO checklist for influenza preparedness planning published by the World Health Organization in 2005. Available in English; Chinese; French

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Iraq: Coronavirus Disease 2021 (COVID-19) - Weekly Situation Report (Week 31) (2 – 8 Aug 2021)

Office for the Coordination of Humanitarian Affairs OCHA (2021) C2

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Health and Socio-Economic Impacts of Physical Distancing for Covid-19 in Africa

Barasa, E.; et al. KEMRI-Wellcome Trust Research Programme and African Academy of Sciences (2020) CC

Physical distancing measures are important to reduce COVID-19 transmission. However, when stringently applied, they can result in negative health and socio-economic impacts. This report draws on a rapid review of available literature, case studies from across Africa and expert knowledge to make reco... more

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Menstrual Hygiene Management
recommended

Save the Children (2018) C2

Operational Guidelines. Guidelines for the development of educational programmes for MHM, including tips on the topics to address and methods to assess girls’ practices in a respectful way with practical tools

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Finding the Balance: Public Health and Social Measures in Cameroon

Partnership for Evidence-Based Response to COVID-19 (PERC) (2021) CC

This report describes findings from a telephone survey with 1,323 people conducted in February 2021. The survey examined how people respond to public health and social measures (PHSMs) to prevent COVID-19. The sample is representative of households with access to a landline or cell phone, but does n... more

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Responding to COVID-19 in Africa: Finding the Balance: Vaccine Confidence

Partnership for Evidence-Based Response to COVID-19 (PERC) African Union; Africa CDC Centres for Disease Control and Prevention; Ipsos; et al. (2021) CC

Key findings from a February 2021 survey from the Partnership for Evidence-Based Response to COVID-19 (PERC)

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Ukraine - Humanitarian Response Plan 2022 (February 2022)

Office for the Coordination of Humanitarian Affairs OCHA (2022) C1

Almost eight years of active fighting have had profound consequences on the lives of millions of people in the conflict-affected Donetska and Luhanska oblasts of eastern Ukraine. An estimated 2.9 million people are projected to need humanitarian assistance in 2022, with some 55 per cent living in th... more

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Global Advisory Committee on Vaccine Safety, 5–6 June 2019

World Health Organization WHO (2019) C_WHO

The Committee examined the clinical development of Ebola virus vaccines and conducted an inventory of available data on their safety. It also reviewed 3 generic issues: updating a global strategy on vaccine safety, use of a network of distributed data ... more

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Disaster Recovery Guidance Series - Communication during Disaster Recovery

World Bank, GFDRR (2019) C1

This Guide provides practical guidance for governments regarding how to effectively communicate with communities during the recovery phase following an emergency. It explains how to identify communication needs, and presents “best fit” communication methods and strategies to deploy to support Di... more

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WHO Information Series on School Health

World Health Organization (WHO); Unicef; Education International ; et al. World Health Organization (WHO); Unicef; Education International ; et al. (2004) C_WHO

Teachers' Exercise Book for HIV Prevention Document 6.1 This booklet contains all the participatory learning experiences that are included in the Training and Resource Manual on School Health and HIV and AIDS Prevention. It is to be given to all teachers who receive training as part of the EI/WH... more

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RCCE Action Plan Guidance COVID-19 Preparedness and Response
recommended

World Health Organization WHO; UNICEF; IFRC (2020) C_WHO

Risk Communication and Community Engagement (RCCE) is an essential component of your health emergency preparedness and response action plan. This tool is designed to support risk communication, community engagement staff and responders working with national health authorities, and other partners to ... more

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COVID-19! Comment puis-je me protéger et protéger les autres ?

Smithsonian Science Education Center (2020) C1

Ce programme vous aidera, vous et votre communauté, à comprendre la science du virus qui cause le COVID-19 et d'autres virus similaires. Il vous aidera à comprendre comment ce virus vous affecte ou pourrait vous affecter à l'avenir. Elle vous aidera à comprendre les mesures que vous pouvez pren... more

Menstrual Hygiene Management recommended

RCCE Action Plan Guidance COVID-19 Preparedness and Response recommended

Menstrual Hygiene Management
recommended

RCCE Action Plan Guidance COVID-19 Preparedness and Response
recommended