WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines.
Updated risk rates for hospital admission in patients with non-severe COVID-19
The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19.
The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients.
This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines:
**High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%.
**Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%.
Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk.
Review of COVID-19 treatments for people with non-severe COVID-19
WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022.
If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead.
WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission.
For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol.
WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials.
The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials.
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The 12th Meeting of the Regional Certification Commission (RCC) for the Polio Endgame in the Region of the Americas was conducted virtually due to the pandemic of COVID-19. The meeting was composed of 5 steps:
Step 1: An introductory meeting between RCC members and Secretariat
Step 2: Assessment... of the annual and containment reports by the reviewers
Step 3: Observations and recommendations review
Step 4: A meeting between RCC Chair and the Secretariat to review the draft report and general recommendations of the meeting
Step 5: RCC meeting to review and approve the recommendations to each country and the final report and recommendations of the meeting
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Good mental health is integral to human health and well being. A person’s mental health and many common mental disorders are shaped by various social, economic, and physical environments operating at different stages of life. Risk factors for many common mental disorders are heavily associated wit...h social inequalities, whereby the greater the inequality the higher the inequality in risk.
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This document is intended to serve as a reference for national public health policy-makers. It outlines the scope of potential meningitis surveillance strategies that make it possible to obtain the data required for epidemic detection, monitoring of epidemiological and microbiological trends, evalua...tion of meningitis control strategies and assessment of the impact of Nm A conjugate vaccine. Ultimately, it provides information that can be used to decide on a surveillance strategy that is tailored to the needs and capacity of a country.
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This report describes the work done by WHO from January 2015 up to the end of December 2016 to address the long-term issues of survivor care, health-systems strengthening and research.
Rev Saude Publica. 2022; 56: 22.
Published online 2022 Apr 11. doi: 10.11606/s1518-8787.2022056004040
Archives of Disease in Childhood 2021;106:238-240.
In January 2018, over 10,000 people fled their homes following clashes reported in multiple locations in Jonglei, including Yuai, Pultruk, Payai, Kuer-nyuon, Pieri, Waat and Walgak. Some crossed to
Ethiopia, where 2,300 people registered as refugees in the Gambela region. There were several report...s of people returning from displacement camps and refugee settlements in Uganda to locations in
Central Equatoria, including Lainya, Kajo-keji, Morobo and Yei, as well as reports of movement from Sudan to Bentiu, Unity. However, partners are working to verify these reports; population movements
remain difficult to track and patterns hard to discern. About 5.1 million people were estimated to be severely food insecure between January and March 2018, including 20,000 who are facing catastrophic conditions. According to assessments conducted in January in the Baggari area, Wau County, malnutrition has improved compared to the same period last year, with surveys showing GAM rates of
about 2.8 per cent in Mboro and 3.6 per cent in Farajallah. Last year, Baggari was among locations which surpassed the WHO emergency threshold of 15 percent of the population malnourished. In
January, there were no new reports of cholera cases in South Sudan, marking a continued decline in the outbreak that was declared in June 2016.
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Адаптивные технологии развития интеллектуальных способностей человека учитывают естественные интересы людей разных возрастных групп, позволяют оптимизировать ...интеллектуальные процессы, перекодировка информации обучает человека думать. Чем лучше мозг кодирует информацию, тем лучше запоминает. Основные характеристики адаптивных технологий развития интел-лектуальных способностей человека через единственный путь – скорочтение – рассматриваются в разрезе практических и прикладных рекомендаций, которые позволяют ученику овладеть различными видами чтения.
Accessed on 2019
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Indian Journal of Psychiatry 56(3), Jul‐Sep 2014; DOI: 10.4103/0019-5545.140615
Care and Support Centre (CSC) is a national initiative to provide expanded and holistic care and support services for PLHIV. The guideline focuses on the objectives, criteria for selection, required infrastructure, human resources, MIS tools, and financial guidelines for CSCs. This guideline will b...e useful to the care providers, programme managers, and all stakeholders in providing excellent care to the people living with HIV/AIDS
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