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Shorter treatment for children with minimal TB

SHINE Medical Research Council Clinical Trials Unit (MRC CTU) at UCL (2022) CC
The results of the SHINE trial have been published in the NEJM today. SHINE looked at whether treatment for children with minimal TB could be reduced from 6 months to 4 months. It found that the four month treatment was as good as the standard six months treatment for children with minimal TB
There is little doubt that 2019 was a defining year on many fronts for the environment. The repercussions of the climate emergency were experienced across the globe, with floods, devastating wildfires, and unprecedented melting of polar ice sheets and glaciers. While the new decade began with the Au ... more
WHO's Health in the Green Economy sector briefings examine the health impacts of climate change mitigation strategies considered by the Intergovernmental Panel on Climate Change in their Fourth Assessment Report (Climate Change, 2007). Large, immediate health benefits from some climate change strate ... more
The Lancet Planetary Health Volume 5, ISSUE 7, e466-e478, July 01, 2021 Transmission of many infectious diseases depends on interactions between humans, animals, and the environment. Incorporating these complex processes in transmission dynamic models can help inform policy and disease control int ... more
The “Wuppertal Call” – Contributions and Recommendations from an International Conference on Eco-Theology and Ethics of Sustainability Wuppertal, Germany, 16 – 19 June 2019
While “sustainability” has become a central aspect of social action and responsibility around the world, its complex and multi-di- mensional nature requires further explanation.
Today, WFP has the capabilities and know-how to tap into mobile technology and artificial intelligence to monitor food security; use satellite technology to locate and track communities in need; and offer digital finance via blockchain technology to put consumer choices in the hands of our beneficia ... more
This report shows that frontier agriculture is a viable complement to conventional agriculture, particularly in Africa and countries affected by fragility, conflict, and violence (FCV).
Current Environmental Health Reports volume 7, pages 363–370 (2020) Climate change has direct impacts on human health, but those impacts vary widely by location. Local health impacts depend on a large number of factors including specific regional climate impacts, demographics and human vulnerabil ... more
The new review paper, The Impacts of Climate Change on Health, identifies the extent to which increasing emissions, extreme weather and temperatures elevate health risks, from infectious disease to malnutrition, and assesses the associated health burden. It concludes that the health burden will exce ... more
17 March 2022
The Updated guidelines on Management of tuberculosis in children and adolescents include new recommendations that cover diagnostic approaches for TB, shorter treatment for children with non-severe drug-susceptible TB, a new option for the treatment of TB meningitis, the use of bedaquiline and delama ... more
Climate change presents significant challenges to human health and biodiversity. Increased numbers of extreme climate events, such as heat waves, droughts or flooding, threaten human health and well-being, both directly and indirectly, through impaired ecosystem functioning and reduced ecosystem ser ... more
A framework to implement the Agenda for the Americas on Health, Environment, and Climate Change 2021–2030
Children without access to safe water are more likely to die in infancy -- and throughout childhood -- from diseases caused by water-borne bacteria, to which their small bodies are more vulnerable.