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Topics in Antiviral Medicine, volume 33 Issue 2 May 2025
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public
...
ation contains recommendations that are from previously published WHO guidelines documents on advanced HIV disease and introduces new recommendations that were developed in 2025.
more
Core Guidance. Differentiated service delivery is highlighted as a key approach for HIV programmes to enhance implementation quality and efficiency.
A toolkit for health facilities. This toolkit highlights successful differentiated-care approaches implemented in a number of settings and countries in sub-Saharan Africa. The toolkit will be further updated as more experience is gained with these and similar
approaches
In: Antenatal Care, Maternal Care, Under 5 Clinics, Family Planning Clinics and HIV Exposed Child Follow Up.
This 5th Edition of the Malawi Guidelines for Clinical Management of HIV in Children and Adults is implemented from January 2022. It replaces all previous editions of the Malawi Antiretrovir
...
al therapy (ART) and Prevention of Mother to Child Transmission (PMTCT) guidelines.This document is written for medical doctors, clinical officers, medical assistants, nurses, midwives, laboratorians, health surveillance assistants (HSAs) and medical records clerks who are working in public and private sector health facilities in Malawi. It is designed to be a practical guide for implementation of integrated HIV Services
more
Essential triple EMTCT services include testing for HIV, syphilis and HBV in ante-
natal care (ANC) settings; prompt and efficacious interventions to treat women
who test positive; prevent transmission of any of the infections to their children;
counseling for women and their partners to reduce t
...
ransmission risk and ensure
appropriate treatment; encourage clean and safe delivery; appropriate follow
up of exposed infants including provision of HBV vaccine birth dose; promoting
optimal infant-feeding; and lifelong treatment and care for mothers living with
HIV or those eligible for treatment for hepatitis B infections and treatment for
syphilis.
more
Technical Document
The adopted pillars for the AEVT Plan are a) early testing among children exposed to HIV, syphilis and HBV; b) closing the treatment gap among PBFW and children exposed to HIV, syphilis and HBV; c) prevention of new HIV, syphilis and HBV infections among PBFW; and d) breaking down barriers to access
...
to integrated services. Based on these pillars, the AEVT plan guides galvanizing political advocacy for the last mile toward the elimination of vertical transmission of HIV, syphilis and HBV in Africa by 2030
more
a comprehensive guide
for the HCPs who work in counselling and psychological care of children and adoles-
cents. The Handbook includes information on HIV clinical care; growth and development;
mental health; child protection; counselling and communication; disclosure; loss, grief,
and bereavemen
...
t; adherence; sexual and reproductive health; transition of care; support
systems; and monitoring and evaluation of psychosocial services. The material provided
in the Handbook aims to equip HCPs with important information that will help them to
maximise resiliency, minimise risk factors, and promote positive personal growth among
the children and adolescents they care for who are living with or affected by HIV.
more
The Guide on HIV Services for Adolescents Living with HIV (ALHIV) describes
organization of adolescent-friendly services to guide heath management teams and health
care workers (HCWs) on their roles. It also outlines important aspects to consider when
offering comprehensive care to adolescents an
...
d their parents/caregivers at health facilities
and in the community. Comprehensive care should include the provision of quality clinical
and psychosocial support (PSS) services with clear linkages to the community. These
services need to be adolescent-friendly at any health facility with clear prescription of
minimal standards, and has to be integrated into existing services at the health facility
more
This comprehensive analysis outlines the recommended mental health services in HIV
care, delivery modalities, required resources, guideline integration, special population
considerations, and implementation strategies with real-world examples
This training seeks to equip health workers who have contact with children in HIV settings with the knowledge and skills to better integrate violence against children (VAC) services into their work. It seeks to transmit information and skills to make them: feel comfortable talking with, providing se
...
rvices and making appropriate referrals to children and their caregivers who are at risk of or experiencing violence.
This three-day training package includes ten modules to be delivered to groups of 25-30 health workers. The training is aimed at different cadres of health workers, including: nurses and midwives; clinicians; HIV counselors; medical social workers; pharmacists; community health workers, and others who are involved in children’s health care in health settings
more
A Clinical Guideline for the Diagnosis and Treatment of Drug-susceptible TB in Children and Adolescents
in South Africa. This new guidance is aligned with the updated WHO guidelines but has been adapted specifically for the South African context.
The intention of this publication is to provide g
...
uidance on the Diagnosis and treatment of TB in children and adolescents and they may be downloaded and distributed as required. Distribution for remuneration is not permitted. No changes to the content or format of this publication is permitted.
more
Ces orientations opérationelles ont pour but de soutenir les pays dans le processus d’introduction d’un antibiotique. Leur objectif est de garantir un accès rapide aux antimicrobiens et l’utilisation appropriée de ces produits ainsi que des résultats optimaux pour les patients, tout en ré
...
duisant le risque de résistance émergente, en offrant des conseils sur la manière d’introduire un antibiotique dans les systèmes de santé nationaux. Elles se concentrent principalement sur les antibiotiques relevant des groupes de classification « Watch » (utilisation sélective) et « Reserve » (dernier recours), qui sont généralement utilisés comme traitements de deuxième et troisième intention en milieu hospitalier. Ceux-ci sont essentiels pour traiter les organismes multirésistants mais sont souvent confrontés à des difficultés spécifiques en matière d’accès, en particulier dans les pays à revenu faible ou intermédiaire. Les présentes orientations décrivent une approche de planification pour l’introduction et la mise en oeuvre de ces produits, en tenant compte de leurs caractéristiques uniques et des besoins connexes, dans le but d’améliorer l’accès au traitement pour les patients et de promouvoir globalement l’utilisation appropriée des antibiotiques.
more
This report describes efforts in nine countries, supported by the 2gether 4 SRHR programme and other partners, highlighting the results achieved and learning on improving the health and wellbeing of adolescent and young mothers and their families. Key insights include the importance of responsive se
...
rvice delivery and social support as well as service provision across sectors.
more
2024 Global HIV Estimates on children, adolescents and pregnant women.
Lwamaba, C., and S. Brar
United Nations International Children's Emergency Fund UNICEF
(2024)
C_UNICEF
Presentation Slides
Progress report and road map. Countries included in this report: Algeria, Afghanistan, Bahrain, Djibouti, Egypt, the Islamic Republic of Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Morocco, Oman, Pakistan, Qatar, State of Palestine, Saudi Arabia, Somalia, Sudan, the Syrian Arab Republic, Tunisia, Un
...
ited Arab Emirates, Yemen.
To support countries in the region to achieve triple elimination goals, this report collects and assesses national policies and key indicators on EMTCT efforts against WHO criteria for validation of the EMTCT of HIV, syphilis and HBV. Based on analysis and consultations with national policymakers, the report provides a Road Map for countries at different stages of readiness to follow towards triple elimination goals.
more
This document aims to provide Ministry of Health guidance on the implementation of PEP and PrEP to prevent HIV transmission and improve overall health outcomes. This comprehensive approach reflects the commitment of all involved in combating HIV and enhancing public health.
This technical brief describes promising models that demonstrate how FBOs could contribute to expanded access to improved HIV and other services for men. These models incorporate a range of WHO-recommended interventions and highlights operational considerations and key success factors. By capitalizi
...
ng on their strengths, FBOs can potentially serve as useful platforms for engaging men and other priority populations, promoting greater demand, uptake, and retention in care.
more
A service guide for site operations
