This Review summarizes many of the persistent biological alterations associated with childhood maltreatment including changes in neuroendocrine and neurotransmitter systems and pro-inflammatory cytokines in addition to specific alterations in brain areas associated with mood regulation. Finally, I d...iscuss several candidate gene polymorphisms that interact with childhood maltreatment to modulate vulnerability to major depression and PTSD and epigenetic mechanisms thought to transduce environmental stressors into disease vulnerability.
Neuron Review, vol. 89, March 2, 2016 pp.892-909
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Dissertationsubmitted for the degree of Doctor of Philosophy, Brunel University
Posttraumatic stress disorder (PTSD) in children and adolescents occurs as a result of a child’s exposure to one or more traumatic events: actual or threatened death, serious injury, or sexual violence. The victim may experience the event, witness it, learn about it from close family members or fr...iends, or experience repeated or extreme exposure to aversive details of the event. Potentially traumatic events include physical or sexual assaults, natural disasters, and accidents.
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Diese Studie liefert einschlägige Informationen aus erster Hand über die Lebenswirklichkeit von syrischen Kindern, die arbeiten müssen: in ihrem Heimatland, in den Nachbarstaaten oder in Europa. Der syrische Bürgerkrieg ist die schlimmste humanitäre Katastrophe unserer Zeit. Hunderttausende Men...schen – Erwachsene und Kinder – wurden getötet. Zwei Drittel aller Syrer haben ihr Zuhause und ihre Existenzgrundlage verloren. Millionen Syrer wurden aus ihrem Lebensumfeld gerissen und gezwungen, innerhalb ihres Landes oder in die Nachbarländer zu fliehen. Die enormen Auswirkungen auf andere Länder ziehen internationale Aufmerksamkeit auf sich. Diese richtet sich nicht nur auf die humanitäre Krise in den betroffenen Gebieten und Ländern, sondern auch auf deren wirtschaftliche und soziale Last. Das durch die verschiedenen Konfliktparteien verursachte Blutvergießen hält an, das Leid wird größer. Rund die Hälfte aller syrischen Flüchtlinge und Vertriebenen sind Kinder und Jugendliche: Diese sind doppelt verletzlich – als Kinder und als Flüchtlinge oder Vertriebene.
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The National Disaster Management Plan (NDMP) provides a framework and direction to the government agencies for all phases of disaster management cycle. The NDMP is a “dynamic document” in the sense that it will be periodically improved keeping up with the emerging global best practices and knowl...edge base in disaster management. It is in accordance with the provisions of the Disaster Management Act, 2005, the guidance given in the National Policy on Disaster Management, 2009 (NPDM), and the established national practices.
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Antimicrobial resistance is a global threat as it is present in all parts of the world and it means that there is a shortage of effective antibiotics to treat simple infections and diseases, also statistics reveal that because of antimicrobial resistance patients’ morbidity and mortality is increa...sed, as well as healthcare related expenditures. Theoretical frameworks chosen for this study are Mark Salmon White’s construct for public health nursing and Tannahill’s model for health promotion. Both models focus on promoting and contributing to the health and well-being of the public. In this thesis the nurse’s role is explored and steps that can be taken towards contributing to minimizing antimicrobial resistance are listed
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A guide to support implementation of health service Quality Improvement activities in Ethiopian health facilities
This comprehensive book has established itself as the most useful text for the medical practitioner in poor-resource settings who is obliged to manage surgical cases. It is particularly adapted for those whose surgical experience is basic or minimal. Importantly, it has extensive advice about pitfal...ls to avoid, and what to do if things go wrong. It is written in simple style, particularly for those whose mother tongue is not English. It is not a text which discusses the latest up-to-date technology, but it is not out-of-date being a synthesis of the best advice from a myriad of surgeons practicing for many years in low- and middle-income countries.
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