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Глобальная статистика свидетельствует о том, что бремя туберкулеза более актуально в городских регионах. Тем не менее, в тех странах, где большая часть населения п...оживает в сельской местности в условиях крайней нищеты, туберкулез является доминирующей проблемой среди сельских жителей. Бедность и ограниченный доступ к медицинским учреждениям и медицинским работникам значительно снижают способность людей с туберкулезом, проживающих в сельской местности, получить своевременную диагностику и лечение.
Accessed on 2019more
We systematically reviewed Medline as well as the references of published review articles for relevant studies of adherence to multidrug treatment of both drug-susceptible and drug-resistant TB through February 3, 2018. We included randomized controlled trials (RCTs) as well as prospective and retro...spective cohort studies (CSs) with an internal or external control group that evaluated any adherence intervention and conducted a meta-analysis of their impact on TB treatment outcomes. Our search identified 7,729 articles, of which 129 met the inclusion criteria for quantitative analysis. Seven adherence categories were identified, including DOT offered by different providers and at various locations, reminders and tracers, incentives and enablers, patient education, digital technologies (short message services [SMSs] via mobile phones and video-observed therapy [VOT]), staff education, and combinations of these interventions.
https://doi.org/10.1371/journal.pmed.1002595more
Временные рекомендации
13 марта 2020 г.
Настоящий документ является вторым изданием руководства (версия 1.2), которое первоначально представляло собой адаптированн...ый вариант Руководства по клиническому ведению тяжелой острой респираторной инфекции при подозрении на инфекцию MERS-CoV (ВОЗ, 2019 г.).more
Научная справка
24 апреля 2020 г.
При инфицировании в естественных условиях выработка иммунитета к патогенному микроорганизму проходит в несколько этапов и заним...ет от 1 до 2 недель. При вирусной инфекции врожденный иммунитет обеспечивает немедленную реакцию организма, которая заключается в активации неспецифического иммунного ответа, приводящего к замедлению инфекционного процесса макрофагами, нейтрофилами и дендритными клетками, и которая в ряде случаев обусловливает бессимптомное течение инфекции. Затем происходит активация адаптивного иммунного ответа, при котором в организме начинается выработка специфических антител, способных к связыванию с вирусными частицами. Данные антитела являются белками и носят название иммуноглобулинов. Кроме того, в организме образуются Т-клетки, способные распознавать и уничтожать другие клетки, пораженные вирусом. Это звено иммунитета носит название клеточного. Функционирование нескольких звеньев иммунитета при адаптивном ответе может способствовать элиминации вируса из организма, а при достаточной активности реакции – препятствовать переходу заболевания в тяжелую форму и повторному заражению той же инфекцией. Количественной мерой данного процесса является уровень антител в крови.more
Este documento dá orientações sobre o uso de máscaras na comunidade durante a assistência domiciliar e em serviços de saúde em regiões que têm relatado casos de COVID-19. É dirigido a indivíduos na comunidade, profissionais de saúde pública e de prevenção e controle de infecção (PCI...), administradores da saúde, profissionais de saúde e trabalhadores da saúde comunitária. O documento será revisado à medida que mais dados se tornarem disponíveis.more
Цель настоящего документа - дать указания по очистке и дезинфекции поверхностей окружающей среды в контексте КОВИД-19. Настоящее руководство предназначено для раб...тников здравоохранения, специалистов в области общественного здравоохранения и органов здравоохранения, которые разрабатывают и осуществляют политику и стандартные оперативные процедуры (СОП) по очистке и дезинфекции поверхностей окружающей среды в контексте КОВИД-19.
Переведено с помощью www.DeepL.com/Translator (бесплатная версия)more
The package provides practical, concise yet crucial information about the impact of COVID-19 on daily teaching practices as well as tips and suggestions to improve safety, well-being and learning, with students in face-to-face or remote settings.
The package speaks directly to the teachers. It ca...n be adapted to their context and can be completed at the teachers’ own pace. It includes quizzes and a self-evaluation and planning tool to help teachers reflect on what they learned and what they still need to learn, encouraging them to keep learning!more
21 August 2020
This guidance provides specific considerations for the use of non-medical masks, also known as fabric masks, by children as a means for source control in the context of the current COVID-19 pandemic. It also advises on the use of medical masks for children under certain conditions.
interim Guidance 1 December 2020. Updated version
This document provides updated guidance on mask use in health care and community settings, and during home care for COVID-19 cases. It is intended for policy makers, public health and infection prevention and control professionals, health care manag...ers and health workers.
The Annex provides advice on how to manufacture non-medical masks. It is intended for those making non-medical masks at home and for mask manufacturersmore