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Mycetoma is a chronic, progressively destructive infectious disease of the subcutaneous tissues, affecting skin, muscle and bone. Mycetoma occurs in tropical and subtropical environments characterized by short rainy seasons and prolonged dry seasons
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that favour the growth of thorny bushes. Global burden is not known, but the disease is endemic; it has been reported from countries in Africa, Asia, Europe and Latin America. This course addresses the epidemiology of mycetoma, clinical features, diagnosis, treatment, and public health interventions.
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The aims of this publication is to highlight the lack of diversity in medical literature and education
Noma (cancrum oris) is a serious gangrenous disease of the mouth and face, mainly affecting children aged 2 to 6 years in sub-Saharan Africa.
Despite substantial knowledge gaps, it is reported to be linked with malnutrition, poor oral hygiene, immunosuppression, and living in extreme poverty situ
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ations.
This course addresses epidemiology, pathogenesis, clinical features, diagnosis, treatment, and public health considerations, including the human rights perspective of noma.
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Onchocerca volvulus transmitted by repeated bites of infected blackflies (Simulium spp.). These blackflies breed along fast-flowing rivers and streams, close to remote villages located near fertile land where people rely on agriculture.
There is a need to reinforce skills of national and district
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health workers to know and identify the disease, understand the risk factors according to the context and living conditions of the affected communities, and promote the implementation of public health interventions. With the shift from control to elimination, large areas in Africa require mapping to assess whether transmission is active, and treatment required. A sampling strategy named Onchocerciasis elimination mapping has been developed to help countries conduct those assessments and start treatment where needed.
This course examines the epidemiology of Onchocerciasis, clinical aspects, impact, diagnosis, treatment and control, elimination, public health interventions and role of community health workers
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Course information
Yaws is targeted for eradication by WHO in the 2021-2030 NTD Roadmap. It is therefore crucial to know how to identify cases, design and implement activities to eradicate the disease at the community level.
In the context of integration of
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skin NTDs it is vital to learn to recognize a disease targeted for eradication. At the individual level yaws lesions may mimic other skin diseases. At the community level, it is key to know how to design and implement the total community treatment strategy and monitor its impact. This course aims at providing health workers with the basic knowledge to understand the epidemiology, diagnosis, treatment, impact, eradication strategy and reporting of yaws.
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Pharmaceuticals 2024, 17(6), 691; https://doi.org/10.3390/ph17060691
Injury to the skin and underlying tissues from acute exposure to
a large external dose of radiation is referred to as cutaneous
radiation injury (CRI). Acute radiation syndrome (ARS) 1 will
usually be accompani
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ed by some skin damage; however, CRI
can occur without symptoms of ARS. This is especially true with
acute exposures to beta radiation or low-energy x-rays, because
beta radiation and low-energy x-rays are less penetrating and less
likely to damage internal organs than gamma radiation is. CRI can
occur with radiation doses as low as 2 Gray (Gy) or 200 rads 2 and
the severity of CRI symptoms will increase with increasing doses.
Most cases of CRI have occurred when people inadvertently came
in contact with unsecured radiation sources from food irradiators,
radiotherapy equipment, or well depth gauges. In addition, cases of
CRI have occurred in people who were overexposed to x-radiation
from fluoroscopy units.
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Yaws is a chronic skin infection characterized by papillomas (noncancerous lumps) and ulcers. It is caused by the bacterium Treponema pallidum subspecies pertenue, which belongs to the same group of bacteria that causes venereal syphilis.
Onchocerciasis causes skin and eye disease, visual impairment and neurological problems. It is mostly found in Africa, but also in Latin America and Yemen. The common name, ‘river blindness,’ gives a good indication where the disease can be foun
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d: the vector of the parasite, a small black fly of the Simulium species, breeds in rivers where there is turbulence in the water, such as rapids, or where the flow is disturbed by overhanging vegetation.
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Scabies is a contagious skin condition caused by tiny mites that burrow into the skin.
The main symptom of scabies is intense itching that's worse at night. It also causes a
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skin rash on areas where the mites have burrowed.
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Scabies is a contagious skin condition caused by the mite Sarcoptes scabiei which burrows into the skin and causes severe itching. Scabies is transmitted by direct
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skin-to-skin contact or indirectly by contact with contaminated material (fomites). This condition is often challenging to diagnose as many patients may have only subtle symptoms. However, other patients may present with the classic history of exposure, severe pruritis that is worse at night, and reference to other individuals with similar symptoms. This activity reviews the evaluation and treatment of scabies and highlights the role of the interprofessional team in managing patients with this condition.
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Scabies is an itchy skin condition caused by a tiny burrowing mite. This eight-legged bug is so small which makes it hard to see on the skin. Approximately 300 million cases of scabies are reported
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worldwide each year.
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Yaws is a chronic tropical skin disease that mainly affects children in remote, tropical and often impoverished areas. The disease presents with highly infectious lesions of the skin which can sprea
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d to the cartilage and bone. It is one of three endemic treponenatoses and is caused by the spirochete bacteria Treponema pallidum subsp. pertenue. Under the proposed World Health Organization’s new NTD Roadmap 2030, yaws has been targeted for global eradication by 2030.
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Scabies is an infestation of the skin by the human itch mite (Sarcoptes scabiei var. hominis). The microscopic scabies mite burrows into the upper layer of the skin where it lives and lays its eggs.
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The most common symptoms of scabies are intense itching and a pimple-like skin rash. The scabies mite usually is spread by direct, prolonged, skin-to-skin contact with a person who has scabies.
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Buruli ulcer is a disease of skin and soft tissue with the potential to leave sufferers scarred and disabled. It is caused by an environmental pathogen, Mycobacterium
ulcerans, that produces a destructive toxin. The exact mode of transmission is u
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nclear. The main burden of disease falls on children living in sub-Saharan Africa, but healthy people of all ages, races, and socioeconomic classes are susceptible.
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Buruli ulcer (BU) is a bacterial skin infection that is caused by Mycobacterium ulcerans and mainly affects people who reside in the rural areas of Africa and in suburban and beach resort communities in Australia.
Buruli ulcer (BU) is a skin-related neglected tropical disease (skin NTD) caused by infection with
Mycobacterium ulcerans. BU is the third most common mycobacterial disease after tuberculosis and l
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eprosy
in people who are not immunocompromised. The infection manifests in non-ulcerative forms as nodules,
plaques and/or oedemas, which ulcerate within 4–6 weeks and display characteristic undermined edges and yellowish-white necrotic slough . Most lesions occur on the lower limbs.
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Chromoblastomycosis (CMB) is a chronic fungal infection of the skin and the subcutaneous tissue caused by a transcutaneous traumatic inoculation of a specific group of dematiaceous fungi occurring mainly in tropical and subtropical zones worldwide.
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If not diagnosed at early stages, patients with CBM require long term therapy with systemic antifungals, sometimes associated with physical methods. Unlike other neglected endemic mycoses, comparative clinical trials have not been performed for this disease. Nowadays, therapy is based on a few open trials and on expert opinion. Itraconazole either as monotherapy or associated with other drugs, or with physical methods, is widely used. Recently, photodynamic therapy has been successfully employed in combination with antifungals in patients presenting with CBM. In the present revision the most used therapeutic options against CBM are reviewed as well as the several factors that may have impact on the patient's outcome.
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Scabies is caused by Sarcoptes scabiei, a mite which lays its eggs under the surface of your skin and reproduces. When the eggs hatch, mites crawl out onto your skin and make new burrows.
The mites
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can be difficult to identify and may be confused with pubic lice as both conditions cause itching in the genital area.
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Human scabies is caused by an infestation of the skin by the human itch mite (Sarcoptes scabiei var. hominis). The microscopic scabies mite burrows into the upper layer of the skin where it lives an
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d lays its eggs.
Scabies is found worldwide and affects people of all races and social classes. Scabies can spread rapidly under crowded conditions where close body and skin contact is frequent. Institutions such as nursing homes, extended-care facilities and prisons are often sites of scabies outbreaks. Child care facilities also are a common site of scabies infestations.
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