Cardiovascular diseases are the world’s leading cause of disability and death. Such diseases were responsible in 2019 for an estimated 18.6 million deaths globally and 957,000 deaths in the United States.
Secondhand smoke and the harmful chemicals in it are known causes of Sudden Infant Death Syndrome RESPIRATORY INFECTIONS, ear infections.and asthma attacks in infants and children. They are also known causes of HEART DISEASE,stroke, and lung cancer in adult nonsmokers.
Video :Health Pot about Prevention, Genetic Test, Prevention of Air Pollution and Spirometry.
The Noncommunicable Diseases Country Profiles 2018 by the World Health Organization (WHO) provides an in-depth look at the burden of noncommunicable diseases (NCDs) such as cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes across WHO Member States. It includes data on NCD m...ortality, risk factors like tobacco use, unhealthy diets, physical inactivity, and excessive alcohol consumption, as well as country-specific responses and health system capacities to manage and prevent NCDs.
more
Outdoor air pollution is one of the world's largest health and environmental problems. The Global Burden of Disease is a major global study on the causes and risk factors for death. These estimates of the annual number of deaths attributed to a wide range of risk factors are shown here. This chart i...s shown for the global total but can be explored for any country or region using the "change country or region" toggle.
more
Severe and difficult asthma in a low- and middle-income country (LMIC) can relate to lack of availability of basic medications; potentially reversible factors such as poor adherence or comorbidities such as obesity inhibiting a good response to treatment; and (rarely) true severe, therapy-resistant ...asthma. However, definitions of severity should encompass not merely doses of prescribed medication, but also underlying risk. The nature of asthmatic airway disease shows geographical variation, and LMIC asthma should not be assumed to be phenotypically the same as that in high-income countries (HICs). The first assessment step is to ensure another diagnosis is not being missed. Largely, political action is needed if children with asthma are to get access to basic medications. If a child is apparently not responding to low dose, simple medications, the next step is not to increase the dose but perform a detailed assessment of what factors (for example co-morbidities such as obesity, or social factors like poor adherence) are inhibiting a treatment response; in most cases, an underlying reason can be found. An assessment of risk of future severe asthma attacks, side-effects of medication and impaired lung development is also important. True severe, therapy-resistant asthma is rare and there are multiple underlying molecular pathologies. In HICs, steroid-resistant eosinophilia would be treated with omalizumab or mepolizumab, but the cost of these is prohibitive in LMICs, the biomarkers of successful therapy are likely only relevant to HICs. In LMICs, a raised blood eosinophil count may be due to parasites, so treating asthma based on the blood eosinophil count may not be appropriate in these settings.
more
PATS and ERS
Paediatric Webinar Series
Air pollution and the lung in children:
the evidence for exposure and prevention measures
There is increasing interest in understanding the role of air pollution as one of the greatest threats to human health worldwide. Nine of 10 individuals breathe air with polluted compounds that have a great impact on lung tissue. The nature of the relationship is complex, and new or updated data are... constantly being reported in the literature. The goal of our review was to summarize the most important air pollutants and their impact on the main respiratory diseases (chronic obstructive pulmonary disease, asthma, lung cancer, idiopathic pulmonary fibrosis, respiratory infections, bronchiectasis, tuberculosis) to reduce both short- and the long-term exposure consequences. We considered the most important air pollutants, including sulfur dioxide, nitrogen dioxide, carbon monoxide, volatile organic compounds, ozone, particulate matter and biomass smoke, and observed their impact on pulmonary pathologies. We focused on respiratory pathologies, because air pollution potentiates the increase in respiratory diseases, and the evidence that air pollutants have a detrimental effect is growing. It is imperative to constantly improve policy initiatives on air quality in both high- and low-income countries.
more
In spite of the work carried out by the EU institutions, the Member States, many cities and grassroot movements in Europe, the general public is still not engaging enough in air quality policy initiatives and the level of awareness and knowledge of the effects of poor air quality on health is often ...low.
HEAL, within its work with the EU urban air quality partnership has put together a toolkit on ‘Communicating on air quality and health – Inspiring practices, challenges and tips’, providing hands-on examples of how communication on air quality, the health links and (policy and behavioural) changes takes place, as an inspiration particularly for urban authorities wanting to communicate on clean air.
The Partnership on Air Quality was founded in 2016 with the main objective of improving air quality in cities and bringing the ‘healthy city’ higher on the local, national and EU agendas as part of the urban agenda.
more
Everyone in the world is exposed to risk factors for chronic respiratory disease (CRD). Three billion people live in urban areas and are exposed to outdoor air pollution. Two billion people are exposed to solid fuel combustion which represents one of the major risk factors worldwide. One billion peo...ple are exposed to tobacco smoke and everyone is exposed to allergens. These risk factors are of particular concern in developing countries and deprived areas.
more
The World Health Organization (WHO) highlights the significant health risks associated with household air pollution, primarily resulting from the use of inefficient and polluting fuels and technologies for cooking, heating, and lighting. In 2020, approximately 2.1 billion people—about one-third of... the global population—relied on open fires or inefficient stoves fueled by kerosene, biomass (such as wood, animal dung, and crop waste), and coal. This exposure led to an estimated 3.2 million deaths, including over 237,000 deaths of children under the age of five. The pollutants emitted from these sources contribute to a range of health issues, including respiratory infections, heart disease, stroke, chronic obstructive pulmonary disease, and lung cancer. The WHO emphasizes the urgent need for transitioning to cleaner fuels and technologies to mitigate these health risks.
more
The Our World in Data webpage on air pollution provides an extensive overview of the global impact of air pollution on health and the environment. It presents data on sources of pollution, such as industry, vehicles, and domestic energy use, and highlights the associated health risks, including resp...iratory and cardiovascular diseases. The site emphasizes that air pollution is one of the leading environmental risk factors for premature deaths worldwide, particularly affecting low- and middle-income countries. It also discusses trends in air pollution levels over time and the effectiveness of policy interventions in reducing pollution and improving public health.
more
Silicosis is not a new disease; the impact of silica dust on respiratory function was observed by Hippocrates in 430 B.C. and in the 16th century by Agricol. In 1713, Rammazini described silicotic nodules in post-mortems of stone cutters presenting with respiratory symptoms. In the mid-late 1800s,... the introduction of mechanized tools in the mining sector rapidly increased levels of silica exposure, resulting in an increase in cases and our understanding of silicosis.
more
Air pollution is the top environmental threat to health in Europe. It leads to hundreds of thousands premature deaths per year and billions of Euros in health costs.
BACKGROUND. Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, as well as airway reversibility. The burden of asthma in children is increasing in low- and middle-income countries and remains under-recognised and poorly managed.
OBJE...CTIVES. To quantify the burden of asthma in the South African (SA) population and identify the risk factors associated with disease severity in the local context.
METHODS. The SA Childhood Asthma Working Group (SACAWG) convened in January 2017 with task groups, each headed by a section leader, constituting the editorial committee on assessment of asthma epidemiology, diagnosis, control, treatments, novel treatments and self-management plans. The epidemiology task group reviewed the available scientific literature and assigned evidence according to the Grades of Recommendation Assessment, Development and Evaluation (GRADE) system.
CONCLUSIONS. Asthma in children remains a common condition, which has shown an increasing prevalence in urban and rural populations of SA. Of concern is that almost half of children in urban communities experience severe asthma symptoms, and many asthmatics lack a formal diagnosis and thus access to treatment. Exposure to tobacco smoke and living in highly polluted areas increase the severity of wheezing in young children.
more
Indoor air pollution is one of the world's largest environmental problems – particularly for the poorest in the world, who often do not have access to clean fuels for cooking.The Global Burden of Disease is a major global study on the causes and risk factors for death and disease. The study estima...tes of the annual number of deaths attributed to a wide range of risk factors are shown here. This chart is shown for the global total but can be explored for any country or region using the "change country or region" toggle.
more
Non-communicable diseases (NCDs) account for 72% of all deaths globally and this proportion is growing. Greatest increases in NCD mortality are seen in low-income and middle-income countries (LMICs). Places that only a generation ago knew famine are
today experiencing epidemics of obesity, diabetes..., cardiovascular disease, and cancer. These epidemics reduce human capital in developing countries and their economic costs are so great that they threaten to slow and even undercut trajectories of economic and social development.
more
The World Health Organization (WHO) fact sheet on ambient (outdoor) air quality and health highlights the significant health risks posed by outdoor air pollution. It reports that in 2019, ambient air pollution was responsible for approximately 4.2 million premature deaths globally, primarily due to ...exposure to fine particulate matter (PM2.5), which leads to cardiovascular and respiratory diseases, as well as cancers. The fact sheet emphasizes that 99% of the global population lived in areas exceeding WHO air quality guidelines in 2019, with low- and middle-income countries bearing the highest burden. To mitigate these health impacts, WHO advocates for policies and investments that promote cleaner transportation, energy-efficient housing, improved waste management, and access to clean household energy.
more
Although air pollution is well known to be harmful to the lung and airways, it can also damage most other organ systems of the body. It is estimated that about 500,000 lung cancer deaths and 1.6 million COPD deaths can be attributed to air pollution, but air pollution may also account for 19% of all... cardiovascular deaths and 21% of all stroke deaths. Air pollution has been linked to other malignancies, such as bladder cancer and childhood leukemia. Lung development in childhood is stymied with exposure to air pollutants, and poor lung development in children predicts lung impairment in adults. Air pollution is associated with reduced cognitive function and increased risk of dementia. Particulate matter in the air (particulate matter with an aerodynamic diameter < 2.5 μm) is associated with delayed psychomotor development and lower child intelligence. Studies link air pollution with diabetes mellitus prevalence, morbidity, and mortality. Pollution affects the immune system and is associated with allergic rhinitis, allergic sensitization, and autoimmunity. It is also associated with osteoporosis and bone fractures, conjunctivitis, dry eye disease, blepharitis, inflammatory bowel disease, increased intravascular coagulation, and decreased glomerular filtration rate. Atopic and urticarial skin disease, acne, and skin aging are linked to air pollution. Air pollution is controllable and, therefore, many of these adverse health effects can be prevented.
more
Air pollution is one of the leading causes of health complications and mortality worldwide, especially affecting lower-income groups, who tend to be more exposed and vulnerable. This study documents the relationship between ambient air pollution exposure and poverty in 211 countries and territories.... Using the World Health Organization’s (WHO) 2021 revised fine particulate matter (PM2.5) thresholds, we show that globally, 7.3 billion people are directly exposed to unsafe average annual PM2.5 concentrations, 80 percent of whom live in low- and middle-income countries. Moreover, 716 million of the world’s lowest income people (living on less than $1.90 per day) live in areas with unsafe levels of air pollution, especially in Sub-Saharan Africa. Air pollution levels are particularly high in lower-middle-income countries, where economies tend to rely more heavily on polluting industries and technologies. These findings are based on high-resolution air pollution and population maps with global coverage, as well as subnational poverty estimates based on harmonized household surveys.
more