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This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical
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research activities – including site operations, participant travel, supply chains, data management and waste – and highlights how these impacts intersect with climate change risks to health systems and research infrastructure.
more
The aim of this document is to provide interim guidance for interventions to reduce the risk of maternal Zika virus infection and to manage potential complications during pregnancy. This guidance is based on the best available research evidence and
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covers areas prioritized by an international, multidisciplinary group of health care professionals and other stakeholders. Specifically, it presents guidance for preventing Zika virus infection;antenatal care and management of women with infection; and care during pregnancy for all pregnant women living in affected areas, with the aim of optimizing health outcomes for mothers and newborns.
more
This short paper aims to identify key evidence gaps in our knowledge of livestock- and fisheries-linked antimicrobial resistance in the developing world, and to document on-going or planned research initiatives on this topic by key stakeholders.
Th
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e antimicrobial resistant (AMR) infections in animals that are of most potential risk to human health are likely to be zoonotic pathogens transmitted through food, especially Salmonella and Campylobacter. In addition, livestock associated methicillin resistant Staphylococcus aureus (LA MRSA) and extended spectrum beta lactamase E. coli (ESBL E. coli) are emerging problems throughout the world.
more
The conduct of COVID-19 vaccine trials in the context of a candidate vaccine being issued with Emergency Use Designation raises challenging ethical questions, including in relation to the use of placebo controls and unblinding of trial participants in current and future COVID-19 vaccine trials. This
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policy brief was developed by the WHO Access to COVID-19 Tools (ACT) Accelerator Ethics & Governance Working Group, to provide guidance for researchers, sponsors, regulators, research ethics committees, and policy-makers, on these and related issues.
more
Evidence from a systematic review on antenatal zinc supplementation was evaluated as part of the World Health Organization (WHO) antenatal care (ANC) guideline development process in 2016, and the following recommendation on zinc supplementation was
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made: “Zinc supplementation for pregnant women is only recommended in the context of rigorous research.” The Guideline Development Group (GDG) made this recommendation because it felt that the evidence on the intervention was incomplete and that more research was necessary.
more
A manual for physicians and other senior health workers. This fourth revision of the manual reflects recent clinical experience and research findings in diarrhoea case management. Compared to earlie
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r versions, it includes revised guidelines on the management of children with acute diarrhoea using the new reduced (low) osmolarity ORS formulation and using zinc supplements, which have been shown to reduce duration and severity of diarrhoeal episodes, and revised guidelines for the management of bloody diarrhoea. Guidelines in the manual are based on the revised WHO chart that are included at the end of this document.
more
Health communication has proven to play a crucial role in addressing diseases such as dengue, Zika and chikungunya, for which there are no definitive or easily accessible vaccines. In this context, this discipline becomes a fundamental tool to promo
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te the change behavior and promote preventive practices that reduce the transmission of these diseases. By not having a definitive medical solution, accurate and timely information, effectively disseminated through educational campaigns, media and communication channels public health, can significantly influence individual and community actions to control the spread of these mosquito-borne viruses. The accumulated research around the threat of the aforementioned arboviral diseases brings together a series of recommendations around specific communication activities, such as disseminating timely and accurate information that integrates public health concerns and the needs of information of the population, especially vulnerable groups such as women of childbearing age, pregnant women and health workers.
more
WHO Model Formulary for Children
recommended
WHO Model Formulary for children based on the Second Model List of Essential Medicines for Children 2009.
In 2007, the World Health Assembly passed a Resolution titled ‘Better Medicines for Children’. This resolution recognized the need for
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research and development into medicines for children, including better dosage forms, better evidence and better information about how to ensure that medicines for treating the common childhood diseases are given at the right dose for children of all ages.
more
Please download the latest report from the official website:
http://www.nacp.go.tz/site/publications/epidemiology-and-research-coordination
Plan de acciόn sobre salud mental 2013-2020.
recommended
Four major objectives are set forth: more effective leadership and governance for mental health; the provision of comprehensive, integrated mental health and social care services in community-based
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settings; implementation of strategies for promotion and prevention; and strengthened information systems, evidence and research.
more
PAHO has systematically identified and collected basic information on all investigations related to Zika, both those already published and those on track to be published.
Each study has been categorized in the areas of virus, vectors and reservoirs; epidemiology; disease pathogenesis and consequen
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ces of Zika infection; clinical management; public health interventions; health systems and services response; research and product development; and causality. You can also search by publication type: published articles, protocol and publication of preliminary results.
more
Overuse and misuse of antibiotics in animals and humans is contributing to the rising threat of antibiotic resistance. Some types of bacteria that cause serious infections in humans have already developed resistance to most or all of the available treatments, and there are very
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few promising options in the research pipeline
more
This guidance document provides basic broad principles for a spokesperson
of any health authority on how to respond to vocal vaccine deniers.
The suggestions are based on psychological research on
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persuasion,
on research in public health, communication studies and on WHO risk
communication guidelines.
more
For biological agents, the publication covers 11 bacteria,
fungi and viruses listed by states parties to the Biological
Weapons Convention in declarations of past offensive
research and development programmes, or considered of
special concern fo
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r possible use in terrorism. All of these
agents can cause natural disease in humans, though with
markedly different frequency.
more
WHO regional publications. Western Pacific series ; no.3
The book has three main parts. The first part describes research in Viet Nam conducted on medicinal plants in line with the national policy of developing a system of medicine and pharmacy tha
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t integrates the modern and traditional systems. The second part, which constitutes the core of the book, describes and illustrates the 200 most valuable species of wild and cultivated medicinal plants in Viet Nam. Each plant species is first documented by a full colour drawing illustrating the plant's distinctive features and natural colours. Explanatory notes for each species provide a concise description of the plant and give local names, flowering period, geographical distribution, parts used, chemical composition, and therapeutic uses. Information on indications and dosage is also provided.
To facilitate retrieval of information, the third part indexes plant species according to botanical name, Vietnamese name, and English name.
Large File to download: 75 MB! more
To facilitate retrieval of information, the third part indexes plant species according to botanical name, Vietnamese name, and English name.
Large File to download: 75 MB! more
The number of general health staff skilled in psychological treatment for depression is limited, and learning psychological treatments tends to require considerable training and supervision. Relaxation may be a relatively simple form of psychologica
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l treatment. It has been frequently studied in research studies as an active condition and as a control condition.
Q 5: Is relaxation training better (more effective than/as safe as) than treatment as usual in adults with depressive episode/disorder?
more
Facing the global nutrition challenges, the World Health Organization (WHO) teamed up with the United Nations Institute for Training and Research (UNITAR) to design, under the guidance of the Depart
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ment of Nutrition for Health and Development (NHD), a Nutrition Knowledge Hub. By building the technical and functional capacities of all relevant staff at WHO through e-learning courses and key nutrition-related training and knowledge materials, the Nutrition Knowledge Hub aims to contribute to the acceleration and increase of the nutrition impact at the country level. The Nutrition Knowledge Hub also offers free and open courses to reach a larger public and raise awareness on the malnutrition problem and WHO’s response.
more
To help health- and social-system leaders as they respond to unprecedented challenges related to the COVID-19 pandemic, teams from the McMaster Health Forum and Ottawa Hospital
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Research Institute – as part of their contribution to RISE – and the Africa Centre for Evidence have compiled a list of evidence sources.
more
Project protocol
Introduction Ready-to-eat food sold in the street represents a global phenomenon, more common in urbanized areas, that constitutes an important dietary source in populations from low- and middle-income countries. However, research
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on the kind of street food offered and its composition is scarce. The main objective of this study is to characterize the urban street food environment, including vending places, the food offered, its nutritional composition, food purchasing patterns and advertising.
Methods and analysis This protocol provides a framework for a stepwise, standardized characterization of the street food environment; it consists of three steps that are of increasing complexity and demand increasingly great human and technical resources. Step 1 comprises identification of street food vending sites and characterization of the products available; this stage may be complemented with an evaluation of food advertising in the streets. Step 2 comprises description of street food purchasing patterns, by direct observation. Step 3 requires collection of food samples for bromatological analysis. Different levels of data collection may be defined for each step; hereafter, these are presented as core and expanded evaluations. For the most part, data analysis involves descriptive statistics and basic spatial analysis.
more
Vaccines explained
recommended
WHO's 'Vaccine Explained' series features illustrated articles on vaccine development and distribution. Learn more about vaccines from the earliest of research stages to their rollout in countries.
Availble in different languages