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1
WHO recommends artemisinin-based combination therapies for treating uncomplicated malaria, alongside studies to monitor treatment effectiveness. Given the threat of antimalarial resistance, including partial resistance in several African countries, molecular tools are vital for tracking resistance.
...
In 2015, WHO launched the External Quality Assessment scheme for nucleic acid amplification testing to ensure reliable lab results. Coordinated by WHO and operated by the United Kingdom National External Quality Assessment Service for Parasitology, the scheme provides quality-controlled specimens and reports to help improve testing accuracy. Experts recently discussed expanding the scheme to include antimalarial resistance markers.
more
WHO guidelines for clinical management of arboviral diseases: dengue, chikungunya, Zika and yellow fever
recommended
The new WHO guidelines provide clinical management recommendations for four of the most widespread arboviruses affecting humans: dengue, chikungunya, Zika, and yellow fever.
An integrated approach is vital, as these four diseases often present wi
...
th similar symptoms, especially in the early stages of infection, and multiple arboviruses may circulate simultaneously in certain regions. This makes clinical differentiation challenging, particularly where diagnostic testing is not readily available.
This guideline is available in online format on the MAGICapp platform
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This document is itended as a quick guide of healtcare workers involved in clincial management
The New England Journal of Medicine has a perspective on Ebola Virus Disease in West Africa — Clinical Manifestations and Management, written by authors who have cared for more than 700 patients with EVD between August 23 and October 4, 2014, in t
...
he largest Ebola treatment unit in Monrovia, Liberia (Free Access) NEJm, November 5, 2014DOI: 10.1056/NEJMp1413084
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WHO Pharmacovigilance indicators: a practical manual for the assessment of pharmacovigilance systems
This manual provides a practical method for determining the pharmacovigilance indices. It is designed to be simple and can be understood by any worker in pharmacovigilance without formal training in monitoring and evaluation. Pharmacovigilance as a medical discipline is crucial in preventing medicin
...
e-related adverse effects in humans, promoting patient safety, and the rational use of medicines. The indicators proposed in this manual are based on the expected functions of pharmacovigilance centres as described in the WHO Mimimum Requirements for a Functional Pharmacovigilance System (1) (see Annex 1 of the manual).
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Services, Identified needs and recommendations following the April and May 2015 Earthquakes in Nepal
Towards gender - transformative HIV and TB responses
На пути к гендерно-преобразовательным мерам против ВИЧ и ТБ
Review Article: Journal of Nutritional Health & Food Science
Vitamin Deficiency and Tuberculosis: Need for Urgent Clinical Page 1- 6
Review
S Afr Med J 2014;104(3):174-177. DOI: 10.7196/SAMJ.7968
Sexual violence is a major problem in South Africa, with studies showing that up to one in four women have been raped in their lifetime.
IPCAT2 will assist countries to determine the core components already in place, that is, existing strengths, and to identify gaps or weaknesses to guide action planning. IPCAT2 corresponds to the six core component recommendations of the guidelines targeted at the national level.
It is very impor
...
tant to understand that IPCAT2 is not intended to be used as an audit tool. Its purpose is to help assess, plan, organize and implement a national IPC programme. The tool provides a general overview of the status of IPC activities according to the guideline recommendations, rather than focusing on specific IPC practices/risk factors related to individual patients or specific.
more
In 2014, the Ministry of Health (MOH) in Malawi conducted a nationwide assessment of emergency obstetric and newborn care (EmONC) services. This cross-sectional facility-based survey used 10 data collection modules. Data collection began on 23rd Sep
...
tember 2014 and concluded on 17th October 2014, in all 28 districts. Facilities in both the public and private sector (for-profit and not-for-profit) were included. Since the focus of the assessment was obstetric and newborn care, health facilities that did not offer maternal and newborn health (MNH) services were not selected. In all districts, a census of all hospitals and a 60 percent random sample of health centres that ought to have performed deliveries in the previous year yielded a total of 365 facilities: 87 hospitals and 278 health centres. All these facilities were visited during the assessment. During analysis, weighting procedures were applied to extrapolate results to the district and national level, representing all 87 hospitals and 464 health centres. Such weighting was necessary as a stratified random sample of health centres was taken and weighting applied to all indicators and presentations that have health facility as a unit of measurement. Case reviews and provider’s interviews, on the other hand, are not weighted as their sampling strategy is based on convenience.
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Version 1.1 July 2016
The purpose of this document is to describe standard operating procedures for viral load monitoring, including the schedule for viral load testing when used for routine monitoring of children, adolescents and adults on ART; interpretation of results; patient management; an ... d specimen collection, preparation and transport. This template document to be adapted for use in various contexts and is one component of a viral load monitoring toolkit, to be used in conjunction with ICAP’s Viral Load Monitoring Flipchart and Enhanced Adherence Treatment Plan. more
The purpose of this document is to describe standard operating procedures for viral load monitoring, including the schedule for viral load testing when used for routine monitoring of children, adolescents and adults on ART; interpretation of results; patient management; an ... d specimen collection, preparation and transport. This template document to be adapted for use in various contexts and is one component of a viral load monitoring toolkit, to be used in conjunction with ICAP’s Viral Load Monitoring Flipchart and Enhanced Adherence Treatment Plan. more
The overall aim of the study was to understand the acceptability and usefulness of PHC clinical placements for nursing and midwifery students.
This Review summarizes many of the persistent biological alterations associated with childhood maltreatment including changes in neuroendocrine and neurotransmitter systems and pro-inflammatory cytokines in addition to specific alterations in brain areas associated with mood regulation. Finally, I d
...
iscuss several candidate gene polymorphisms that interact with childhood maltreatment to modulate vulnerability to major depression and PTSD and epigenetic mechanisms thought to transduce environmental stressors into disease vulnerability.
Neuron Review, vol. 89, March 2, 2016 pp.892-909
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