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The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level

Maguire, B.; Dahal, P.; Rashan, S. et al. PLoS Neglected Tropical diseases (2021) CC

Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses to address the many outstanding rese... more

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NCD Alliance Advocacy Priorities - For the 2023 United Nations High-Level Meeting on Universal Health Coverage

NCD Alliance NCD Alliance (2023) CC2

The document is a policy brief by the NCD Alliance for the 2023 United Nations High-Level Meeting on Universal Health Coverage (UHC). It highlights the importance of integrating non-communicable diseases (NCDs) into UHC efforts, with the goal of ensuring equitable health access worldwide.

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Women Cancer
recommended

Henke, A.; and S. Mauder The MEDBOX Team (2021) CC

MEDBOX Issue Brief No.17, 21 November 2021 Women's cancers have a significant impact on women's health worldwide. According to the World Health Organisation, nearly three million women are diagnosed with breast or cervical cancer every year. In this Issue Brief you will find more information.

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Managing Diabetes in Low Income Countries

Smokovski, I. Springer Nature (2021) CC2

It is now evident that we are living in a world of diabetes pandemic—despite the scientifically sound estimates, worldwide diabetes prevalence has been exceeding even the most pessimistic projections from the past. If we go back in history, it was estimated in 2004 that diabetes prevalence in 2030... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Effective Livestock Production with Low Use of Antibiotics - Online Course

Swedish University of Agricultural Sciences (SLU) (2019) C2

Learn what antibiotic resistance is and how to prevent it while increasing productivity among your livestock - This course is for livestock keepers and professionals working in the livestock production sector (such as veterinarians and advisors) in low-income countries and emerging economies worldwi... more

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COVID-19 Vaccine Acceptance

Compass (2021) CC

Social and behavior change (SBC) professionals have often been tasked to find ways to influence knowledge, attitudes, and practices, about vaccines. Now that the COVID-19 vaccines are becoming available worldwide, renewed emphasis and urgency for SBC efforts arise. To that end, WHO has offered thre... more

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Fact Sheet Hypertension

World Health Organization (WHO) World Health Organization (WHO) (2023) C_WHO

The World Health Organization's fact sheet on hypertension provides a comprehensive overview of high blood pressure, highlighting its prevalence, risk factors, and health implications. It emphasizes that hypertension is a major cause of premature death worldwide, with an estimated 1.28 billion adult... more

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Epidemiological update: Monkeypox multi-country outbreak

European Centre for Disease Prevention and Control ECDC (2022) CC

9 June 2022. This report presents an update of monkeypox confirmed cases in the European Union/European Economic Area (EU/EEA) and worldwide

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Antimicrobial stewardship in a rural regional hospital – growing a positive culture

Juanid, E.; L. Jenkins, H. Swanepoel, et al. (2018) CC

S Afr Med J 2018;108(7):546-550. DOI:10.7196/SAMJ.2018.v108i7.13149 Antimicrobial stewardship programmes have been introduced worldwide in response to the rise in antimicrobial resistance. The World Health Organization has mandated each Member State to produce a plan to address this problem. We rep... more

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Direct and indirect effects of COVID-19 on maternal and child health in Bangladesh

M. M. Ahmmed; M. A. Babu; J. Ferdosy (2021) CC

Bangladesh has been going through incremental trend of GDP growth rates for a long time. The GDP is the key aspect to measure the economic growth of a country. But the current world wide pandemic due to the COVID-19 hardly affects the world’s economy as well as Bangladesh. The present... more

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WHONET | Community website

World Health Organization WHO (2019) C_WHO

The microbiology laboratory database software. WHONET is a desktop Windows application for the management and analysis of microbiology laboratory data with a particular focus on antimicrobial resistance surveillance. WHONET, available in 28 languages, supports local, national, regional, and global ... more

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Residence Time, Water Contact, and Age-driven Schistosoma mansoni Infection in Hotspot Communities in Uganda

Moses, A.; Adriko, M.; Kibwika, B. et al. The American Jornal of Tropical Medicine and Hygiene (2021) CC

The American Jornal of Tropical Medicine and Hygiene, vol. 105, no.6, pp.1772-1781. Schistosomiasis, which is the second most important parasitic infection after malaria in terms of its socioeconomic impact, is responsible for the loss of an estimated 4.5 million disability-adjusted life years (DA... more

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Global and regional maps - overview over nutrition-related policies

Global Food Research Program et al. (2022) CC

Our global and regional maps provide a visual depiction of the locations around the world where different nutrition-related public health policies have been passed or implemented. The sugary drink tax map includes brief descriptions of over 50 taxes now passed globally, and the front-of-package labe... more

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The Need for Full Integration of Snakebite Envenoming within a Global Strategy to Combat the Neglected Tropical Diseases: The Way Forward

Gutiérrez, J.; Warrell, D.; Williams, D. et al. PLoS Neglected Tropical diseases (2013) CC

Snakebite envenoming constitutes a serious medical condition that primarily affects residents of rural communities in Africa, Asia, Latin America, and New Guinea. It is an occupational, environmental, and domestic health hazard that exacerbates the already impoverished state of these communities. Co... more

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A Second Revolution: Thirty years of child rights, and the unfinished agenda

Terre des hommes, Save the Children, Plan International, SOS Children's Villages International, World Vision, ChildFund Alliance (2019) C2

The report showed commitments made three decades ago to protect the rights of children remain unfulfilled for millions. Violence still affects countless children. Discrimination based on age, gender, disability, sexual orientation and religion harms children worldwide. Key factors include a lack ... more

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Schistosomiasis (Bilharzia) Frequently Asked Questions

The National Institute for Communicable Diseases (2018) CC

Schistosomiasis, also known as bilharzia, is a disease caused by parasitic worms that require two hosts: humans and certain species of snails. There are two forms of the disease, namely, intestinal schistosomiasis, caused by Schistosoma mansoni and S. japonicum, and urogenital schistosomiasis, cause... more

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African Trypanosomiasis

Chelsea Marie, William A. Petri, Jr. (2022) C2

Human African trypanosomiasis is caused by Trypanosoma brucei gambiense in West and Central Africa and by T. brucei rhodesiense in East Africa; both species are endemic in Uganda. Trypanosoma brucei gambiense accounts for 98% of all cases of African trypanosomiasis, and T. brucei rhodesiense account... more

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The global burden of asthma: executive summary of the GINA Dissemination Committee report

Masoli, M.; Fabian, D.; Holt, S.; Beasley, R. European Journal of allergy and clinical immunology: Volume59, Issue5 May 2004 Pages 469-478 (2004) CC2

It is estimated that as many as 300 million people of all ages, and all ethnic backgrounds, suffer from asthma and the burden of this disease to governments, health care systems, families, and patients is increasing worldwide. In 1989 the Global Initiative for Asthma (GINA) program was initiated in ... more

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World Alzheimer Report 2019

Prince, M., and J. Jackson Alzheimer's Disease International (2019) C2

Some of the key findings of the report include: Almost 80% of the general public are concerned about developing dementia at some point and 1 in 4 people think that there is nothing we can do to prevent dementia 35% of carers across the world said that they have hidden the diagnosis of de... more

Women Cancer recommended

Women Cancer
recommended