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The era of effective antibiotics is coming to a close. In just a few generations, many “miracle medicines”have been beaten into ineffectiveness by the bacteria they were intended to eradicate. Bacteria quickly adapt to the presence of antibacterial agents in order
...
to survive. The misuse of antibiotics,which is an international problem, only exacerbates the steady evolution of resistance. In August 2010, the journal Lancet Infectious Diseases posed the question "Is this the end of antibiotics?" documentingthe rapid spread of multidrug-resistant bacteriaand predicting that 10 years remain in the useful life of many agents.
more
В основе настоящих руководящих принципов лежит структура организации мероприятий в соответствии с тремя задачами:
• создание и укрепление механизмов комплексно
...
го предоставления услуг ПИН;
• уменьшение совокупного бремени ТБ, ВИЧ, вирусного гепатита и других сопутствующих патологий у ПИН посредством комплексного предоставления всеобъемлющих услуг; и
• обеспечение стандарта медико-санитарной помощи в тюрьмах, аналогичного стандарту оказания медикосанитарной помощи вне тюрем, за счет гармонизации мер вмешательства и налаживания связи со службами на уровне сообщества.
more
The document describes the use of strategic information at various stages of the response in the context of strengthening broader health information systems. Strategic information can be defined as data collected at all service delivery and administrative levels to inform policy and programme decisi
...
ons.
more
Лечение лекарственно-устойчивого туберкулеза. Что для этого нужно?
Беверли Коллин, Филипп дю Крос, Натан Форд, Джо Хатчинсон, Наташа Льюэр, Лесли Шэнкс, Франсис Варэн
Medecins Sans Frontiers
(2011)
C2
Брошюра состоит из двух частей. В первой приводятся практические примеры, иллюстрирующие все составляющие ухода за пациентами, во второй части представлены данны
...
и комментарии о последних исследованиях и разработках.
more
Модуль «Инфекционный контроль» предназначен для (медицинских) работников, которые работают в противотуберкулезных учреждениях и/или с ТБ больными. Цель этого мод
...
ля: повысить уровень их знаний по общим вопросом инфекционного контроля ТБ. Задачи: после работы с этим модулём участники смогут: – планировать мероприятия для проведения мер инфекционного контроля в конкретном учреждении
– определить степени риска трансмиссии туберкулёза
– описать меры инженерного контроля
– определить нужды для личной защиты
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Practical Guidance for collaborative interventions
Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions.
Gr
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am-negative bacteria, such as Klebsiella pneumoniae and Escherichia coli, can cause severe and often deadly infections that pose a particular threat for people with weak or not yet fully developed immune systems, including newborns, ageing populations, people undergoing surgery and cancer treatment.
The report highlights a worrying gap in activity against the highly resistant NDM-1 (New Delhi metallo-beta-lactamase 1), with only three antibiotics in the pipeline. NDM-1 makes bacteria resistant to a broad range of antibiotics, including those from the carbapenem family, which today are the last line of defence against antibiotic-resistant bacterial infections.
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Operational Guideline
Management of Diabetes Mellitus-Tuberculosis
recommended
1st edition
This resource provides practical guidance for front line health workers responsible for the diagnosis, management and care of patients with these two diseases. Published in collaboration with the World Diabetes Foundation
Securing the future from drug-resistant infections
Interagency Coordination Group on Antimicrobial Resistance IAGG
World Health Organisation WHO
(2019)
C_WHO
Antimicrobial resistance is a global crisis that threatens a century of progress in health and achievement of the Sustainable Development Goals. There is no time to wait. Unless the world acts urgently, antimicrobial resistance will have disastrous impact within a generation.
BMJ Global Health Vol.4 (2019 no.4
The Drug Resistance Index (DRI) is proposed as measure of antibiotic effectiveness in a given country, by combining, in a single metric the use of various antibiotic groups and the resistance proportions of several pathogens.It is a complicated measure that gives
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results that cannot be understood by common knowledge and logic. The DRI conveys a wrong message.
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The increasing global trend of Antimicrobial resistance (AMR) has gradually emerged as a major public health challenge for the entire world. AMR has spread to almost all countries and regions, including Pakistan owing to the “misuse and overuse” of Antimicrobials, contributing to the increasing
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burden of infections due to resistant bacteria, viruses, parasites and fungi, while limiting the treatment options for managing such infections.
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Antibiotics have been a critical public health tool since the discovery of Penicillin in 1928, saving the lives of millions of people around the world. In developing country like ours, where the burden of treatable disease is very high and access to health facilities and laboratories is difficult, a
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ntibiotics have long acted as miracle drugs. Today, however, the emergence of drug
resistance in bacteria is reversing the miracles of the past eighty years, with drug choices for the treatment of many bacterial infections becoming increasingly limited, expensive, and in some cases, nonexistent. Diseases previously regarded as relatively easy to manage are much harder to treat as doctors must use “last-resort” drugs that are more costly, take longer to work
and are often unavailable or unaffordable in developing countries. Moreover, regular prescription of antibiotics, random treatment, over the counter sales, inadequate dosage, inclusion of antibiotics in animal feeds and agriculture has contributed equally to emergence of antibiotics resistance as silent epidemic within the country.
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Confronted with the important issue of patient safety, in 2002 the Fifty-fifth World Health Assembly adopted a resolution urging countries to pay the closest possible attention to the problem and to strengthen safety and monitoring systems. In May 2004, the Fifty-seventh World Health Assembly approv
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ed the creation of an international alliance as a global initiative to improve patient safety. The World Alliance for Patient Safety was launched in October 2004 and currently has its place in the WHO Patient Safety programme included in the Information, Evidence and Research Cluster.
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