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Breakthrough ACTION a développé des affiches, des spots audiovisuels et des bannières pour le lancement du vaccin antipaludique R21/Matrix M en la République du Congo. Ces messages visent à promouvoir l’acceptation et l’utilisation du vaccin contre le paludisme. Cet effort a impliqué une c
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ollaboration avec des experts techniques de divers partenaires et des membres de la Task-Force Communication Paludisme, le Programme National de Lutte contre le Paludisme, ainsi qu’avec le Programme Elargi de Vaccination.
Accessed on 15/07/2025.
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The ACT Consortium was an international research collaboration dedicated to evaluating the effectiveness, safety and implementation of artemisinin-based combination therapies (ACTs) for treating malaria. Operating across multiple countries in Africa and Asia, the consortium conducted over 25 studies
...
focused on improving malaria case management, drug delivery, diagnostic practices and patient outcomes. Emphasising interdisciplinary research, the consortium generated robust evidence to inform national malaria control policies and global health strategies. This website serves as a comprehensive archive of the consortium's work, providing researchers, policymakers, and programme implementers in global health and infectious disease control with access to protocols, guidance documents, data tools, and peer-reviewed publications.
Accessed on 15/0//2025.
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RBM Partnership to End Malaria
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The RBM Partnership to End Malaria is a global coalition comprising over 500 partners, including governments, international organisations, the private sector and civil society, who are all dedicated to ending malaria worldwide. Through coordinated advocacy, resource mobilisation and technical suppor
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t, the Partnership strengthens national malaria control programmes and accelerates progress towards malaria elimination.
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This guide provides strategic direction for host countries, event organizers, health authorities, and key stakeholders to effectively plan and conduct Simulation Exercises (SimEx) and After Action Reviews (AARs) for mass gathering events. Packed with practical tools, it empowers users to seamlessly
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integrate these activities into ongoing learning and emergency risk management processes. Aligned with the International Health Regulations (IHR, 2005), the guide serves as a critical resource for strengthening global and national health resilience, ensuring safer and more prepared mass gatherings.
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This document on logistics management information systems (LMIS) was developed to address the increasing need for harmonization and standardization of core indicators for managing medicines and health products for neglected tropical diseases (NTDs) at country level (i.e. for last-mile logistics). It
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thereby responds to requests from Members States, pharmaceutical groups, financial donors and implementing partners for guidance from the World Health Organization (WHO) for a transparent, standardized reporting mechanism and key indicators for in-country logistics. More importantly, this document will also guide the last-mile logistics process and is relevant for the health workforce working at different levels of national health information systems. It can be adapted and used for any health products depending on the needs of the country or health programmes.
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Pregnant travelers face numerous risks, notably increased susceptibility to or severity of multiple infections, including malaria. Because pregnant women residing in areas non-endemic for malaria are unlikely to have protective immunity, travel to endemic areas poses risk of severe illness and pregn
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ancy complications, such as low birthweight and fetal loss. If travel to malaria-endemic areas cannot be avoided, preventive measures are critical. However, malaria chemoprophylaxis in pregnancy can be challenging, since commonly used regimens have varying levels of safety data and national guidelines differ. Furthermore, although chloroquine and mefloquine have wide acceptance for use in pregnancy, regional malaria resistance and non-pregnancy contraindications limit their use. Mosquito repellents, including N,N-diethyl-m-toluamide (DEET) and permethrin treatment of clothing, are considered safe in pregnancy and important to prevent malaria as well as other arthropod-borne infections such as Zika virus infection. Pregnant travelers at risk for malaria exposure should be advised to seek medical attention immediately if any symptoms of illness, particularly fever, develop.
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To mark the International Day of the African Child, Medicines for Malaria Venture (MMV) celebrated the inclusion of three of its antimalarial medicines on the WHO Model List of Essential Medicines (EML) and the EML for Children (EMLc). These are two artemisinin-based combination therapies (ACTs) for
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adults, children and infants, and a rectal artesunate formulation for the pre-referral treatment of severe malaria in young children. The approved therapies — pyronaridine–artesunate, dihydroartemisinin–piperaquine and rectal artesunate — offer child-friendly formulations and are the first-line treatment for uncomplicated malaria caused by Plasmodium falciparum and P. vivax. Inclusion in the EMLc facilitates national adoption, improves access to high-quality treatments and addresses the disproportionate malaria burden among children under five. This supports global efforts to reduce malaria mortality and advance elimination.
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Antimicrobial resistance (AMR) and malaria remain significant public health challenges in the WHO Eastern Mediterranean Region (EMR). In 2021, the region reported 1.7 million sepsis-related deaths, with 373,000 associated with bacterial AMR. High antibiotic consumption, particularly in high-income c
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ountries, combined with rising usage in middle-income countries, has accelerated the emergence of drug-resistant infections. Malaria management is further complicated by biological threats, including vector insecticide resistance, PFHRP2/3 gene deletions, and antimalarial drug resistance, alongside insufficient trained personnel and limited molecular surveillance capacity. Effective strategies to address these challenges include strengthening regional and cross-border surveillance networks, designating WHO collaborating centers for molecular monitoring, enforcing national treatment policies, and raising public and healthcare provider awareness about rational antimalarial and antibiotic use. These measures, coupled with sustainable funding and enhanced therapeutic efficacy studies, are essential to reduce the development and spread of drug-resistant malaria and improve overall health outcomes in the EMR.
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Promoting and protecting the mental health and psychosocial wellbeing of children, adolescents, and their caregivers remains undamental to achieving the Sustainable Development Goals (SDGs), with a direct contribution to SDG 3 (Good Health and Well- eing). In 2024, UNICEF accelerated the scale-up o
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f integrated, multisectoral MHPSS programming. These efforts contributed to the strengthening of national and subnational child and adolescent mental health systems by supporting programming across the continuum of care, investing in workforce development, advancing data systems and evidence generation, and promoting institutional leadership and coordination mechanisms. UNICEF’s growing reach, particularly through health, education, and child protection systems, reflects a strategic commitment to embedding MHPSS in sustainable development frameworks and in responses that bridge humanitarian action and development programming.
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The WHO’s Early Warning, Alert and Response System (EWARS) is a tool used in emergencies such as conflicts or natural disasters to quickly detect and respond to disease outbreaks. It helps set up simple and reliable surveillance systems even in places without stable electricity or internet, using
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kits that include phones, laptops, and solar chargers. EWARS supports national health authorities during crises and can later be integrated into the regular health surveillance system.
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The WHO handbook “Epidemiological Data Analysis for the Early Warning Alert and Response Network (EWARN) in Humanitarian Emergencies” explains how to collect, analyse, interpret, and share health data during crises such as conflicts or natural disasters. It is a practical guide for health and su
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rveillance officers to detect disease outbreaks early and guide quick public health responses. The document outlines steps for managing data at different levels (local, regional, national), analysing disease trends by time, place, and person, and using indicators to monitor outbreak risks. It also provides methods for interpreting and communicating results clearly to decision-makers to support effective health interventions in emergencies.
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Epidemics and pandemics are some of the biggest threats to a safe and healthy world. But with effective preparedness and response measures, we can reduce their impacts and even stop them in their tracks.
Through the Programmatic Partnership with the European Union, 24 local Red Cross and Red Cres
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cent Societies have been working to keep communities healthy and safe from epidemics and pandemics with technical assistance, advocacy support and coordination from IFRC and European National Societies. They do so by equipping communities with knowledge and tools to stop the spread of diseases and by setting up systems so they can report outbreaks quickly, enabling a rapid response from authorities. National Societies have also significantly developed their own epidemic preparedness and response capacity.
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Global tuberculosis report 2025
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The WHO Global tuberculosis report 2025 provides a comprehensive and up-to-date assessment of the TB epidemic and of progress in prevention, diagnosis and treatment of the disease, at global, regional and country levels. This is done in the context of global TB commitments, strategies and targets.
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The 2025 edition of the report is, as usual, based primarily on data gathered by WHO from national ministries of health in annual rounds of data collection. In 2025, 184 countries and areas with more than 99% of the world’s population and TB cases reported data.
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Building true health security in a global age. Findings and recommendations of the Global Council. In landmark findings based on two years of research and convenings around the world, the new report shows that high levels of inequality are linked to outbreaks becoming pandemics and that inequality i
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s undermining national and global responses, making pandemics more disruptive, deadly, and longer in duration. The report also shows that pandemics increase inequality, fuelling a cycle that research shows is visible not just for COVID-19, but also for AIDS, Ebola, Influenza, Mpox and beyond.
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Progress report and road map. Countries included in this report: Algeria, Afghanistan, Bahrain, Djibouti, Egypt, the Islamic Republic of Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Morocco, Oman, Pakistan, Qatar, State of Palestine, Saudi Arabia, Somalia, Sudan, the Syrian Arab Republic, Tunisia, Un
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ited Arab Emirates, Yemen.
To support countries in the region to achieve triple elimination goals, this report collects and assesses national policies and key indicators on EMTCT efforts against WHO criteria for validation of the EMTCT of HIV, syphilis and HBV. Based on analysis and consultations with national policymakers, the report provides a Road Map for countries at different stages of readiness to follow towards triple elimination goals.
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Renforcement de la surveillance et du partage d’informations à l’échelle transfrontalière en Afrique
Le document intitulé « Strategic Framework for Strengthening Cross-Border Surveillance and Information Sharing in Africa » présente une stratégie coordonnée élaborée par Africa CDC afin d’améliorer la surveillance de la santé publique et la collaboration au-delà des frontières national
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es en Afrique. Il met en évidence le défi posé par le fait que les maladies infectieuses se propagent fréquemment au-delà des frontières en raison des mouvements de population, du commerce et des migrations, tandis que les systèmes de surveillance et les mécanismes de partage des données restent souvent centrés sur le niveau national et fragmentés.
Le cadre stratégique propose de renforcer la coordination régionale, d’harmoniser les systèmes de surveillance, d’améliorer le partage d’informations entre les pays et de développer les capacités des laboratoires ainsi que des ressources humaines. Il souligne également l’importance de la détection rapide des menaces sanitaires transfrontalières, des enquêtes conjointes sur les flambées épidémiques et d’une meilleure communication entre les États membres. Dans l’ensemble, le document vise à renforcer la préparation, les systèmes d’alerte précoce et la réponse collective aux menaces de santé publique sur le continent africain.
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The webpage ”H5 Reference Laboratories” on the WHO Global Influenza Surveillance and Response System (GISRS) site describes a network of specialized laboratories designated by the World Health Organization to support global influenza monitoring — particularly for H5 subtype avian influenza vir
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uses.
It explains that these reference laboratories perform high-level testing, characterization, and sharing of influenza virus samples, including genetic sequencing and antigenic analysis. Their role is to help detect and assess influenza virus strains of public health concern (especially H5 strains with pandemic potential), support vaccine strain selection, and provide technical guidance and capacity building to national influenza centers and other laboratories. The page highlights the importance of this global laboratory network in strengthening early warning, risk assessment, and preparedness for influenza outbreaks and pandemics.
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The webpage explains “Preparedness 2.0,” a regional strategy by the World Health Organization (WHO) for Europe aimed at strengthening countries’ ability to prevent, prepare for, and respond to health emergencies. It outlines a five-year action plan (2024–2029) that supports member states in
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building resilient health systems, improving coordination, and enhancing capacities for dealing with future crises such as pandemics or other public health threats. The approach emphasizes continuous learning, cooperation across sectors, and aligning national plans with global health security frameworks, while providing practical tools and guidance to help countries implement and improve their preparedness strategies.
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The webpage describes how the Preparedness and Resilience for Emerging Threats (PRET) initiative is being implemented in the Americas to strengthen pandemic preparedness and response. It explains that PRET promotes a unified approach by grouping diseases according to how they spread (such as respira
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tory or vector-borne), allowing countries to use shared systems and resources more efficiently. The initiative focuses on improving coordination, reducing duplication of efforts, and aligning technical strategies across countries. PAHO supports countries in developing and updating national preparedness plans—especially for respiratory pandemics—through structured steps and by providing access to existing national plans and resources. Overall, the text highlights regional collaboration and capacity-building to ensure that countries in the Americas are better prepared for future health emergencies.
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This guide aims to support the implementation of evidence-based practices to reduce morbidity and mortality due to postpartum haemorrhage (PPH). Implementation is a multidisciplinary process that requires engagement from multiple stakeholders. Furthermore, implementation can and should be pursued in
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a systematic and evidence-based manner.
This Implementation guide presents a structured process that will aid countries in their efforts to incorporate the latest PPH recommendations into national PPH guidelines and clinical practice.
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