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Relapsing malaria caused by Plasmodium vivax parasites poses a significant challenge to global malaria elimination efforts. About one third of the population remains at risk of contracting P. vivax malaria, and 85% of P. vivax infections stem from reactivated latent parasites, leading to chronic ana
...
emia and increased morbidity and mortality. In addition to diagnostic tools that can detect the acute, blood-stage of P. vivax, new tools are needed to detect the dormant infections before they reactivate and contribute to morbidity and onwards transmission
more
This Implementation Kit (I-Kit) is designed to support SBCC and Malaria in Pregnancy (MiP) programme managers in improving their communication strategies, particularly those targeting healthcare workers. It provides practical guidance on four key planning areas and emphasises the significant health
...
risks that malaria poses to mothers and newborns. The I-Kit highlights evidence-based WHO interventions and addresses barriers to access, demand and the delivery of MiP services by providers. Despite progress in reducing malaria, uptake of preventive measures remains low, highlighting the need for targeted advocacy and improved SBCC strategies.
more
PLOS Glob Public Health 3(7): e0001132. https://doi.org/10.1371/journal.
pgph.0001132
This paper proposes a framework for strategic communications for malaria governance that involves five key elements: knowing the audience, defining the message, designing a medium, identifying a messenger, and
...
selecting the timing
more
International Journal of Advances in Medicine. Vol. 7 No. 7 (2020): July 2020 . This study explores the clinical characteristics and outcomes of patients with concurrent malaria and HIV infection, a combination that is relatively understudied in India.
Malaria in children presents significant clinical challenges, with variations in presentation based on the malaria parasite involved and the child's underlying health conditions. The World Health Organization reports high incidence rates, particularly in sub-Saharan Africa, and emphasizes the import
...
ance of effective treatment strategies. First-line treatment often involves Artemether-Lumefantrine (ALu), while severe malaria requires careful management and the use of intravenous Quinine. Management protocols emphasize early diagnosis and the monitoring of severe complications to reduce mortality.
more
Community led-monitoring is based on the principle that «Nothing that is done for us should
be done without us”. The combination of this principle with evidence shows that community-led
monitoring is an important driver of improved service delivery and health outcomes that needs to
be re-empha
...
sized. Thus, the community must participate at all stages of the fight against malaria.
This guide will be useful to CSOs working in the field of malaria in the conduct of community-led
monitoring of activities efficiently and allow these CSOs to know their role and responsibilities in this
exercise at each key stage. This guide will also provide CSOs and communities affected by malaria
with templates of monitoring tools adapted to key malaria programs.
more
This course will provide basic knowledge about the burden of malaria and effective tools to both treat and prevent malaria, and discuss the challenges and opportunities for taking these interventions to scale.
Le paludisme reste un enjeu majeur de santé publique dans de nombreux pays à faible et moyen revenu. En 2018, l’OMS estimait à environ 228 millions le nombre de cas de paludisme, responsable de 405 000 décès principalement en Afrique subsaharienne. L’utilisation intensive des outils antipal
...
udiques disponibles a permis de réduire significativement la transmission dans de nombreuses régions endémiques au cours de la dernière décennie. Cependant, l’éradication du paludisme dans les zones à forte transmission reste une perspective lointaine.
Ce MOOC offre aux participants un aperçu complet des diverses disciplines et questions clés de la recherche sur le paludisme. Il aborde notamment la biologie cellulaire et moléculaire des parasites, la recherche clinique sur le terrain et en milieu hospitalier, les technologies génomiques avancées, la recherche translationnelle sur les nouveaux outils de lutte contre les parasites et vecteurs (médicaments, vaccins), l’épidémiologie du paludisme et la recherche clinique en santé publique. Le cours est accessible à toute personne intéressée par le paludisme, à condition de posséder une formation initiale en sciences de la vie.
Ce MOOC fait partie des MOOCs du Diplôme des Maladies Infectieuses de l’Institut Pasteur (DNM2IP).
more
Malaria remains a significant public health challenge in the South-East Asia Region, which bears the second highest malaria burden in the world.
Target Malaria is an innovative project that aims to reduce the population of mosquitoes that transmit malaria in sub-Saharan Africa, thereby decreasing disease transmission. As part of its work to combat malaria, Target Malaria has started contained studies at the Uganda Virus Research Institute (U
...
VRI) in Uganda.
Accessed on 01/07/2025.
more
National malaria social and behavior change (SBC) and social and behavior change communication (SBCC) strategies are effective for describing the priorities and focus of a country’s malaria behavior change efforts. The strategy indicates how partners will work to influence specific behaviors and i
...
mprove malaria outcomes.
more
This WHO video presents updated recommendations on two new types of insecticide-treated nets (ITNs) designed to combat mosquito resistance: nets containing either pyrethroid and chlorfenapyr or pyrethroid and pyriproxyfen. The video highlights the improved effectiveness of these nets compared to sta
...
ndard nets and emphasises the importance of their universal use in malaria-endemic areas, particularly for pregnant women and young children where supplies are limited.
more
This document outlines the best practices for mosquito control and surveillance in United Nations duty stations affected by mosquito-borne diseases. It sets out an integrated vector management (IVM) approach combining environmental, biological, mechanical, chemical and personal protection strategies
...
to reduce mosquito populations and the transmission of diseases. Key elements include targeted control of larval and adult mosquitoes, the proper use of insecticides, community engagement, and ongoing surveillance.
more
This WHO guidance outlines reactive strategies to interrupt malaria transmission in areas nearing elimination or to prevent re-establishment, triggered by confirmed cases.
Vector control, alongside case management, remains the most effective approach to controlling and eliminating malaria. Key interventions, such as indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs), have significantly reduced malaria transmission in many African countries. This
...
has enabled some countries to transition from the control phase to the elimination phase.
more
La gravité de la récente situation épidémiologique en Amérique latine, marquee par la co-circulation des virus de la dengue, du chikungunya et du Zika, l’émergence d’épizootie de fièvre jaune et l’apparition de cas de microcéphalie et d’autres maladies associées (p. ex. le syndrome
...
de Guillain-Barré) et l’émergence d’épizooties de fièvre jaune ont amené l’Organisation mondiale de la Santé à déclarer une situation d’urgence dans les Amériques en 2016.1 En l’absence d’un traitement spécifique et de vaccins contre la dengue, le chikungunya et le virus Zika, et compte tenu des limitations des stratégies de lutte antivectorielle, l’OMS a préconisé une meilleure utilisation des alternatives disponibles pour améliorer la lutte contre le moustique vecteur Aedes aegypti, ainsi que des activités complémentaires.
more
The TACT training manuals and patient leaflet were developed as part of the ACT Consortium's initiative to improve malaria case management by promoting the correct use of rapid diagnostic tests (RDTs). The TACT ("Targeting ACTs") initiative aims to ensure that artemisinin-based combination therapies
...
(ACTs) are used appropriately, treating only confirmed malaria cases and guiding alternative care for other febrile illnesses.
Please download the manuals and leaflets from the website
more
Les manuels de formation TACT et la brochure destinée aux patients ont été élaborés dans le cadre de l'initiative du consortium ACT visant à améliorer la prise en charge du paludisme en encourageant l'utilisation correcte des tests de diagnostic rapide (TDR). L'initiative TACT (Targeting ACTs
...
) vise à garantir l'utilisation appropriée des combinaisons thérapeutiques à base d'artémisinine (ACT), en ne traitant que les cas de paludisme confirmés et en orientant les patients vers d'autres traitements pour les maladies fébriles non liées au paludisme. Les manuels proposent une formation interactive sur le lieu de travail pour aider les personnels de santé à passer d'un traitement présomptif à un diagnostic fondé sur des tests, conformément à la politique de l'OMS. La brochure d'accompagnement destinée aux patients, disponible en anglais et en swahili, s'appuie sur des récits illustrés pour expliquer l'utilité et le fonctionnement des TDR, répondre aux inquiétudes les plus courantes et encourager la confiance dans les résultats des tests. Ces documents, dont la clarté et la compréhension ont été testées au préalable, permettent d'opérer des changements durables dans la pratique clinique et la communication avec les patients au sein des établissements de soins primaires tanzaniens.
Accessed on 03/07/2025.
more
Os manuais de formação TACT e o folheto para o paciente foram desenvolvidos no âmbito da iniciativa do ACT Consortium para melhorar a gestão dos casos de malária e promover a utilização correta dos testes de diagnóstico rápido (RDT). A iniciativa TACT ("Targeting ACTs") visa garantir a util
...
ização adequada das terapias combinadas à base de artemisinina (ACT), tratando apenas os casos de malária confirmados e orientando os cuidados alternativos para outras doenças febris. Os manuais oferecem formação interativa, baseada no local de trabalho, para auxiliar os profissionais de saúde na transição do tratamento presuntivo para um diagnóstico baseado em testes, em conformidade com a política da OMS. O folheto para o paciente, disponível em inglês e suáili, utiliza histórias ilustradas para explicar a importância e o objetivo dos TDR, abordar preocupações comuns e incentivar a confiança nos resultados dos testes. Após terem sido pré-testados quanto à sua clareza e compreensão, estes materiais apoiam mudanças sustentáveis na prática clínica e na comunicação com os doentes no âmbito dos cuidados de saúde primários na Tanzânia.
Accessed on 03/07/2025.
more
The Bill & Melinda Gates Foundation is committed to eradicating malaria, a disease that continues to cause hundreds of thousands of deaths every year, primarily in sub-Saharan Africa.
