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Diagnostic Gaps and Recommendations for Human African Trypanosomiasis: Assessment of User Needs, Use Cases, and the Diagnostic Landscape

Program for Appropriate Technology in Health PATH (2016) C2
This analysis focused on the chronic form of HAT caused by T. b. gambiense, as it contributes to the majority of disease burden. Information from the literature review, product development landscape, and stakeholder interviews was compiled to: - Identify use cases and understand current diagnosti... more
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Emergency health response plan for drought in Somalia: Early action to protect health and save lives April-December 2022

World Health Organisation (WHO) (2022) C_WHO
Nearly 260 000 people died in parts of Somalia between October 2010 and April 2012, including 133 000 children under five during the famine and food crisis in Somalia making it the worst famine in history. A study commissioned and funded by the Food and Agriculture Organization of the United Natio... more
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Preventing and responding to sexual misconduct WHO’s three-year strategy 2023-2025

World Health Organisation (WHO) (2023) C_WHO
Sexual exploitation, sexual abuse and sexual harassment (SEAH) violate the rights and wellbeing of the people we serve and the people with whom we serve. Such behaviours are directly in opposition to WHO’s values and our abiding responsibility to do no harm. WHO uses the umbrella term “sexual mi... more
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Mali national action plan on antimicrobial resistance: review of progress in the human health sector

World Health Organisation (WHO) (2023) C_WHO
This policy brief aims to provide a review of the current progress on implementing the Mali national action plan on AMR, identifies critical gaps, and highlights findings to accelerate further progress in the human health sector. The target audience includes all those concerned with implementing act... more
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Learning Modules. COVID-19 Vaccines in Pregnancy and Safe Breastfeeding

Pan American Health Organization (PAHO) (2023) C_WHO
This is an e-learning module with the objective of providing education for health professionals and pregnant women using published results and studies based on COVID-19 surveillance data, which have indicated an increased risk among pregnant women of presenting with severe forms of COVID-19 and, the... more
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Elimination of onchocerciasis in Africa by 2025: the need for a broad perspective

Cupp, E.; Sauerbrey, M.; Cama, V. et al. National Library of Medicine (2019) CC
In response to the recent publication “Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes” by Dadzie et al., it is important to clarify and highlight the positive and unequivocal research and operational contributio... more
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Role of APOC in the new strategic direction for Onchocerciasis elimination, co-implementation with Lymphatic filariasis and other health interventions

World Health Organization WHO; African Programme for Onchocerciasis Control APOC (2012) C_WHO
The Onchocerciasis Control Programme in West Africa (OCP) undertook regional and large scale frght against onchocerciasis in West Africa in 1974 using a vector control strategy. By 2002 OCP had succeeded in eliminating the disease as a public health, socio-economic and development problem in 10 out ... more
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Health professionals’ knowledge about prevention and control of leishmaniosis

Alves, G., de Oliveira T., Nodari N. et al. Journal of Community Medicine (2019) CC
Leishmaniasis is an important worldwide disease with a zoonotic potential that presenting visceral and cutaneous clinical forms. The domestic dog is seen as the main reservoir of Leishmania spp. and for this reason, it is the target of the control program in some countries. The health professiona... more
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“Female genital schistosomiasis is a sexually transmitted disease”: Gaps in healthcare workers’ knowledge about female genital schistosomiasis in Tanzania

Mazigo, H.; Samson, A.; Lambert, V. et al. PLoS Global Public Health (2022) CC
Female Genital Schistosomiasis (FGS) is a gynaecological disease caused by Schistosoma haematobium, a parasitic worm that is acquired by skin contact with freshwater contaminated by schistosome cerceriae. Communities in which the infection is most endemic have limited access to clean water and healt... more
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Monitoring the elimination of human African trypanosomiasis at continental and country level: Update to 2018

Franco, JR.; Cecchi, G.; Priotto, G.; Paone, M.; Diarra, A. et al. (2020) CC
Over the past twenty years, huge efforts made by a broad coalition of stakeholders curbed the last epidemic and brought the disease to the brink of elimination. In this paper, the latest figures on disease occurrence, geographical distribution and control activities are presented. Strong evidence in... more
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Diagnosis and Clinical Management of Chagas Disease: An Increasing Challenge in Non-Endemic Areas

Suárez, C., Nolder, D., García-Mingo, A. et al. Research and reports in tropical medicine (2022) CC
Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in Central, South America, Mexico and the South of the United States. It is an important cause of early mortality and morbidity, and it is associated with poverty and stigma. A third of the cases evolve into chronic... more
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Clinical Presentation of T.b. rhodesiense Sleeping Sickness in Second Stage Patients from Tanzania and Uganda

Kuepfer, I.; Hhary, EP.; Mpairwe, A.; Edielu, A.; Burri, C.; Blum, JA. PLOS Neglected Tropical Diseases (2011) CC
A wide spectrum of disease severity has been described for Human African Trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense (T.b. rhodesiense), ranging from chronic disease patterns in southern countries of East Africa to an increase in virulence towards the north. However, only limited d... more
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Knowledge, attitudes and practices about human African trypanosomiasis and their implications in designing intervention strategies for Yei county, South Sudan

Bukachi, SA.; Mumbo, AA.; Alak, ACD.; Sebit, W.; Rumunu, J. et al. PLOS Neclected Tropical Diseases (2018) CC
A clear understanding of the knowledge, attitudes and practices (KAP) of a particular community is necessary in order to improve control of human African trypanosomiasis (HAT).New screening and diagnostic tools and strategies were introduced into South Sudan, as part of integrated delivery of primar... more
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Tsetse Control and Gambian Sleeping Sickness; Implications for Control Strategy

Tirados, I.; Esterhuizen, J.; Kovacic, V.; Mangwiro, TNC.; Vale, GA et al. PLOS Neglected Tropical Diseases (2015) CC
Sleeping sickness is controlled by case detection and treatment but this often only reaches less than 75% of the population. Vector control is capable of completely interrupting HAT transmission but is not used because of expense. We conducted a full scale field trial of a refined vector control tec... more
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Emergeny Appeal Syria, MENA | Syria Earthquake

International Federation of Red Cross and Red Crescent Societies (IFRC) (2023) CC
On 6 February at 4:17 am, a 7.8 degrees magnitude earthquake struck southern Turkey near Syria’s northern border. The US Geological Survey said the earthquake was centered about 33 km (20 miles) from Gaziantep, a major city and provincial capital. Tremors were felt as far away as Lebanon, Greece... more
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WHO guidelines on parenting interventions to prevent maltreatment and enhance parent–child relationships with children aged 0–17 years

World Health Organisation (WHO) (2023) C_WHO
This guideline provides evidence-based recommendations on parenting interventions for parents and caregivers of children aged 0–17 years that are designed to reduce child maltreatment and harsh parenting, enhance the parent–child relationship, and prevent poor mental health among parents and emo... more
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Gambiense human African trypanosomiasis: the bumpy road to elimination

Hasker E, Hope A, Bottieau E. Wolters Kluwer Health, Inc. (2022) C2
Gambiense human African trypanosomiasis is a deadly infectious disease affecting West and Central Africa, South Sudan and Uganda, and transmitted between humans by tsetse flies. The disease has caused several major epidemics, the latest one in the 1990s. Thanks to recent innovations such as rapid di... more
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Target product profile for a point-of-care diagnostic test for dermal leishmaniases - Control of Neglected Tropical Diseases

World Health Organization WHO (2022) C_WHO
Localized cutaneous leishmaniasis and its evolving forms (diffuse cutaneous leishmaniasis, mucosal leishmaniasis and cutaneous leishmaniasis recidivans), together with the sequela of visceral leishmaniasis (post-kala-azar dermal leishmaniasis), account for about one million cases of dermal leishmani... more
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WHO Eritrea 2022 Annual Report

World Health Organisation (WHO) (2023) C_WHO
During the year 2022, COVID-19 continued to be a significant challenge in Eritrea as in many other countries across the world. As COVID-19 devastated communities around the world, WHO worked with the MoH to strengthen the National and Sub-National health systems in order to meet community needs and ... more
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Responding to child maltreatment: a clinical handbook for health professionals

World Health Organisation (WHO) (2022) C_WHO
This handbook is intended primarily for front-line health care providers who are likely to see children (among other clients) in their day-to-day practice. These may include general practitioners, nurses, midwives, gynaecologists, paediatricians, mental health professionals, first responders and st... more